Rchr
J-GLOBAL ID：201901003149453509
Update date: May. 01, 2024
Kenji Toyonaga
トヨナガ ケンジ | Kenji Toyonaga
Affiliation and department：
Research field (2)：
Immunology
, Oral medicine (pathology)
Research theme for competitive and other funds (5)：
- 2023 - 2026 Functional analysis of the signaling adaptor protein during oral candidiasis
- 2020 - 2023 抗酸菌感染初期におけるCARD9依存的な宿主防御応答の解析
- 2018 - 2020 A novel regulatory mechanism of C-type lectin receptor-mediated antifungal immunity
- 2016 - 2019 新規結核菌受容体を介した免疫応答活性化機構の解明
- 2014 - 2016 機能未知のC型レクチンが認識する結核菌由来脂質の同定とその機能の解明
Papers (12)：
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Noriyuki Tomiyasu, Masatomo Takahashi, Kenji Toyonaga, Sho Yamasaki, Takeshi Bamba, Yoshihiro Izumi. Efficient lipidomic approach for the discovery of lipid ligands for immune receptors by combining LC-HRMS/MS analysis with fractionation and reporter cell assay. Analytical and bioanalytical chemistry. 2023
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Jun-Ichi Nagao, Sari Kishikawa, Honami Tanaka, Kenji Toyonaga, Yuka Narita, Kanae Negoro-Yasumatsu, Sonoko Tasaki, Ken-Ichi Arita-Morioka, Jiro Nakayama, Yoshihiko Tanaka. Pathobiont-responsive Th17 cells in gut-mouth axis provoke inflammatory oral disease and are modulated by intestinal microbiome. Cell reports. 2022. 40. 10. 111314-111314
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Ei'ichi Iizasa, Yasushi Chuma, Takayuki Uematsu, Mio Kubota, Hiroaki Kawaguchi, Masayuki Umemura, Kenji Toyonaga, Hideyasu Kiyohara, Ikuya Yano, Marco Colonna, et al. TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation. Nature communications. 2021. 12. 1. 2299-2299
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Masahiro Nagata, Kenji Toyonaga, Eri Ishikawa, Shojiro Haji, Nobuyuki Okahashi, Masatomo Takahashi, Yoshihiro Izumi, Akihiro Imamura, Koichi Takato, Hideharu Ishida, et al. Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors. The Journal of experimental medicine. 2021. 218. 1
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Zakaria Omahdi, Yuto Horikawa, Masamichi Nagae, Kenji Toyonaga, Akihiro Imamura, Koichi Takato, Takamasa Teramoto, Hideharu Ishida, Yoshimitsu Kakuta, Sho Yamasaki. Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR. The Journal of biological chemistry. 2020. 295. 17. 5807-5817
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MISC (37)：
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中上 昌信, 永尾 潤一, 岸川 咲吏, 豊永 憲司, 加地 英美, 岩沼 青葉, 吉永 泰周, 坂上 竜資, 田中 芳彦. 歯周病の病態形成を制御する腸内細菌の役割の解明. Journal of Oral Biosciences Supplement. 2023. 2023. [P2-27]
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岩沼 青葉, 豊永 憲司, 永尾 潤一, 岸川 咲吏, 加地 英美, 中上 昌信, 岡 暁子, 田中 芳彦. ミュータンス連鎖球菌によって誘導される免疫応答の解析. Journal of Oral Biosciences Supplement. 2023. 2023. [P1-29]
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岸川 咲吏, 永尾 潤一, 豊永 憲司, 加地 英美, 中上 昌信, 岩沼 青葉, 田崎 園子, 根来 香奈江, 田中 芳彦. 口腔感染症による脳への神経免疫学的影響の解析. Journal of Oral Biosciences Supplement. 2023. 2023. [P2-32]
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豊永 憲司, 永尾 潤一, 田崎 園子, 加地 英美, 岸川 咲吏, 中上 昌信, 岩沼 青葉, 根来 香奈江, 田中 芳彦. Candida albicans口腔感染における免疫受容体シグナル関連分子の役割. Journal of Oral Biosciences Supplement. 2023. 2023. [P3-21]
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永尾 潤一, 中上 昌信, 岸川 咲吏, 豊永 憲司, 加地 英美, 岩沼 青葉, 根来 香奈江[安松], 田崎 園子, 田中 芳彦. 口腔と腸管の免疫ネットワークによる歯周病の病態形成機構. Journal of Oral Biosciences Supplement. 2023. 2023. [P3-26]
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Patents (4)：
Professional career (1)：
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