Takeuchi Yasuto

Affiliation and department：
Job title：助教

Research field (2)： Molecular biology , Tumor biology

Research keywords (5)： hypoxia , Molecular imaging , Calcium imaging , Cell competition , Epithelial homeostasis

Research theme for competitive and other funds (8)：

2021 - 2026 Elucidation of regulatory mechanisms of cancer stem cell division
2022 - 2025 Novel strategies for the treatment of pral cancerbased on hypoxia assessment
2022 - 2024 Novel diagnostic strategy for refractory osteomyelitis of the jaw by hypoxia molecular imaging
2019 - 2022 Novel strategy for treatment of oral cancer based on hypoxia imaging
2016 - 2019 New strategy for oral cancer based on molecular imaging reflecting therapeutic resistance

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Papers (24)：

Mengjiao Li, Tatsunori Nishimura, Yasuto Takeuchi, Tsunaki Hongu, Yuming Wang, Daisuke Shiokawa, Kang Wang, Haruka Hirose, Asako Sasahara, Masao Yano, et al. FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters. The Journal of clinical investigation. 2023. 133. 22
Yuming Wang, Tsunaki Hongu, Tatsunori Nishimura, Yasuto Takeuchi, Hiroshi Takano, Takiko Daikoku, Ryoji Yao, Noriko Gotoh. Mitochondrial one-carbon metabolic enzyme MTHFD2 facilitates mammary gland development during pregnancy. Biochemical and biophysical research communications. 2023. 674. 183-189
楠木啓主, 本宮綱記, 西村建徳, 竹内康人, 岡本康司, 後藤典子. 乳がん細胞はミトコンドリア内1炭素代謝酵素MTHFD1Lを用いて肺転移を起こす(Mitochondrial one-carbon metabolic enzyme MTHFD1L contributes to breast cancer lung metastasis). 日本癌学会総会記事. 2023. 82回. 979-979
本宮綱記, 楠木啓主, Wang Yuming, 西村建徳, 竹内康人, 後藤典子. 乳がん細胞はミトコンドリア内1炭素代謝酵素MTHFD1Lを用いた肺転移を起こす. Cytometry Research. 2023. 33. Suppl. 81-81
Yasuto Takeuchi, Noriko Gotoh. Inflammatory cytokine-enriched microenvironment plays key roles in the development of breast cancers. Cancer Science. 2023. 114. 5. 1792-1799

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MISC (7)：

Yasuto Takeuchi, Natsuko Kimura, Takahiko Murayama, Yukino Machida, Daisuke Iejima, Tatsunori Nishimura, Yuming Wang, Mizuki Yamamoto, Naoki Itano, Junichiro Inoue, et al. FRS2b fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis. CANCER SCIENCE. 2022. 113. 994-994
竹内康人, 犬伏正幸, 村井知佳, 秦浩信, 北川善政. さまざまな低酸素条件における低酸素応答領域による遺伝子発現の評価. 日本口腔科学会雑誌. 2014. 63. 4. 420-420
犬伏正幸, 三輪建太, 青木伊知男, 辻厚至, 竹内康人, 我妻慧, 村田泰輔, 宮原信幸, 佐賀恒夫, 小泉満, et al. 新しい固有同期法を用いた小動物用CTによる左室機能評価. JSMI Rep. 2014. 7. 2. 75-75
Yasuto Takeuchi, Masayuki Inubushi, Yong-Nan Jin, Kotaro Nagatsu, Chika Murai, Atsushi Tsuji, Hironobu Hata, Yoshimasa Kitagawa, Tsuneo Saga. Simultaneous PET/SPECT imaging to compare tumor uptake level of 18F-FMISO with 64Cu-ATSM on the basis of the genetic activation level responding to tumor hypoxia. JOURNAL OF NUCLEAR MEDICINE. 2014. 55
竹内康人, 犬伏正幸, 村井知佳, 秦浩信, 北川善政, 佐賀恒夫. Na+/I-共輸送タンパクを用いた低酸素応答の分子遺伝子イメージング. 核医学. 2012. 49. 3. S196-S196

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Work history (7)：

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