Rchr
J-GLOBAL ID:201901000835359609   Update date: Feb. 05, 2024

Arakawa Ryosuke

アラカワ リョウスケ | Arakawa Ryosuke
Affiliation and department:
Job title: Graduate School Professor
Research field  (2): Pharmacology ,  Psychiatry
Research keywords  (2): 薬理学 ,  精神医学
Research theme for competitive and other funds  (4):
  • 2020 - 2023 タウ蛋白PETイメージングからみた老年期うつ病の治療反応性の解明
  • 2019 - 2022 The role of tau protein and 5-HT1B receptor in the amyloid associated depression by positron emission tomography
  • 2009 - 2011 Effects of antipsychotic drugs on pre-and postsynaptic dopaminergic functions measured by PET
  • 2008 - 抗精神病薬による下垂体ドーパミンD2受容体占有率の脳内局所差に関する研究
Papers (145):
  • Sangram Nag, Kevin Jia, Ryosuke Arakawa, Prodip Datta, Daniel Scott, Christopher Shaffer, Mohammad Mahdi Moein, Matthew Hutchison, Maciej Kaliszczak, Christer Halldin. Synthesis of [11C]BIIB104, an α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic-Acid-Positive Allosteric Modulator, and Evaluation of the Bio-Distribution in Non-Human Primate Brains Using Positron Emission Tomography. Molecules (Basel, Switzerland). 2024. 29. 2
  • Magnus Schou, Nahid Amini, Akihiro Takano, Ryosuke Arakawa, Kenneth Dahl, Miklos Toth, Marie Svedberg, Andrea Varrone, Christer Halldin. Microsome Mediated in Vitro Metabolism: A Convenient Method for the Preparation of the PET Radioligand Metabolite [18F]FE-PE2I-OH for Translational Dopamine Transporter Imaging. ACS chemical neuroscience. 2023. 14. 20. 3732-3736
  • Brendon E Cook, Sangram Nag, Ryosuke Arakawa, Edward Yin-Shiang Lin, Nancy Stratman, Kevin Guckian, Heike Hering, Mukesh Lulla, Jinkuk Choi, Cristian Salinas, et al. Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023
  • Sangram Nag, Martin Bolin, Prodip Datta, Ryosuke Arakawa, Anton Forsberg Morén, Yasir Khani Maynaq, Edward Lin, Nathan Genung, Heike Hering, Kevin Guckian, et al. Development of a Novel [11C]CO-Labeled Positron Emission Tomography Radioligand [11C]BIO-1819578 for the Detection of O-GlcNAcase Enzyme Activity. ACS chemical neuroscience. 2023
  • Sangram Nag, Ryosuke Arakawa, Zhisheng Jia, Erik Lachapelle, Lei Zhang, Kevin Maresca, Laigao Chen, Mahabuba Jahan, Timothy Mccarthy, Christer Halldin. Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP). Molecules (Basel, Switzerland). 2023. 28. 12
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MISC (36):
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Lectures and oral presentations  (46):
  • PETおよび[18F]FMeNER-D2を用いたうつ病患者におけるベンラファキシン徐放剤のノルエピネフリントランスポーター占有率
    (第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会 2018)
  • Quantitative evaluation of the Mediso high resolution PET/CT system LFER150 using non-human primate brain imaging.
    (Annual Congress of the European-Association-of-Nuclear Medicine 2018 2018)
  • Quantitative evaluation of the Mediso high resolution PET/CT system LFER150 using non-human primate brain imaging.
    (Annual Congress of the European-Association-of-Nuclear Medicine 2018 2018)
  • Quantification of [11C]PBR28 using venous blood sampling and population-based input function approach as less invasive method.
    (Neuroreceptor Mapping 2018 2018)
  • Target occupancy study and whole body dosimetry with a MAGL PET ligand [11C]PF-06809247 in nonhuman primates.
    (Neuroreceptor Mapping 2018 2018)
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Education (2):
  • 2004 - 2008 日本医科大学大学院精神・行動医学分野
  • 1993 - 1999 日本医科大学医学部
Work history (7):
  • 2021/04 - 日本医科大学 薬理学教室 教授
  • 2019/10 - 2021/03 日本医科大学 精神医学教室 准教授
  • 2014/04 - 2019/09 Karolinska Institutet Department of Clinical Neuroscience Assistant Professor
  • 2012/07 - 2014/03 国立精神・神経医療研究センター 精神保健研究所成人精神保健研究部 認知機能研究室長
  • 2010/04 - 2012/06 厚生労働省 社会・援護局障害保健福祉部精神・障害保健課 心の健康づくり対策官
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Awards (1):
  • 2009/11 - ベーリンガーインゲルハイム社 第46回 (2009年度)ベルツ賞1等賞「精神疾患-うつ病,統合失調症など-」 「精神疾患-うつ病,統合失調症など-」
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