Research field (7)：
Mathematical informatics
, Human pathology
, Bio-, chemical, and soft-matter physics
, Biophysics
, Molecular biology
, Neuroanatomy and physiology
, Neuroscience - general
Research theme for competitive and other funds (1)：
2020 - 2023 全脳ニューロンアトラスによる神経変性疾患モデルの一細胞解像度全脳病態解析
Papers (8)：
Tomoki T Mitani, Etsuo A Susaki, Katsuhiko Matsumoto, Hiroki R Ueda. Realization of cellomics to dive into the whole-body or whole-organ cell cloud. Nature methods. 2024
Tomoki T Mitani, Katsuhiko Matsumoto, Hiroki R Ueda. WHOLE-BRAIN CELLOME-WIDE ASSOCIATION STUDY (CWAS) UNVEILS NEURODEGENERATIVE TRAJECTORIES IN A 3D CELLULAR LANDSCAPE. IBRO Neuroscience Reports. 2023. 15. 1. S451-S451
Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, et al. Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep. PLOS Biology. 2022. 20. 10. e3001813-e3001813
Satoshi Nojima, Shoichi Ishida, Kei Terayama, Katsuhiko Matsumoto, Takahiro Matsui, Shinichiro Tahara, Kenji Ohshima, Hiroki Kiyokawa, Kansuke Kido, Koto Ukon, et al. A novel three-dimensional imaging system based on polysaccharide staining for accurate histopathological diagnosis of inflammatory bowel diseases. Cellular and molecular gastroenterology and hepatology. 2022. 14. 4. 905-924
Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, et al. Realization of phosphorylation hypothesis of sleep by mammalian CaMKIIβ. 2021
MICROSCOPE, VIEWING METHOD, CONTROL PROGRAM AND DEVICE
Books (3)：
Next-generation whole-organ all-cell imaging driven by MOVIE microscopy
2023
3D pathology by tissue-clearing technique
Precision Medicine 2023
Whole-organ cells profiling using tissue-clearing method "CUBIC"
Precision Medicine 2019
Lectures and oral presentations (18)：
Whole-Brain Cellome-Wide Association Study (CWAS) reveals Microscale Neurodegenerative Trajectories in a 3D Cellular Landscape
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
Whole-Brain Cellome-Wide Association Study (CWAS) reveals Microscale Neurodegenerative Trajectories in a 3D Cellular Landscape
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
Cellome-Wide Association Studies (CWAS) for Comprehensive 3D Analysis of Spatial Lesions and Microenvironments
(An invitation-only seminar hosted by Beth Israel Deaconess Medical Center/Harvard Medical School 2023)
Whole-brain Cellome-Wide Association Study (CWAS) reveals neurodegenerative trajectories in a 3D cellular landscape
(Neuroscience 2023 2023)
Towards Single-Cell Precision Medicine: Ultra-Early Detection in Neurodegeneration with 3D Subcellular Light-Sheet Imaging
(An invitation-only seminar hosted by the Interdisciplinary Brain Center (IBC) and the Alzheimer's Clinical & Translational Research Unit (ACTRU) at Massachusetts General Hospital, affiliated with Harvard Medical School, located in Boston, MA. 2023)
