Rchr
J-GLOBAL ID：201901003941909013   Update date: Jun. 10, 2024

Sekizawa Shin-ichi

セキザワ シンイチ | Sekizawa Shin-ichi
Affiliation and department：
-

About -


Research field  (1)： Physiology
Research theme for competitive and other funds  (3)：
  • 2022 - 2026 Are changes in the properties of nucleus tractus solitarius inhibitory interneurons during postnatal development a risk factor for sudden infant death syndrome?
  • 2021 - 2024 Research on novel therapeutic targets for nasal allergy
  • 2020 - 2023 自律神経とその幹細胞に着目した抗がん剤の遅発性心毒性の病態解明
Papers (65)：
  • Akitoshi Chikamoto, Ryota Tochinai, Shin-Ichi Sekizawa, Masayoshi Kuwahara. Plasticity occurs in a specific phenotype of neurons in the nucleus tractus solitarius of dystrophin gene-mutated rats. The European journal of neuroscience. 2023
  • Ryota Tochinai, Koichi Kimura, Takeru Saika, Wataru Fujii, Hiroyuki Morita, Koki Nakanishi, Yoshiharu Tsuru, Shin-Ichi Sekizawa, Keitaro Yamanouchi, Masayoshi Kuwahara. Ivabradine ameliorates cardiomyopathy progression in a Duchenne muscular dystrophy model rat. Experimental animals. 2023
  • Ryota Tochinai, Yoshiyasu Nagashima, Shin-Ichi Sekizawa, Masayoshi Kuwahara. Anti-tumor and cardiotoxic effects of microtubule polymerization inhibitors: The mechanisms and management strategies. Journal of applied toxicology : JAT. 2023
  • Haruka Orihara, Min Ma, Yoshiyasu Nagashima, Ryota Tochinai, Shin-Ichi Sekizawa, Daiki Kato, Masahiro Shinada, Susumu Aoki, Naoki Fujita, Takayuki Nakagawa, et al. Co-administration of JQ1, a bromodomain-containing protein 4 inhibitor, enhances the antitumor effect of combretastatin A4, a microtubule inhibitor, while attenuating its cardiotoxicity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023. 160. 114353-114353
  • Yoshiyasu NAGASHIMA, Ryota TOCHINAI, Shin-ichi SEKIZAWA, Daiki KATO, Takayuki NAKAGAWA, Yoshiharu TSURU, Yasuko TATEWAKI, Tatsushi MUTOH, Yasuyuki TAKI, Masayoshi KUWAHARA. Pretreatment with tadalafil attenuates cardiotoxicity induced by combretastatin A4 disodium phosphate in rats. Journal of Toxicologic Pathology. 2023
ｍore...
MISC (30)：
  • 関澤 信一. Biological Academic Topics 鼻アレルギー時のくしゃみ反射増悪に延髄は関与するか?. アレルギーの臨床. 2023. 43. 9. 730-733
  • 関澤 信一. 鼻アレルギーに対し延髄は新規治療ターゲットになるか?. アレルギーの臨床. 2023. 43. 5. 360-363
  • 関澤 信一. 鼻アレルギーに対し延髄は新規治療ターゲットになるか?. アレルギーの臨床. 2023. 43. 5. 360-363
  • 庄子 岳, 栃内 亮太, 関澤 信一, 桑原 正貴. マウスの不安関連行動に及ぼすイムノバイオティクスの影響. 日本獣医学会学術集会講演要旨集. 2022. 165回. [I1A-09]
  • Yoshiyasu NAGASHIMA, Ryota TOCHINAI, Yoshiharu TSURU, Shin-ichi SEKIZAWA, Masayoshi KUWAHARA. Pretreatment of phosphodiesterase type 5 inhibitor attenuates combretastatin A4 disodium phosphate derived myocardial damage in rats. The Journal of Toxicological Sciences (J.Toxicol. Sci.). 2022. 47. Supplement. S348
ｍore...
Books (1)：
  • バイオロジクスの開発と品質・安全性確保
    エル・アイ・シー 2018
Education (1)：
  • 1992 - 1996 The University of Tokyo Graduate School of Agricultural and Life Sciences Department of Veterinary Medical Sciences
Work history (3)：
  • 2016/10 - 現在 東京大学大学院農学生命科学研究科
  • 2012/02 - 2016/09 (独)医薬品医療機器総合機構
  • 2001/04 - 2012/01 カリフォルニア大学デイビス校
Association Membership(s) (3)：
THE JAPANESE SOCIETY OF TOXICOLOGY ,  THE JAPANESE SOCIETY OF VETERINARY SCIENCE ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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