KITADOKORO Kengo

Affiliation and department：

Research field (2)： Pharmaceuticals - analytical and physicochemistry , Structural biochemistry

Research keywords (4)：ドラッグデザイン , 毒素 , 構造生物学 , X線結晶構造解析

Research theme for competitive and other funds (19)：

2024 - 2027 黄色ブドウ球菌の増殖を根こそぎ断つ抗リパーゼ薬創製のための複合体の結晶構造解析
2016 - 2019 Structural studies of a new cesium ion scavenger using a toxin having molecular switch ability
2013 - 2015 パスツレラ毒素によるヘテロ3量体Gタンパク質のシグナル伝達活性化機構の構造的基盤
2011 - 2013 毒素タンパク質のシグナル伝達活性化メカニズムの構造的基盤
2011 - 2013 Crystal Structure of Clostridium perfringens Enterotoxin.

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Papers (40)：

北所健悟, 奥野友紀子, 引間孝明, 山本雅貴, 神谷重樹. 抗肥満薬が黄色ブドウ球菌の病原因子を阻害するメカニズムを解明. BIO Clinica. 2024. 39. 9. 782-784
Julia Kitadokoro, Shigeki Kamitani, Yukiko Okuno, Takaaki Hikima, Masaki Yamamoto, Takatsugu Hirokawa, Kengo Kitadokoro. Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid. FEBS Open Bio. 2024
Kengo Kitadokoro, Yukiko Okuno, Takaaki Hikima, Masaki Yamamoto Shigeki Kamitani. On elucidating the mechanism by which anti-obesity drugs inhibit virulence factors of Staphylococcus aureus. Medical Science Digest. 2023. 49. 11. 486-487
Yukiko Ohara, Yuriko Ozeki, Yoshitaka Tateishi, Tsukasa Mashima, Fumio Arisaka, Yasuo Tsunaka, Yoshie Fujiwara, Akihito Nishiyama, Yutaka Yoshida, Kengo Kitadokoro, et al. Correction: Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis. PloS one. 2021. 16. 8. e0256946
Kengo Kitadokoro, Mutsumi Tanaka, Takaaki Hikima, Yukiko Okuno, Masaki Yamamoto, Shigeki Kamitani. Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat. Scientific reports. 2020. 10. 1. 5469-5469

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MISC (32)：

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