Research theme for competitive and other funds (15):
2022 - 2025 Protection by suppression of microglial inflammation in rat glaucoma models
2018 - 2021 The neurosteroid allopregnanolone and its enantiomer protects retinal neurons by effects on autophagy and GABAA receptors in rat glaucoma models
2015 - 2018 Neurosteroids modulate the effects of high pressure in a rat ex vivo glaucoma model
2016 - 2017 前房水中の神経ステロイドは緑内障進行のバイオマーカーとなり得るか
2014 - 2017 正常眼圧緑内障-進行因子の解明および自然経過-
2013 - 2016 Development of new glaucoma therapy other than decreasing intraocular pressure
2012 - 2015 Neuroprotection by enhancement of glutamate uptake against pressure-induced injury in a rat glaucoma model
2012 - 2013 緑内障性視神経障害に対するニューロステロイド型神経保護治療薬の開発
2011 - 2012 Development of experiment device to investigate neuroprotection using new glaucoma model
1996 - 1997 VKH disease・原田病特異的抗原の検索-SDS不溶性成分の検索
1994 - 1994 原田病の分子免疫学的研究
1991 - 1992 Ultrastructure of postsynaptic active zones associated with different type of receptors.
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Papers (124):
Michiko Ohno-Oishi, Zou Meiai, Kota Sato, Seiya Kanno, Chihiro Kawano, Makoto Ishikawa, Toru Nakazawa. SH-SY5Y human neuronal cells with mutations of the CDKN2B-AS1 gene are vulnerable under cultured conditions. Biochemistry and Biophysics Reports. 2024. 38
Kota Sato, Michiko Ohno-Oishi, Masaaki Yoshida, Taimu Sato, Takaharu Aizawa, Yuto Sasaki, Shigeto Maekawa, Makoto Ishikawa, Kazuko Omodaka, Chihiro Kawano, et al. The GPR84 molecule is a mediator of a subpopulation of retinal microglia that promote TNF/IL-1α expression via the rho-ROCK pathway after optic nerve injury. GLIA. 2023. 71. 11. 2609-2622
Rei Sakata, Makoto Araie, Takeshi Yoshitomi, Takeshi Yoshitomi, Makoto Ishikawa, Haruki Abe, Takeo Fukuchi, Kazuhisa Sugiyama, Shinji Ohkubo, Koji Nitta, et al. Factors associated with visual field or structure progression occurring first in a prospective study on patients with untreated open-angle glaucoma with normal intraocular pressure. Eye. 2023. 38. 4. 737-744
ALLOPREGNANOLONE PREVENTS PRESSURE-INDUCED RETINAL INJURY VIA ACTIVATION OF AUTOPHAGY IN A RET IN VIVO GLAUCOMA MODEL
(9th World glaucoma E-Congress Abstarct book 2021)