Rchr
J-GLOBAL ID：201901002290251425
Update date: Oct. 28, 2024
Sakaue Hiroaki
サカウエ ヒロアキ | Sakaue Hiroaki
Affiliation and department：
Research field (1)：
Nutrition and health science
Research keywords (3)：
加齢性疾患
, 老化
, D-アミノ酸
Research theme for competitive and other funds (4)：
- 2020 - 2024 皮膚バリア機能の維持・向上に対する遊離D-アミノ酸の役割
- 2019 - 2023 精神的健康増進を目指した太陽光による中枢作用の解明
- 2016 - 2020 Investigation of isomerization mechanism of aspartic acid involved in the development of cataract
- 2016 - 2016 白内障の病態解明を指向したD-アミノ酸含有タンパク質の新規合成方法の開発
Papers (25)：
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Hiroaki Sakaue, Atsushi Kuno. isoAsp-Quest: Workflow development for isoAsp identification using database searches. Journal of biochemistry. 2024
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Chiaki Nagai-Okatani, Daisuke Tominaga, Azusa Tomioka, Hiroaki Sakaue, Norio Goda, Shigeru Ko, Atsushi Kuno, Hiroyuki Kaji. GRable version 1.0: A software tool for site-specific glycoform analysis with improved MS1-based glycopeptide detection with parallel clustering and confidence evaluation with MS2 information. Molecular & cellular proteomics : MCP. 2024. 100833-100833
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Yuki Yamaguchi, Kentaro Ishii, Sachiko Koizumi, Hiroaki Sakaue, Takahiro Maruno, Mitsuko Fukuhara, Risa Shibuya, Yasuo Tsunaka, Aoba Matsushita, Karin Bandoh, et al. Glycosylation of recombinant adeno-associated virus serotype 6. Molecular therapy. Methods & clinical development. 2024. 32. 2. 101256-101256
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Takahiro Hiono, Hiroaki Sakaue, Azusa Tomioka, Hiroyuki Kaji, Michihito Sasaki, Yasuko Orba, Hirofumi Sawa, Atsushi Kuno. Combinatorial Approach with Mass Spectrometry and Lectin Microarray Dissected Site-Specific Glycostem and Glycoleaf Features of the Virion-Derived Spike Protein of Ancestral and γ Variant SARS-CoV-2 Strains. Journal of proteome research. 2024. 23. 4. 1408-1419
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Shiho Tanaka, Hiroaki Sakaue, Toshikazu Koiwai, Natsuki Okuda, Katsuki Okuyama, Yoshihiko Horioka, Yasunari Hiramatsu, Makoto Kawashima, Naoko Ishiguro, Takashi Sato. Near-infrared radiation causes sebaceous gland enlargement along with an ROS-dependent augmentation of epidermal growth factor receptor expression in hamsters. Experimental dermatology. 2023
ｍore...
MISC (5)：
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奥山勝揮, 坂上弘明, 坂上弘明, 佐藤隆. 近赤外線による温度上昇は皮脂腺のMMP産生を増強する. 日本フォトダーマトロジー学会学術大会講演要旨集. 2023. 6th
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水野 晃治, 竹田 秀友, 上阪 恵太, 坂上 弘明, 林 伸和, 佐藤 隆. 心理的ストレスによる毛包内カテコールアミンの発現調節. 日本香粧品学会誌. 2020. 44. 3. 217-217
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Suzuki Yui, Sakaue Hiroaki, Fujii Noriko. 3 Analysis of aspartyl isomers in skin protein by LC-MS(General Session,The 39^<th> Annual Meeting of the SSOEL-Japan Program). Viva origino. 2014. 42. 3-3
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Sakaue Hiroaki, Fujii Noriko. 19 Inversion of aspartyl residues in _γD-Crystallin from human cataract lens(Symposium 2,The 36^<th> annual meeting of the SSOEL-JAPAN (Abstracts)). Viva origino. 2011. 39. 19-19
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Yuhei Mori, Kenzo Aki, Tadatoshi Kinouchi, Takehiro Kawaguti, Masashi Kida, Hiroaki Sakaue, Noriko Fujii. Simultaneous racemization and glycation of amino acid residues in proteins in UVB irradiated skin. the First International Congress of D-Amino Acid Research. 2009
Books (3)：
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The Importance of the Idea of "Parachirality" in Life Science.
2017
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D-Amino acid residues in proteins related to aging and age-related diseases and a new analysis of the isomers in proteins.
2016
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Behaviors of Mutant Mice Lacking D-Amino-Acid Oxidase Activity.
2016
Education (2)：
- 2011 - 2014 Kyoto University
- 2009 - 2011 Kyoto University
Professional career (1)：
Work history (4)：
- 2021/04 - 現在 National Institute of Advanced Industrial Science and Technology
- 2017/04 - 2021/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
- 2016/04 - 2017/03 International University of Health and Welfare School of Pharmacy
- 2014/04 - 2016/03 International University of Health and Welfare School of Pharmacy
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