Rchr
J-GLOBAL ID：201901004609601800
Update date: Apr. 13, 2024
Shimada Mihoko
Shimada Mihoko
Affiliation and department：
Other affiliations (1)：
-
National Center for Global Health and Medicine
Research field (1)：
Genetics
Research theme for competitive and other funds (5)：
- 2023 - 2026 Childhood adversity, genetic risk and health outcomes: An epidemiological study of rural Vietnamese adults
- 2022 - 2026 DNAメチル化異常がもたらすナルコレプシー発症機構の解明
- 2021 - 2024 長鎖シークエンス法によるスプライシングバリアント関連多型の解析と疾患研究への応用
- 2021 - 2024 フェノムワイド関連解析及び日本人特異的変異による過眠症の分子基盤の解明
- 2018 - 2021 Elucidation of the mechanism of neurodegeneration in narcolepsy by cross-tissue genome-wide methylation analysis
Papers (33)：
-
Mihoko Shimada, Yosuke Omae, Akiyoshi Kakita, Ramil Gabdulkhaev, Yuki Hitomi, Taku Miyagawa, Makoto Honda, Akihiro Fujimoto, Katsushi Tokunaga. Identification of region-specific gene isoforms in the human brain using long-read transcriptome sequencing. Science advances. 2024. 10. 4. eadj5279
-
Kugui Yoshida-Tanaka, Mihoko Shimada, Yoshiko Honda, Akihiro Fujimoto, Katsushi Tokunaga, Makoto Honda, Taku Miyagawa. Narcolepsy type I-associated DNA methylation and gene expression changes in the human leukocyte antigen region. Scientific reports. 2023. 13. 1. 10464-10464
-
Hanna M Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina M Yogeshwar, Ryan P Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, et al. Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nature communications. 2023. 14. 1. 2709-2709
-
Taku Miyagawa, Susumu Tanaka, Mihoko Shimada, Noriaki Sakai, Kotomi Tanida, Nozomu Kotorii, Tatayu Kotorii, Yu Ariyoshi, Yuji Hashizume, Kimihiro Ogi, et al. A rare genetic variant in the cleavage site of prepro-orexin is associated with idiopathic hypersomnia. npj Genomic Medicine. 2022. 7. 1
-
Hiroki Kiyose, Hidewaki Nakagawa, Atsushi Ono, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuaki Chayama, Mihoko Shimada, Jing Hao Wong, et al. Comprehensive analysis of full-length transcripts reveals novel splicing abnormalities and oncogenic transcripts in liver cancer. PLoS genetics. 2022. 18. 8. e1010342
ｍore...
MISC (7)：
-
音羽健司, 嶋多美穂子, 川上憲人, 堤明純. 日本人産業集団を対象とした遺伝的リスクスコアを用いた不安・うつ状態の予測. 日本不安症学会学術大会プログラム・抄録集. 2022. 14th
-
田中優多, 大井一高, 大井一高, 音羽健司, 嶋多美穂子, 嶋多美穂子, 棚橋俊介, 貝谷久宣, 西村文親, 佐々木司, et al. Discrimination between panic disorder and healthy subjects by polygenic scores for psychiatric disorders and intermediate phenotypes using machine learning. 日本生物学的精神医学会(Web). 2022. 44th
-
Takeshi Otowa, Mihoko Shimada, Norito Kawakami, Akizumi Tsutsumi. GENOME-WIDE GENE-ENVIRONMENT STUDY OF DEPRESSION IN JAPANESE EMPLOYEES. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019. 29. 1193-1193
-
Takeshi Otowa, Mihoko Shimada-Sugimoto, Taku Miya-gawa, Yoshiya Kawamura, Chihiro Kakiuchi, Tadashi Umekage, Kiyoto Kasai, Katsushi Tokunaga, Tsukasa Sasaki. GENOME-WIDE METHYLATION ANALYSIS OF DEPRESSION IN THE JAPANESE POPULATION. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017. 27. S289-S290
-
M. Honda, T. Miyagawa, H. Miyadera, S. Tanaka, M. Kawashima, M. Shimada, Y. Honda, K. Tokunaga. ABNORMALLY LOW SERUM ACYLCARNITINE IN NARCOLEPSY PATIENTS. SLEEP. 2010. 33. A269-A270
ｍore...
Professional career (1)：
Work history (3)：
- 2019/12 - 2021/03 The University of Tokyo
- 2016/10 - 2019/11 Japan Society for the Promotion of Science
- 2015/04 - 2016/09 Japan Society for the Promotion of Science
Return to Previous Page
