hosaka Takashi

ホサカタカシ | hosaka Takashi

Affiliation and department：

Research field (1)： Neurology

Research keywords (3)：神経変性疾患 , 筋萎縮性側索硬化症 , RNA編集

Research theme for competitive and other funds (4)：

2021 - 2026 筋萎縮性側索硬化症の治療開発に向けたRNA編集異常を標的とする診断マーカーの開発
2022 - 2023 RNA編集異常がもたらす孤発性ALSの臨床的特徴の解明と新規診断及び治療バイオマーカーの開発
2021 - 2022 細胞外RNAを用いた孤発性ALSの診断バイオマーカー開発
2019 - 2021 The Develpment of biomarker for amyotrophic lateral sclerosis by measuring editing efficiency on extracellular RNA

Papers (19)：

Takashi Hosaka, Hiroshi Tsuji, Shin Kwak. Roles of Aging, Circular RNAs, and RNA Editing in the Pathogenesis of Amyotrophic Lateral Sclerosis: Potential Biomarkers and Therapeutic Targets. Cells. 2023
Takashi Hosaka, Hiroshi Tsuji, Makoto Terada, Yasushi Tomidokoro, Akiko Ishii, Kiyotaka Nakamagoe, Kazuhiro Ishii, Hiroo Terashi, Hitoshi Aizawa, Akira Tamaoka, et al. Glutamine/arginine site-unedited GluA2 mRNA in cerebrospinal fluid as a biomarker for amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry. 2023
Takashi Hosaka, Shintaro Furuno, Makoto Terada, Yumiko Hamano, Kenichi Komatsu, Katsuichiro Okubo, Yasuaki Koyama, Tetsu Suzuki, Hiroshi Tsuji, Akira Tamaoka, et al. Tracheoarterial fistula in a patient with amyotrophic lateral sclerosis successfully managed by overinflation of the tracheostomy tube cuff alone: a case report. Journal of medical case reports. 2023. 17. 1. 65-65
Soichiro Kado, Koji Kamiya, Takashi Hosaka, Tetsuya Kawamura, Kenichi Komatsu, Eiji Kajii, Hideyuki Takahashi, Mayumi Komine, Mamitaro Ohtsuki. Adult invasive meningococcal disease caused by Neisseria meningitidis classified as serogroup B and sequence type 15947. The Journal of dermatology. 2022. 50. 4. e129-e130
Takashi Hosaka, Makoto Terada, Katsuichiro Okubo, Satoshi Iwabuchi, Eiji Kajii. Management of a rare case of metronidazole-induced encephalopathy presenting as posterior reversible encephalopathy syndrome: a case report. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022

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MISC (48)：

角総一郎, 神谷浩二, 小宮根真弓, 大槻マミ太郎, 保坂孝史, 河村哲也, 小松憲一, 梶井英治. 紫斑を契機に診断に至った侵襲性髄膜炎菌感染症の1例. 日本皮膚科学会雑誌. 2022. 132. 7. 1676-1676
大窪勝一朗, 山下圭輔, 水谷太郎, 寺田真, 保坂孝史, 中山健, 川上ユミ, 永盛美紀子, 渡邊尚寛, 飯田みどり, et al. 米国救命士協会内科救急AMLS(Advanced Medical Life Support)コース開催. 茨城県救急医学会雑誌. 2022. 45. 86-86
大内翔悟, 石井亜紀子, 高橋華, 塩谷彩子, 保坂孝史, 松岡亮太, 武田勇人, 三橋泉, 清水眸, 辻浩史, et al. 10年以上生存した小児発症と成人発症MELASの2剖検例の比較. 臨床神経学. 2021. 61. Suppl. S296-S296
大内翔悟, 高橋華, 寺田真, 保坂孝史, 吉井與志彦, 玉岡晃. 進行性核上性麻痺様の症状で発症し、水頭症を呈したクリプトコッカス髄膜脳炎の76歳男性例. 日本内科学会関東地方会. 2020. 657回. 52-52
武田勇人, 石井亜紀子, 野原誠太郎, 保坂孝史, 儘田直美, 寺田真, 塩谷彩子, 奥根祥, 遠坂直希, 三宅善嗣, et al. 肺小細胞癌を背景とした傍腫瘍性神経症候群の異なる臨床病型をとった4例. 臨床神経学. 2019. 59. Suppl. S280-S280

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Lectures and oral presentations (15)：

カフ過膨張による圧迫止血のみで対処した気管腕頭動脈瘻の1例
(茨城県救急医学会 2021)
Total extracellular RNA levels in cerebrospinal fluid derived from amyotrophic lateral sclerosis
(2021)
ADAR2 downregulation is a cause of death not only in ALS motor neurons but also in cultured cells
(2020)
肝膿瘍に対するメトロニダゾール内服中に可逆性後部白質脳症を呈した87歳女性例
(第654回日本内科学会関東地方会 2019)
ADAR2-mediated A-to-I sites in extracellular RNAs as a biomarker of amyotrophic lateral sclerosis.
(2018)

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Work history (2)：

2023/07 - 現在筑波大学医学医療系脳卒中予防・治療学講師
2019/04 - 2023/06 University of Tsukuba Faculty of Medicine

Awards (2)：

2023/10 - Ibaraki Medical Association Ibaraki Prefectural Medical Contents Award
2023/05 - Award for oral presentation (Clinical research) for JSN member

Association Membership(s) (5)：

日本生化学学会 , 日本認知症学会 , Society for Neuroscience , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , JAPANESE SOCIETY OF NEUROLOGY

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