Kai Hisahiro

カイヒサヒロ | Kai Hisahiro

Affiliation and department：
Other affiliations (1)：

University of Miyazaki Center for Collaborative Research & Community Cooperation

Research field (2)： Pharmaceuticals - health and biochemistry , Environmental and pharmaceutical development resources

Research keywords (13)：ものとり , 美白化粧品 , Mass Spectrometry , NMR , 漢方 , 生薬 , Direct-Injection Electron Ionization-Mass Spectrometry , Lichen , Blueberry , Adult T-cell Leukemia (ATL) , Melanin , Cucurbitaceae , Metabolomics

Research theme for competitive and other funds (4)：

2024 - 2025 核磁気共鳴(NMR)装置による宮崎県産農産物・加工物の産地判別の技術研究
2021 - 2024 脂肪細胞の低酸素ストレス抑制による生活習慣病予防
2021 - 2022 生薬の品質評価法を「量」から「質」に転換する分析システムの開発
2017 - 2020 Establishment of method for predicting pharmacological activity of plants containing proanthocyanidins based on metabolomics

Papers (46)：

Toru Takeguchi, Hisahiro Kai, Michika Takeshita, Maho Miura, Kenjirou Ogawa, Kazuo Nishiyama, Masao Yamasaki. Koji Mold-derived Lipids Disrupt the Intracellular Redox State by Decreasing the GPx4 and Intracellular Glutathione Levels, Promoting Membrane Lipid Peroxidation, and Inducing Ferroptosis in HL-60 Cells. Journal of Oleo Science. 2024. 73. 7. 991-999
KAI Hisahiro, YAMAMOTO Mio, KAKU Yuto, SHIMIZU Reia, KINOSHITA Kaoru, HARADA Hiroshi. Classification Method for Lichen Species Using EI-MS. Lichenology. 2023. 22. 1・2. 84-84
甲斐久博, 杉田千泰, 植沢芳広, 安藤孝, 山本成郎, 黒川昌彦. 芍薬の薬理活性予測システム実現を目指したNMRメタボロミクスの構築(第2報). 日本生薬学会年会講演要旨集. 2022. 68回. 138-138
Hisahiro Kai, Yoshihito Okada, Yo Goto, Takayuki Nakayama, Kazuhiro Sugamoto, Kenjirou Ogawa, Masao Yamasaki, Kazuhiro Morishita, Koji Matsuno, Hisato Kunitake. Prediction of the Adult T-Cell Leukemia Inhibitory Activity of Blueberry Leaves/Stems Using Direct-Injection Electron Ionization-Mass Spectrometry Metabolomics. Plants (Basel, Switzerland). 2022. 11. 10
Hisahiro Kai, Kazuhiro Sugamoto, Saki Toshima, Yo Goto, Takayuki Nakayama, Kazuhiro Morishita, Hisato Kunitake. Effective Utilization of Vaccinium virgatum Aiton Stems as Functional Materials: Major Constituent Analysis and Bioactivity Evaluation. Plants (Basel, Switzerland). 2022. 11. 4

ｍore...

MISC (11)：

竹口徹, 竹下美愛, 三浦真帆, 小境敏揮, 甲斐久博, 小川健二郎, 西山和夫, 西山和夫, 山崎正夫, 山崎正夫. Induction of cell death of leukemia cells by lipid extracts from koji mold. 日本生物工学会大会講演要旨集. 2022. 74th
木上佑晟, 藤井健斗, 太田優磨, 國武久登, 菅本和寛, 甲斐久博, 荒川輝晃, 西山和夫, 山崎正夫. ブルーベリー葉抽出物による抗肥満効果の検討および活性成分の探索. 日本栄養・食糧学会大会講演要旨集. 2019. 73rd
H. Kai, A. Maeda, Y. Uesawa, Y. Okada, K. Morishita, K. Matsuno. Search for bioactive components from Ephedra species against adult T-cell leukemia using electron ionization MS- and NMR-based metabolomics. PLANTA MEDICA. 2016. 82
福田枝里子, 市川裕司, 中野元生, 馬場正樹, 植沢芳広, 甲斐久博, 松野康二, 岡田嘉仁. 混合物解析の天然素材への応用(第20報) EI-MSを用いたカンゾウ地上部の解析. 日本生薬学会年会講演要旨集. 2015. 62回. 192-192
市川裕司, 中野元生, 福田枝里子, 馬場正樹, 植沢芳広, 奥山徹, 甲斐久博, 松野康二, 笠原義正, 岡田嘉仁. 混合物解析の天然素材への応用(第19報)-EI-MSを用いたトリカブト・ニリンソウ等の解析例-. 日本薬学会年会要旨集(CD-ROM). 2015. 135th. ROMBUNNO.27PB-PM234S

ｍore...

Patents (1)：

細胞増殖抑制剤、医薬品及び食品組成物、並びに製造法

Books (5)：

薬学領域の食品衛生化学
廣川書店 2020 ISBN:9784567472128
薬の生体内運命改訂8版
ネオメディカル 2019 ISBN:9784904634257
(Title is Japanese)
Hirokawa Publishing Co. 2017 ISBN:9784567476706
(Title is Japanese)
Neomedical 2017 ISBN:9784904634219
(Title is Japanese)
Neomedical 2015 ISBN:9784904634127

Education (3)：

2003 - 2007 Meiji Pharmaceutical University Graduate School of Pharmaceutical Sciences
2001 - 2003 Meiji Pharmaceutical University Graduate School of Pharmaceutical Sciences
1997 - 2001 Meiji Pharmaceutical University Faculty of pharmaceutical sciences Department of Pharmacy

Professional career (2)：

博士(薬学) (明治薬科大学大学院)
修士(薬学) (明治薬科大学大学院)

Work history (5)：

2024/04 - 現在 Kyushu University of Medical Science Department of Pharmaceutical Health Sciences, School of Pharmaceutical Sciences Associate Professor
2019/04 - 2024/03 Kyushu University of Health and Welfare Department of Pharmaceutical Health Sciences, School of Pharmaceutical Sciences Associate Professor
2013/04 - 2019/03 Kyushu University of Health and Welfare Department of Pharmaceutical Health Sciences, School of Pharmaceutical Sciences, Lecturer
2008/10 - 2013/03 Kyushu University of Health and Welfare Department of Pharmaceutical Health Sciences, School of Pharmaceutical Sciences Associate Researcher
2007/04 - 2008/09 Miyazaki Prefectural Industrial Support Foundation Research Promotion Bureau for Collaboration of Regional Entities Technical Staff

Committee career (3)：

2023/04 - 2026/03 宮崎県立五ヶ瀬中等教育学校, 文部科学省指定新時代に対応した高等学校改革推進事業 (創造的教育方法実践プログラム) 運営指導委員
2019/04 - 2022/03 宮崎県立五ヶ瀬中等教育学校文部科学省指定地域との協働による高等学校教育改革推進事業(グローカル型)運営指導委員
2015/04 - 2020/03 みやざきCOC+ 地元定着推進室委員

Awards (7)：

2023/07 - 第60回化学関連支部合同九州大会優秀発表賞ブルーベリー葉と茎の熱水抽出物の分離・分析とATL細胞増殖抑制効果
2019/11 - The Pharmaceutical Society of Japan, Kyushu Branch Academic Encouragement Award Prediction of pharmacological activity of natural materials based on metabolomics
2018/02 - 14th Academic relationship conference of Junsei President Award
2016/03 - The 1st Miyazaki COC+, Miyazaki Academic and Science Hills Research Meeting Grand Prize Comparison of Cultivars and Seasonal Variation in Blueberry (Vaccinium Species) Leaf Extract on Adult T-Cell Leukemia Cell Line Growth Suppression
2015/03 - The 135th Annual Meeting of the Pharmaceutical Society of Japan, Excellent Presentation Award Application of Mixture Analysis to Crudo Material from Natural Resources(XIX) -Analysis of Aconitum spp. and Anemone spp. by EI-MS

Show all

Association Membership(s) (8)：

日本質量分析学会 , 日本HTLV-1学会 , THE JAPANESE SOCIETY FOR LICHENOLOGY , The Society of Medicinal Plant and Natural Product Research (GA) , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE SOCIETY OF PHARMACOGNOSY , THE JAPANESE SOCIETY FOR VIROLOGY

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page