Usui Ryota

ウスイリョウタ | Usui Ryota

Research field (3)： Physical and health education , Metabolism and endocrinology , Metabolism and endocrinology

Research keywords (4)：膵β細胞 , インクレチン , インスリン分泌 , 糖尿病

Research theme for competitive and other funds (3)：

2020 - 2022 Single-Cell Transcriptome Analysis of the Replicating Process of Pancreatic Beta Cells
2020 - 2022 Regulation of insulin secretion by carbonic anhydrase 8 (Car8) in pancreatic beta cells
2019 - 2021 Investigation of the function of STIM in pancreatic b-cells

Papers (26)：

Hitoshi Kuwata, Daisuke Yabe, Kenta Murotani, Yuuka Fujiwara, Takuya Haraguchi, Sodai Kubota, Saki Kubota-Okamoto, Ryota Usui, Minori Ishitobi, Yuji Yamazaki, et al. Effects of glucagon-like peptide-1 receptor agonists on secretions of insulin and glucagon and gastric emptying in Japanese individuals with type 2 diabetes: A prospective, observational study. Journal of diabetes investigation. 2021. 12. 12. 2162-2171
龍岡久登, 坂本智子, 矢部大介, 大谷大輔, Ainur Botagarova, 徳本信介, Fauzi Muhammad, 臼井亮太, 小倉雅仁, 渡辺亮, et al. 単細胞トランスクリプトーム解析による膵β細胞増殖過程の遺伝子発現解析. 糖尿病. 2021. 64. Suppl.1. I-1
Yuta Fujiwara, Shunsuke Yamane, Norio Harada, Eri Ikeguchi-Ogura, Ryota Usui, Toshihiro Nakamura, Kanako Iwasaki, Kazuyo Suzuki, Daisuke Yabe, Yoshitaka Hayashi, et al. Carbonic anhydrase 8 (CAR8) negatively regulates GLP-1 secretion from enteroendocrine cells in response to long-chain fatty acids. American journal of physiology. Gastrointestinal and liver physiology. 2021. 320. 4. G617-G626
Daisuke Otani, Takaaki Murakami, Takeshi Matsubara, Masato Hojo, Takuro Nakae, Koki Moriyoshi, Akihiro Yasoda, Ryota Usui, Hisato Tatsuoka, Masahito Ogura, et al. Acromegaly accompanied by diabetes mellitus and polycystic kidney disease. Endocrine journal. 2021. 68. 1. 103-110
Hisato Tatsuoka, Satoko Sakamoto, Daisuke Yabe, Ryotaro Kabai, Unyanee Kato, Tatsuya Okumura, Ainur Botagarova, Shinsuke Tokumoto, Ryota Usui, Masahito Ogura, et al. Single-Cell Transcriptome Analysis Dissects the Replicating Process of Pancreatic Beta Cells in Partial Pancreatectomy Model. iScience. 2020. 23. 12. 101774-101774

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MISC (13)：

徳本信介, 矢部大介, 龍岡久登, 臼井亮太, 後藤久典, ファウジ・ムハンマド, ボタガロバ・アイヌラ, 小倉雅仁, 稲垣暢也. 細胞周期可視化蛍光プローブFucci2aRを用いた膵β細胞増殖の新規定量法の開発. 糖尿病. 2019. 62. Suppl.1. S-105
臼井亮太, 矢部大介, Fauzi Muhammad, Botagarova Ainur, 後藤久典, 徳本信介, 龍岡久登, 田原裕美子, 小林静香, 真鍋俊也, et al. 膵β細胞におけるGPR40シグナルに注目したストア依存性カルシウム流入の意義の解明. 糖尿病. 2019. 62. Suppl.1. S-105
龍岡久登, 矢部大介, 坂本智子, 渡辺亮, 徳本信介, ボタガロワ・アイヌラ, 臼井亮太, 後藤久典, ファウジ・ムハンマド, 小倉雅仁, et al. RNAシークエンスとATACシークエンスを用いた,加齢における膵β細胞増殖能低下のメカニズムの解析. 糖尿病. 2019. 62. Suppl.1. S-120
後藤久典, 臼井亮太, 矢部大介. GLP-1受容体作動薬の心血管・腎イベントリスクに対する効果. 糖尿病の最新治療. 2019. 10. 2. 92-98
臼井亮太, 矢部大介, 後藤久典, Muhammad Fauzi, 徳本信介, 龍岡久登, 田原裕美子, 小倉雅仁, 稲垣暢也. GPR40シグナルによるグルコース応答性インスリン分泌増強機構膵β細胞における小胞体カルシウムセンサー分子STIM1の機能解明. 糖尿病. 2018. 61. Suppl.1. S-387

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Lectures and oral presentations (9)：

The role of the ER Ca2+ sensor, stromal interaction molecule 1 (STIM1), in GPR40-mediated potentiation of glucose-induced insulin secretion
(54th Annual Meeting of European Association for the Study of Diabetes 2018 2018)
ER Ca2+ sensor, stromal interaction molecule 1 (STIM1) plays an important role in GPR40-mediated potentiation of glucose-induced insulin secretion
(Asia Islet Biology & Incretin Symposium 2018)
ATP and Ca2+ dynamics in pancreatic β-cells: Ex vivo analysis using ATP biosensor GO-ATeam1
(9th Scientific Meeting of the Asian Association for the Study of Diabetes 2017)
Long-term efficacy of GLP-1 receptor agonist liraglutide and remaining beta cell function: Retrospective analysis in Japanese patients with type 2 diabetes
(Asia Islet Biology & Incretin Symposium 2013)
劇症1型糖尿病患者におけるグルカゴン分泌の検討
(第14回日本内分泌学会近畿支部学術集会 2013)

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Education (2)：

2014 - 2018 Kyoto University
2003 - 2009 Kyoto University Faculty of Medicine Department of Medical Science

Work history (5)：

2021/04 - 現在関西電力医学研究所糖尿病研究センター上級特別研究員
2019/04 - 2021/03 Kyoto University
2018/04 - 2019/03 Kyoto University
2011/04 - 2014/03 関西電力病院糖尿病・代謝・内分泌センター特任医員
2009/04 - 2011/03 神戸市立西神戸医療センター初期臨床研修医

Awards (3)：

2018/08 - Asia Islet Biology & Incretin Symposium Poster Award
2017/05 - Asian Association for the Study of Diabetes AASD Investigator Award
2015/06 - Yutaka Seino Award 2014 for Diabetes Research and Medical Cooperation

Association Membership(s) (6)：

European Association for the Study of Diabetes , Asian Association for the Study of Diabetes , JAPAN SOCIETY OF METABOLISM AND CLINICAL NUTRITION , The Japan Endocrine Society , THE JAPAN DIABETES SOCIETY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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