Rchr
J-GLOBAL ID：201901005616187144
Update date: May. 15, 2024
Kiwaki Takumi
キワキ タクミ | Kiwaki Takumi
Affiliation and department：
Job title：
Assistant Professor
Research field (1)：
Human pathology
Research theme for competitive and other funds (4)：
- 2023 - 2026 がん細胞の HGF 活性制御分子に着目した HGF-MET 依存性転移機構の解明
- 2020 - 2023 Investigation of activation mechanisms and exploration of inhibition therapy of HGF-MET signal in cancer microenvironment
- 2019 - 2020 ヒト固形がんにおける Patient derived xenograft (PDX) 株の樹立と,それを用いた HGF-MET シグナル標的治療の開発
- がんの転移と細胞接着分子 L1CAM 発現との関連についての臨床病理学的検討
Papers (20)：
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Chihiro Kawasoe, Yoshi Miyamoto, Kaoru Ito, Takaya Murashima, Takahiro Nagai, Hiroki Takamori, Takumi Kiwaki, Toshio Kamimura, Shoichiro Mukai, Toshiyuki Kamoto. Epithelioid Angiomyolipoma with Tumor Thrombus into Inferior Vena Cava Presurgically Treated with Combination Therapy of Pembrolizumab and Axitinib: A Case Report. Research and Reports in Urology. 2023
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Makiko Kawaguchi, Hiroaki Kataoka, Takumi Kiwaki, Liang Weiting, Sayaka Nagata, Kazuo Kitamura, Tsuyoshi Fukushima. Adrenomedullin alleviates mucosal injury in experimental colitis and increases claudin-4 expression in the colonic epithelium. FEBS open bio. 2023
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Fujii M, Akioka T, Kimura S, Nagai T, Kiwaki T, Fukushima T, Mukai S, Kamoto T. Possible role of combined therapy targeting MET and pro-HGF activation for renal cell carcinoma: analysis by human HGF-producing SCID mice. Human cell. 2023. 36. 2. 775-785
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Takumi Kiwaki, Hiroaki Kataoka. Patient-Derived Organoids of Colorectal Cancer: A Useful Tool for Personalized Medicine. Journal of Personalized Medicine. 2022
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Aya Izumi, Koji Yamamoto, Makiko Kawaguchi, Fumiki Yamashita, Tsuyoshi Fukushima, Takumi Kiwaki, Hiroyuki Tanaka, Yoshihiro Yamashita, Hiroaki Kataoka. Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells. Cancer science. 2022
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Lectures and oral presentations (3)：
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Exploration of a novel anti-cancer therapy using patient-derived cancer organoids
(2021)
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ヒト HGF 導入 SCID マウスを用いた HGF-MET シグナル解析と阻害治療の開発
(第38回日本ヒト細胞学会学術集会 2020)
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A synthetic small molecule inhibitor of pro-HGF activation, ZFH7116, suppresses the growth of SAS squamous cell carcinoma line in human HGF knock-in SCID mice: A pilot study
(ASBMB Symposia: Serine Proteases in Pericellular Proteolysis and Signaling 2019)
Education (1)：
- - 2015 University of Miyazaki Faculty of Medicine
Professional career (1)：
Work history (6)：
- 2024/03 - 現在 宮崎大学医学部 病理学講座腫瘍形態病態学分野 助教
- 2021/07 - 2024/02 宮崎大学医学部 病理学講座腫瘍・再生病態学分野 助教
- 2017/04 - 2021/06 宮崎大学医学部 病理学講座腫瘍・再生病態学分野 医員
- 日本病理学会分子病理専門医
- 日本臨床細胞学会細胞診専門医
- 日本病理学会認定病理専門医
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Awards (1)：
- 2020/05 - The Kyushu-Okinawa Branch of the Japanese Society of Pathology Best Case Report Award (Young Pathologist Encouragement Award) from the Kyushu-Okinawa Branch of the Japanese Society of Pathology
Association Membership(s) (4)：
日本ヒト細胞学会
, 日本臨床細胞学会
, 日本癌学会
, 日本病理学会
