Rchr
J-GLOBAL ID:201901001229916396   Update date: Apr. 12, 2024

Manabu Niimi

ニイミ マナブ | Manabu Niimi
Affiliation and department:
Job title: Assistant Professor
Research field  (2): Experimental pathology ,  Pathobiochemistry
Research keywords  (7): Arteriosclerosis ,  Atherosclerosis ,  Lipoprotein metabolism ,  Dyslipidemia ,  Hyperlipidemia ,  Knockout rabbits ,  Transgenic rabbits
Research theme for competitive and other funds  (7):
  • 2023 - 2027 Effects of ANGPTLs on dyslipidemia and atherosclerosis: analysis using gene-modified rabbits.
  • 2023 - 2026 Elucidation of IDOL inhibition effects on hyperlipidemia and atherosclerosis using KO rabbits
  • 2023 - 2026 Elucidation of the pathogenesis of aortic disease and organ damage by angioscopy using a genetically modified rabbit model
  • 2020 - 2023 Functions of apo A-V in atherosclerosis: a study of knockout rabbit model
  • 2017 - 2020 Function of apoE in lipoprotein metabolism and atherosclerosis: insight from apoE-deficient rabbit model
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Papers (38):
  • Sui Y, Jiang R, Niimi M, Wang X, Xu Y, Zhang Y, Shi Z, Suda M, Mao Z, Fan J, et al. Gut bacteria exacerbates TNBS-induced colitis and kidney injury through oxidative stress. Redox Biol. 2024. 72. 103140
  • Chen Y, Niimi M, Zhang L, Tang X, Lu J, Fan J. A Simple Telemetry Sensor System for Monitoring Body Temperature in Rabbits-A Brief Report. Animals. 2023. 13. 10. 1677-1677
  • Jiang R, Sui Y, Hong JNiimi M, Yan Q, Shi Z, Yao J. The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury. Biomolecules. 2023. 13. 1. 143-143
  • Sui Y, Jiang R, Niimi M, Hong J, Yan Q, Shi Z, Yao J. Development of Dietary Thiol Antioxidant via Reductive Modification of Whey Protein and Its Application in the Treatment of Ischemic Kidney Injury. Antioxidants. 2023. 12. 1. 193-193
  • Capua-Shenkar J, Varsano N, Itzhak NR, Kaplan-Ashiri I, Rechav K, Jin X, Niimi M, Fan J, Kruth HS, Addadi L. Examining atherosclerotic lesions in three dimensions at the nanometer scale with cryo-FIB-SEM. Proc Natl Acad Sci U S A. 2022. 119. 34
more...
Patents (2):
  • Method of measuring cholesterol in remnant-like lipoproteins
  • High density lipoprotein-reactive peptides
Books (1):
  • Atherosclerosis: Methods and Protocols
    2022 ISBN:9781071619230
Lectures and oral presentations  (54):
  • Pathological investigations of intracranial atherosclerosis using multiple hypercholesterolemic rabbit models
    (The International Conference on Animal Models for Cardiovascular Disease 2023 2023)
  • Hyperlipidemic rabbit models for the study of atherosclerotic disease
    (The International Conference on Animal Models for Cardiovascular Disease 2023 2023)
  • A novel model for studying hypertriglyceridemia: Apo A-V knockout rabbits
    (The 55th Annual Scientific Meeting of the Japanese Atherosclerosis Society 2023)
  • A novel model for studying human triglycerides metabolism: Apo A-V knockout rabbits
    (The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science 2023)
  • ApoE-null chylomicron remnants exacerbate atherosclerosis in rabbits.
    (The 6th Scientific Meeting of Japan Rabbit Bioscience Association 2023)
more...
Education (3):
  • - 2014 University of Yamanashi Interdisciplinary Graduate School of Medicine and Engineering Department of Human Environment Medical Engineering
  • - 1996 Niigata University Graduate School of Science Department of Biology
  • - 1994 Niigata University Faculty of Science Department of Biology
Professional career (2):
  • Ph. D.
  • MSc
Work history (2):
  • 2017 - 現在 University of Yamanashi Department of Molecular Pathology, Faculty of Medicine Assistant Professor
  • 2012 - 2017 University of Yamanashi Department of Molecular Pathology, Faculty of Medicine Research Assistant Professor
Committee career (2):
  • 2018 - 現在 Japan Rabbit Bioscience Association Board of Director
  • 2016 - 現在 Japan Atherosclerosis Society Councilor
Association Membership(s) (7):
Japan Rabbit Bioscience Association ,  Japanese Association for Laboratory Animal Science ,  The Japanese Society of Pathology ,  The Japanese Biochemical Society ,  American Heart Association ,  European Atherosclerosis Society ,  Japan Atherosclerosis Society
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