KITADOKORO Kengo

Affiliation and department：

Research field (2)： Pharmaceuticals - analytical and physicochemistry , Structural biochemistry

Research keywords (4)：ドラッグデザイン , 毒素 , 構造生物学 , X線結晶構造解析

Research theme for competitive and other funds (18)：

2016 - 2019 Structural studies of a new cesium ion scavenger using a toxin having molecular switch ability
2013 - 2015 パスツレラ毒素によるヘテロ3量体Gタンパク質のシグナル伝達活性化機構の構造的基盤
2011 - 2013 毒素タンパク質のシグナル伝達活性化メカニズムの構造的基盤
2011 - 2013 Crystal Structure of Clostridium perfringens Enterotoxin.
2009 - 2011 Fluorescence-signaling and imaging of oxidative stress on the basis of diverse fluorescent proteins originating from luminous bacteria

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Papers (38)：

Kengo Kitadokoro, Yukiko Okuno, Takaaki Hikima, Masaki Yamamoto Shigeki Kamitani. On elucidating the mechanism by which anti-obesity drugs inhibit virulence factors of Staphylococcus aureus. Medical Science Digest. 2023. 49. 11. 486-487
Yukiko Ohara, Yuriko Ozeki, Yoshitaka Tateishi, Tsukasa Mashima, Fumio Arisaka, Yasuo Tsunaka, Yoshie Fujiwara, Akihito Nishiyama, Yutaka Yoshida, Kengo Kitadokoro, et al. Correction: Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis. PloS one. 2021. 16. 8. e0256946
Kengo Kitadokoro, Mutsumi Tanaka, Takaaki Hikima, Yukiko Okuno, Masaki Yamamoto, Shigeki Kamitani. Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat. Scientific reports. 2020. 10. 1. 5469-5469
大原由貴子, 小林悠, 尾関百合子, 西山晃史, 立石善隆, 奥田修二郎, 神谷重樹, 北所健悟, 松本壮吉. 抗酸菌症治療薬を目指した標的蛋白質の発現と精製. 日本細菌学雑誌. 2020. 75. 1. 74-74
北所健悟, 田中睦美, 古澤昌大, 神谷重樹. 構造生物学から観た寄生適応の分子戦略黄色ブドウ球菌由来毒素リパーゼと阻害剤のドラッグデザイン. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [2S06m-06]

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MISC (22)：

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