Rchr
J-GLOBAL ID：201901003313648510   Update date: Jul. 01, 2024

Fukuda Seiji

Fukuda Seiji | Fukuda Seiji
Affiliation and department：
Sugiyama Jogakuen University School of Nursing Department of Nursing

About Sugiyama Jogakuen University School of Nursing Department of Nursing


Research field  (1)： Fetal medicine/Pediatrics
Research keywords  (4)： inherited metabolic disease ,  chemo resistance ,  acute myeloid leukemia ,  hematopoietic stem cells
Research theme for competitive and other funds  (24)：
  • 2024 - 2028 薬剤耐性FLT3/ITD+細胞の「FLT3阻害剤依存性増殖」に対する治療戦略
  • 2022 - 2026 外国にルーツを持つ子どものヘルスリテラシー向上を目指すシステム構築
  • 2022 - 2025 医療安全文化醸成度と関連要因に関する研究
  • 2021 - 2024 Identification of prospective resistant AML clones against FLT3 inhibitor
  • 2016 - 2020 ゲノム編集スクリーニングを用いた急性骨髄性白血病に対する新たな治療標的分子の探索
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Papers (153)：
  • Seiji Fukuda, Nozomi Matsuda, Tsukimi Shoji, Chie Onishi, Tomohiro Hirade, Takeshi Taketani, Louis M. Pelus. The magnitude of CXCR4 signaling regulates resistance to quizartinib in FLT3/ITD+ cells via RUNX1. Leukemia Research. 2022. in press
  • Yoshimitsu Osawa, Hironori Kobayashi, Go Tajima, Keiichi Hara, Kenji Yamada, Seiji Fukuda, Yuki Hasegawa, Junko Aisaki, Miori Yuasa, Ikue Hata, et al. The frequencies of very long-chain acyl-CoA dehydrogenase deficiency genetic variants in Japan have changed since the implementation of expanded newborn screening. Molecular genetics and metabolism. 2022. 136. 1. 74-79
  • Rina TSUCHIE, Satoko AIKA, Seiji FUKUDA. Factors Associated with Self-Esteem in Junior High School Students. Shimane Journal of Medical Science. 2021. 38. 111-118
  • 松田 真一朗, 荒木 もも子, 大西 千恵, 福田 誠司, 鬼形 和道, 竹谷 健. SNRPN遺伝子のDNAメチル化検査でモザイクパターンを示したAngelman症候群の一例. 日本遺伝カウンセリング学会誌. 2021. 42. 2. 54-54
  • 遠藤 進一, 廣瀬 昌博, 内田 絵美子, 石飛 和歌子, 福田 誠司. 地方大学病院における医療安全文化醸成度に関する調査. 日本医療マネジメント学会雑誌. 2021. 22. Suppl. S144-S144
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MISC (82)：
  • Chie Onishi, Satomi Mori-Kimachi, Tomohiro Hirade, Mariko Abe, Takeshi Taketani, Junji Suzumiya, Toshitsugu Sugimoto, Seiji Yamaguchi, Reuben Kapur, Seiji Fukuda. Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis (vol 289, pg 31053, 2014). JOURNAL OF BIOLOGICAL CHEMISTRY. 2015. 290. 47. 28356-28356
  • Seiji Fukuda, Mariko Abe, Tomohiro Hirade, Seiji Yamaguchi. DISRUPTING CDKN1A SECONDARY TO FLT3/ITD INHIBITION IS RESPONSIBLE FOR RESISTANCE TO FLT3/ITD INHIBITOR AC220 IN FLT3/ITD+ CELLS. EXPERIMENTAL HEMATOLOGY. 2015. 43. 9. S63-S63
  • Seiji Fukuda, Chie Onishi, Tomohiro Hirade, Mariko Abe, Takeshi Taketani, Seiji Yamaguchi. Flt3/ITD Enhances Hematopoietic Cell Migration Towards Chemokine CCL2 Independent of Blocking the Negative Feedback Mechanism on Rho-Associated Kinase. BLOOD. 2014. 124. 21
  • Tomohiro Hirade, Mariko Abe, Chie Onishi, Seiji Yamaguchi, Seiji Fukuda. Flt3/ITD Confers Resistance to FLT3 Inhibitor AC220 By up-Regulating Runx1. BLOOD. 2014. 124. 21
  • Pratibha Singh, Seiji Fukuda, Mary R. Saunders, Louis M. Pelus. Survivin Is a Master Regulator of Mesenchymal Stem Cell Functions and Potential Therapeutic Target for Mesenchymal Stem Cell Expansion. BLOOD. 2014. 124. 21
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Lectures and oral presentations  (33)：
  • たんぱく質摂取が体力向上へ及ぼす好ましい影響
    (第51回椙山フォーラム 体をつくる栄養素たんぱく質を知ろう 2024)
  • The FLT3 Inhibitor Quizartinib Augments Migration to the Chemokine CXCL12 and Proliferation in Quizartinib-Resistant FLT3/ITD+ Cells by Upregulating Runx1 Expression
    (10th Translational Research Conference: Myeloproliferative Neoplasms | ESH - European School of Haematology 2024)
  • 白血病の病態と新しい治療法
    (第91回島根大学サイエンスカフェ 2019)
  • FLT3阻害剤耐性の分子機構
    (Acute Myeloid Leukemia Expert Meeting 2019)
  • FLT3/ITD抑制剤に対する抵抗性獲得のメカニズム
    (ゾスパタ新発売記念講演会 2019)
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Education (2)：
  • 1989 - 1993 GIFU University Graduate School of Medicine Graduate School of Medicine Pediatrics
  • 1982 - 1988 GIFU University School of Medicine
Professional career (1)：
  • MD, PhD (GIFU University)
Work history (14)：
  • 2022/04 - 現在 Sugiyama Jogakuen University School of Nursing Department of Nursing professor
  • 2020/04 - 2022/03 Division of Patient Safety, Shimane University Hospital professor
  • 2016/04 - 2020/03 SHIMANE Univeristy School of Medicine Clinical Nursing professor
  • 2008/07 - 2016/03 SHIMANE University School of Medicine Department of Pediatrics associate professor
  • 2007/07 - 2008/06 SHIMANE University Hospital PEDIATIRCS Lecturer/associate professor
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Committee career (8)：
  • 2023/04 - 現在 鳥取大学医学部附属病院 医療安全に関する外部監査委員(委員長)
  • 2021/04 - 2023/03 鳥取大学医学部附属病院 医療安全に関する外部監査委員(委員長)
  • 2016 - 2019 日本学術振興会 科学研究費委員会専門委員 (審査員:胎児医学 小児科成育学関連)
  • 2011 - 2013 日本小児科学会 選挙管理委員
  • 2012 - 2012 公益信託日本白血病研究基金 審査委員(小児科分野)
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Awards (8)：
  • 2022/03 - 島根大学医学部附属病院 島根大学附属病院長表彰 医療安全管理業務
  • 2019/03 - 日本医療秘書学会 日本医療秘書学会 日野原重明賞 医師事務作業補助者が大学病院の医療安全向上に及ぼす効果
  • 2015/11 - 日本小児血液がん学会 日本小児血液がん学会 優秀ポスター賞 Flt3/ITDの阻害はCdkn1a発現を抑制し、Flt3/ITD阻害薬抵抗性細胞の発生を促す
  • 2013/03 - 川野小児医学財団 第13回小児川野医学賞 小児基礎医学分野 造血幹細胞の機能解析に基づく、小児白血病の病態解明と治療開発
  • 2012/04 - ASPR Best Research Award ITD-Flt3 Regulates CXCR4 Signaling Pathways Functionally Distinct From Normal Hematopoietic Cells
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Association Membership(s) (5)：
International Society of Experimental Hematology ,  The American Society of Hematology ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  JAPAN PEDIATRIC SOCIETY
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