Research theme for competitive and other funds (1)：
2020 - 2022 Investigation into the novel regulatory mechanism of transcription factor TEAD through lysine acylations
Papers (5)：
Masaki Kikuchi, Shohei Takase, Tsuyoshi Konuma, Kota Noritsugu, Saaya Sekine, Takahisa Ikegami, Akihiro Ito, Takashi Umehara. GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 43. e2304103120
Kota Noritsugu, Takehiro Suzuki, Kosuke Dodo, Kenji Ohgane, Yasue Ichikawa, Kota Koike, Satoshi Morita, Takashi Umehara, Kenji Ogawa, Mikiko Sodeoka, et al. Lysine long-chain fatty acylation regulates the TEAD transcription factor. Cell Reports. 2023. 42. 4. 112388-112388
Saaya Sekine, Shohei Takase, Runa Hayase, Kota Noritsugu, Yuki Maemoto, Yasue Ichikawa, Kenji Ogawa, Yasumitsu Kondoh, Hiroyuki Osada, Minoru Yoshida, et al. Identification of a derivative of the alkaloid emetine as an inhibitor of the YAP-TEAD interaction and its potential as an anticancer agent. Bioscience, biotechnology, and biochemistry. 2023. 87. 5. 501-510
Yuuta Fujikawa, Kenta Terakado, Sayaka Nezu, Kota Noritsugu, Yuki Maemoto, Akihiro Ito, Hideshi Inoue. Improving reactivity of naphthalimide-based GST probe by imparting TPP cation: Development and application for live cell imaging. Bioorganic & Medicinal Chemistry Letters. 2023. 80. 129109-129109
Food additive induced post-translational modifications.
(The 96th Annual Meeting of the Japanese Biochemical Society 2023)
Lysine long-chain fatty acylation regulates TEAD transcription factors in Hippo signaling pathway
(FUTURE DRUG DISCOVERY Empowered by Chemical Biology 2023)
