Rchr
J-GLOBAL ID：201901001415388510
Update date: Nov. 05, 2024
Handa Tetsuya
ハンダ テツヤ | Handa Tetsuya
Affiliation and department：
Job title：
Research Associate
Research field (1)：
Molecular biology
Research keywords (8)：
空間オミクス解析
, 単一細胞マルチオミクス解析
, オートファジー
, higher-order chromatin structure
, cellular senescence
, live cell imaging
, gene expression
, epigenetics
Research theme for competitive and other funds (2)：
- 2017 - 2020 特定ゲノム領域の可視化とエピゲノム操作を用いた遺伝子発現制御の動態解析
- 2009 - 2011 真核生物DNA複製の分子メカニズム-DNA二重鎖開裂と合成反応の連携機構の解明-
Papers (19)：
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Ioana Olan, Masami Ando-Kuri, Aled J. Parry, Tetsuya Handa, Stefan Schoenfelder, Peter Fraser, Yasuyuki Ohkawa, Hiroshi Kimura, Masako Narita, Masashi Narita. HMGA1 orchestrates chromatin compartmentalization and sequesters genes into 3D networks coordinating senescence heterogeneity. Nature Communications. 2024
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Naoki Goto, Kazuma Suke, Nao Yonezawa, Hidenori Nishihara, Tetsuya Handa, Yuko Sato, Tomoya Kujirai, Hitoshi Kurumizaka, Kazuo Yamagata, Hiroshi Kimura. ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin. Journal of Cell Biology. 2024
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Tetsuya Handa, Akihito Harada, Kazumitsu Maehara, Shoko Sato, Masaru Nakao, Naoki Goto, Hitoshi Kurumizaka, Yasuyuki Ohkawa, Hiroshi Kimura. Author Correction: Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input. Nature protocols. 2023
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Ozawa, H., Kambe, A., Hibi, K., Murakami, S., Oikawa, A., Handa, T., Fujiki, K., Nakato, R., Shirahige, K., Kimura, H., et al. Transient Methionine Deprivation Triggers Histone Modification and Potentiates Differentiation of Induced Pluripotent Stem Cells. Stem cells (Dayton, Ohio). 2023. 41. 3. 271-286
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Olan, I., Handa, T., Narita, M. Beyond SAHF: An integrative view of chromatin compartmentalization during senescence. Current Opinion in Cell Biology. 2023. 83
ｍore...
MISC (2)：
Lectures and oral presentations (11)：
-
特定ゲノム領域の生細胞イメージングとエピゲノム操作による遺伝子発現制御
(第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会 合同年次大会 2019)
-
Multi-ChIL法による少数細胞の複数エピゲノムの同時解析
(第13回日本エピジェネティクス研究会年会 2019)
-
A chromatin integration labeling method enables epigenomic profiling with lower input
(3R&3C Symposium 2018)
-
特定ゲノム領域の生細胞イメージングとエピゲノム操作による遺伝子発現制御
(日本ゲノム編集学会第3回大会 2018)
-
Chromatin integration labeling technology enables low-input epigenomic profiling
(CSHL Meeting, Nuclear Organization & Function 2018)
ｍore...
Education (2)：
- 2006 - 2012 Osaka University Graduate School of Science Department of Biological Sciences
- 2002 - 2006 Osaka University School of Science Department of Biological Sciences
Professional career (1)：
Work history (5)：
- 2020/09 - 現在 Cancer Research UK Cambridge Institute, University of Cambridge Research Associate
- 2018/04 - 2020/09 Tokyo Institute of Techology Cell Biology Center, Institute of Innovative Research Specially Appointed Assistant Professor
- 2016/04 - 2018/03 Tokyo Institute of Techology Cell Biology Center, Institute of Innovative Research Postdoctoral Fellow
- 2014/09 - 2016/03 Tokyo Institute of Techology Graduate School of Bioscience and Biotechnology Postdoctoral Fellow
- 2012/10 - 2014/08 Osaka University Department of Biological Sciences, Graduate School of Science Postdoctoral Fellow
Awards (1)：
- 2020/02 - 東京工業大学 手島精一記念研究賞
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