Research theme for competitive and other funds (4)：
2017 - 2020 幹細胞技術と遺伝子編集技術を組み合わせアルツハイマー病治療戦略を洗練させる
2014 - 2017 γ-セクレターゼ非依存的なβAPP膜内切断機構の解析
2013 - 2016 Identification of molecules related to modulation of Amyloid beta production in human cerebrospinal fluid (CSF)
2011 - 2014 アルツハイマー病に関連する新規APLP2由来脳脊髄液中ペプチドの解析
Papers (29)：
Kanta Yanagida, Riki Maruyama, Shinji Tagami, Takashi Kudo, Masayasu Okochi, Akio Fukumori. APLP2 is predominantly cleaved by β-secretase and γ-secretase in the human brain. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2023. 23. 2. 311-318
Noriko Marutani, Shoshin Akamine, Daisuke Kanayama, Shiho Gotoh, Kanta Yanagida, Riki Maruyama, Kohji Mori, Tesshin Miyamoto, Hiroyoshi Adachi, Yukako Sakagami, et al. Plasma NfL is associated with mild cognitive decline in patients with diabetes. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2022. 22. 3. 353-359
Hiroyoshi Adachi, Ryohei Yamamoto, Ryohei Fujino, Daisuke Kanayama, Yukako Sakagami, Shoshin Akamine, Noriko Marutani, Kanta Yanagida, Yoshimasa Mamiya, Masaki Koyama, et al. Association of weekday-to-weekend sleep differences and stress response among a Japanese working population: a cross-sectional study. Sleep medicine. 2021. 82. 159-164
Shoshin Akamine, Noriko Marutani, Daisuke Kanayama, Shiho Gotoh, Riki Maruyama, Kanta Yanagida, Yukako Sakagami, Kohji Mori, Hiroyoshi Adachi, Junji Kozawa, et al. Renal function is associated with blood neurofilament light chain level in older adults. Scientific reports. 2020. 10. 1. 20350-20350
Koji Matsuhisa, Atsushi Saito, Longjie Cai, Masayuki Kaneko, Takumi Okamoto, Fumika Sakaue, Rie Asada, Fumihiko Urano, Kanta Yanagida, Masayasu Okochi, et al. Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 1. 865-880
