Rchr
J-GLOBAL ID：201901005219716467
Update date: May. 25, 2024
TOSHIO KANNO
カンノ トシオ | TOSHIO KANNO
Affiliation and department：
Research field (3)：
Molecular biology
, Molecular biology
, Immunology
Research theme for competitive and other funds (1)：
- 2021 - 2023 病原体センサーSTINGの活性を制御するT細胞特有の脂質スイッチシステムの解明
Papers (18)：
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Toshio Kanno, Ryo Konno, Masaru Sato, Atsushi Kurabayashi, Keisuke Miyako, Takahiro Nakajima, Satoru Yokoyama, Shigemi Sasamoto, Hikari K Asou, Junichiro Ohzeki, et al. The integration of metabolic and proteomic data uncovers an augmentation of the sphingolipid biosynthesis pathway during T-cell differentiation. Communications biology. 2024. 7. 1. 622-622
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Yasuhiro Kamii, Koji Hayashizaki, Toshio Kanno, Akio Chiba, Taku Ikegami, Mitsuru Saito, Yukihiro Akeda, Toshiaki Ohteki, Masato Kubo, Kiyotsugu Yoshida, et al. IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria. Proceedings of the National Academy of Sciences. 2024. 121. 9
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Toshio Kanno, Keisuke Miyako, Takeru Endo, Satoru Yokoyama, Hikari K Asou, Kazuko Yamada, Osamu Ohara, Toshinori Nakayama, Motoko Y Kimura, Yusuke Endo. ACC1-mediated fatty acid biosynthesis intrinsically controls thymic iNKT cell development. International immunology. 2023
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Yusuke Endo, Toshio Kanno, Takahiro Nakajima, Kazutaka Ikeda, Yoshitaka Taketomi, Satoru Yokoyama, Shigemi Sasamoto, Hikari K. Asou, Keisuke Miyako, Yoshinori Hasegawa, et al. 1-Oleoyl-lysophosphatidylethanolamine stimulates RORγt activity in T H 17 cells. Science Immunology. 2023. 8. 86
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菅野 敏生, 中嶋 隆裕, 池田 和貴, 佐藤 大, 長谷川 嘉則, 川島 祐介, 小原 收, 遠藤 裕介. 活性化CD4T細胞サブセットでの細胞内代謝経路に着目をした網羅的なオミックス解析の研究. 脂質生化学研究. 2023. 65. 230-231
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Lectures and oral presentations (4)：
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Modulation of lipid metabolism by regulating SCD2 activation induced augmentation of anti-viral response.
(2024)
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活性化CD4 T細胞サブセットでの細胞内代謝経路に着目をした網羅的なオミックス解析の研究
(第65回 日本脂質生化学会 2023)
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SCD2-mediated cooperative activation of IRF3-IRF9 regulatory circuit controls type I interferon transcriptome in CD4+ T cells
(The 51st Annual Meeting of the Japanese Society for Immunology 2022)
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Investigation of the mechanism underlying lipid metabolism mediated STING activation
(第31回 Kyoto T Cell Conference (KTCC) 2022)
Education (4)：
- 2015 - 2019 千葉大学 リーディング大学院
- 2015 - 2019 Chiba University, Graduate School of Medical and Pharmaceutical Sciences, Doctor's Course
- 2013 - 2015 Chiba University, Graduate School of Medical and Pharmaceutical Sciences, Master's Course
- 2009 - 2013 Chiba University Faculty of Pharmaceutical Sciences Department of Pharmacy
Awards (3)：
- 2021/12 - Japanese society for immunology Best Presentation Award SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4+ T cells
- 2019/03 - 千葉大学 リーディング大学院 千葉大学 博士課程教育リーディングプログラム 優秀学生賞
- 2019/02 - 第三回 Annual Symposium for the Center for Mucosal Immunology, Allergy and Vaccine Development Travel awards for early career investigators
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