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J-GLOBAL ID：201901002820119981   Update date: Oct. 08, 2024

Takado Yuhei

Takado Yuhei | Takado Yuhei
Affiliation and department：
National Institutes for Quantum and Radiological Science and Technology

About National Institutes for Quantum and Radiological Science and Technology


Job title： Principal Researcher
Homepage URL  (1)： https://brainenergy.xsrv.jp/
Research field  (2)： Neuroscience - general ,  Neurology
Research keywords  (12)： PET ,  Taurine ,  Alzheimer's Disease ,  Astrocyte ,  Brain energy metabolism ,  Translational Research ,  NanoSIMS ,  Brain metabolism ,  Hyperpolarized MRI ,  Neuroimaging ,  MRS ,  Neurodegenerative diseases
Research theme for competitive and other funds  (7)：
  • 2023 - 2025 Hyperpolarization by UV-induced radicals: developing and characterizing their application in vivo to investigate Alzheimer's disease
  • 2022 - 2025 疼痛の中枢性感作における生体内情報の処理過程に対する動的因果モデルの検証
  • 2022 - 2025 Identification of astrocyte dysfunction molecules involved in the pathogenesis of dementia and elucidation of their mechanisms
  • 2019 - 2023 興奮抑制バランス操作による脳の可塑性メカニズムの理解
  • 2019 - 2022 E/I balance disruption in tau-related dementia
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Papers (86)：
  • Hironobu Endo, Maiko Ono, Yuhei Takado, Kiwamu Matsuoka, Manami Takahashi, Kenji Tagai, Yuko Kataoka, Kosei Hirata, Keisuke Takahata, Chie Seki, et al. Imaging α-synuclein pathologies in animal models and patients with Parkinson's and related diseases. Neuron. 2024
  • Kosei Hirata, Kiwamu Matsuoka, Kenji Tagai, Hironobu Endo, Harutsugu Tatebe, Maiko Ono, Naomi Kokubo, Yuko Kataoka, Asaka Oyama, Hitoshi Shinotoh, et al. In Vivo Assessment of Astrocyte Reactivity in Patients with Progressive Supranuclear Palsy. Annals of neurology. 2024
  • Takahiro Hirao, Mitsuhiro Miyamae, Daisuke Matsuyoshi, Ryuto Inoue, Yuhei Takado, Takayuki Obata, Makoto Higuchi, Naotsugu Tsuchiya, Makiko Yamada. A neuroimaging dataset during sequential color qualia similarity judgments with and without reports. 2024
  • Manabu Kubota, Hironobu Endo, Keisuke Takahata, Kenji Tagai, Hisaomi Suzuki, Mitsumoto Onaya, Yasunori Sano, Yasuharu Yamamoto, Shin Kurose, Kiwamu Matsuoka, et al. In vivo PET classification of tau pathologies in patients with frontotemporal dementia. Brain Communications. 2024
  • Kiwamu Matsuoka, Kosei Hirata, Naomi Kokubo, Takamasa Maeda, Kenji Tagai, Hironobu Endo, Keisuke Takahata, Hitoshi Shinotoh, Maiko Ono, Chie Seki, et al. Investigating neural dysfunction with abnormal protein deposition in Alzheimer's disease through magnetic resonance spectroscopic imaging, plasma biomarkers, and positron emission tomography. NeuroImage. Clinical. 2023. 41. 103560-103560
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MISC (57)：
  • 松岡究, 松岡究, 平田浩聖, 小久保奈緒美, 前田貴雅, 互健二, 遠藤浩信, 高畑圭輔, 篠遠仁, 篠遠仁, et al. Magnetic resonance spectroscopic imaging enables spatial mapping of decreased cerebral glutamate levels associated with tau depositions in Alzheimer’s disease. 日本生物学的精神医学会(Web). 2023. 45th
  • 矢内凜, 南久松丈晴, 下條雅文, 高堂裕平, 佐原成彦, 樋口真人. Rosa26ノックイン型タウ過剰発現マウスを用いたタウオパチーにおける神経炎症応答解析. 日本神経化学会大会抄録集(Web). 2022. 65th
  • 下條雅文, 南久松丈晴, 高橋真奈美, 田桑弘之, 松下有美, 矢内凛, 湊原圭一郎, 小野麻衣子, 高堂裕平, 張明栄, et al. rTg4510認知症モデル動物脳における炎症性アストロサイト病態の画像解析. 日本神経化学会大会抄録集(Web). 2022. 65th
  • 小野麻衣子, 高橋真奈美, 下沢明希, 藤永雅之, 森若菜, 永井裕司, 三村喬生, 熊田勝志, 下條雅文, 高堂裕平, et al. α-synuclein病変の蓄積・伝播を生体脳で可視化する分子プローブの開発. Dementia Japan. 2021. 35. 4
  • 橋本聡華, 前田純, 田桑弘之, 高堂裕平, 下條雅文, 高橋真奈美, 三平和明, 熊田勝志, 稲次基希, 張明栄, et al. てんかん病態におけるアストロサイト機能異常とトリプトファン代謝異常. 日本てんかん外科学会プログラム・抄録集. 2020. 43rd
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Patents (1)：
Education (1)：
  • 1995 - 2001 Niigata University Faculty of Medicine
Professional career (1)：
  • 医学博士 (新潟大学)
Work history (10)：
  • 2022/07 - 現在 National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Principal Researcher
  • 2020/10 - 現在 National Institutes for Quantum and Radiological Science and Technology Department of Functional Brain Imaging Research, Brain Disorder Translational Research Group Principle Researcher
  • 2015/10 - 現在 放射線医学総合研究所(現・量子科学技術研究開発機構) 脳機能イメージング研究部 研究員
  • 2011 - 2015 EPFL
  • 2010 - 2011 スイス連邦工科大学ローザンヌ校 スイス政府奨学金留学生/博士研究員
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Association Membership(s) (9)：
JAPANESE SOCIETY FOR MAGNETIC RESONANCE IN MEDICINE ,  JAPANESE SOCIETY OF NUCLEAR MEDICINE ,  国際タウリン研究会 ,  臨床MR脳機能研究会 ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  JAPAN SOCIETY FOR DEMENTIA RESEARCH ,  JAPANESE SOCIETY OF NEUROLOGY ,  ISMRM
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