Research theme for competitive and other funds (3):
2023 - 2024 IL-33放出機構の解明に向けた細胞分泌実時間イメージング解析
2020 - 2022 敗血症モデルにおける計画的ネクローシスのFRETイメージング
2016 - 2019 Live cell imaging of regulated necrosis
Papers (21):
Yuka Inaba, Emi Hashiuchi, Hitoshi Watanabe, Kumi Kimura, Yu Oshima, Kohsuke Tsuchiya, Shin Murai, Chiaki Takahashi, Michihiro Matsumoto, Shigetaka Kitajima, et al. The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice. Nature Communications. 2023. 167
Shin Murai, Kanako Takakura, Kenta Sumiyama, Kenta Moriwaki, Kenta Terai, Sachiko Komazawa-Sakon, Takao Seki, Yoshifumi Yamaguchi, Tetuo Mikami, Kimi Araki, et al. Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis. Communications Biology. 2022. 5. 1. 1331-1331
Shin Murai, Kanako Takakura, Kenta Sumiyama, Kenta Moriwaki, Kenta Terai, Sachiko Komazawa-Sakon, Yoshifumi Yamaguchi, Tetuo Mikami, Kimi Araki, Masaki Ohmuraya, et al. A FRET biosensor, SMART, monitors necroptosis in renal tubular epithelial cells in a cisplatin-induced kidney injury model. 2022
Hiroyasu Nakano, Shin Murai, Kenta Moriwaki. Regulation of the release of damage-associated molecular patterns from necroptotic cells. The Biochemical journal. 2022. 479. 5. 677-685
Osamu Nakabayashi, Hirotaka Takahashi, Kenta Moriwaki, Sachiko Komazawa-Sakon, Fumiaki Ohtake, Shin Murai, Yuichi Tsuchiya, Yuki Koyahara, Yasushi Saeki, Yukiko Yoshida, et al. MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL. Communications biology. 2021. 4. 1. 80-80