Mirai Yamazaki

Affiliation and department：

Research field (3)： Nutrition and health science , Metabolism and endocrinology , Molecular biology

Research theme for competitive and other funds (7)：

2024 - 2027 フルクトースによるミトコンドリア異常機構の解明:肝オルガノイドを用いた新たな試み
2021 - 2024 フルクトースによる代謝障害の分子機構の解明:肝臓オルガノイドを用いた新たな試み
2022 - 2023 希少糖アルロース摂取による抗肥満作用の分子メカニズムの解明
2021 - 2022 敗血症に特徴的に生じる免疫麻痺の分子メカニズムの解明-敗血症モデルマウスを用いた単球miRNA異常の解析-
2020 - 2021 マイクロRNAを標的とした敗血症バイオマーカー開発のための基礎的検討

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Papers (49)：

Mirai Yamazaki, Hiroya Yamada, Eiji Munetsuna, Yoshitaka Ando, Genki Mizuno, Atsushi Teshigawara, Hayato Ichikawa, Yuki Nouchi, Itsuki Kageyama, Takuya Wakasugi, et al. Approaches to nutritional research using organoids; fructose treatment induces epigenetic changes in liver organoids. The Journal of nutritional biochemistry. 2024. 131. 109671-109671
Keisuke Maeda, Ryosuke Fujii, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, et al. Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study. Endocrine journal. 2024
Yoshitaka Ando, Eiji Munetsuna, Hiroya Yamada, Miyuki Ikeya, Atsushi Teshigawara, Itsuki Kageyama, Yuki Nouchi, Takuya Wakasugi, Mirai Yamazaki, Genki Mizuno, et al. Impact of maternal fructose intake on liver stem/progenitor cells in offspring: Insights into developmental origins of health and disease. Life sciences. 2024. 336. 122315-122315
Genki Mizuno, Hiroya Yamada, Yoshiki Tsuboi, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Itsuki Kageyama, Yuki Nouchi, Atsushi Teshigawara, Yuji Hattori, et al. Low mitochondrial DNA copy number in peripheral blood mononuclear cells is associated with future mortality risk: a long-term follow-up study from Japan. The journal of nutrition, health & aging. 2024. 28. 1. 100013-100013
Keisuke Maeda, Hiroya Yamada, Eiji Munetsuna, Ryosuke Fujii, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Yoshiki Tsuboi, Hiroaki Ishikawa, Koji Ohashi, et al. Serum carotenoid levels are positively associated with DNA methylation of thioredoxin-interacting protein. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2023

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Books (1)：

Epigenetics and fructose metabolism: A new mechanism of fructose effects
Elsevier 2019

Lectures and oral presentations (15)：

フルクトース過剰摂取モデルラットの肝オルガノイド作成および遺伝子発現解析
(第94回日本衛生学会学術総会 2024)
Maternal high-fructose corn syrup consumption modulates brain-derived neurotrophic factor expression through epigenetic modification in offspring hippocampus.
(11th World Congress on DOHaD 2019)
Maternal fructose consumption increases susceptibility to stress exposure in offspring.
(2018)
母獣フルクトース摂取による次世代の海馬BDNFの減少とエピジェネティック制御
(2018)
母獣のフルクトース過剰摂取が仔海馬の脳由来神経栄養因子の発現に及ぼす影響
(2018)

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Professional career (1)：

博士 (医療科学)

Work history (4)：

2023/10 - 現在 Fujita Health University
2023/04 - 2023/09 Kagawa Prefectural College of Health Sciences Kagawa Prefectural College of Health Sciences Department of Medical Technology
2019/04 - 2023/03 Kagawa Prefectural College of Health Sciences Kagawa Prefectural College of Health Sciences, Department of Medical Technology
2017/04 - 2019/03 Fujita Health University

Association Membership(s) (4)：

日本衛生学会 , The Japan Endocrine Society , JAPAN SOCIETY OF CLINICAL CHEMISTRY , JAPANESE SOCIETY OF LABORATORY MEDICINE

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