Rchr
J-GLOBAL ID：201901006027076622   Update date: Oct. 28, 2024

Sato Hiromi

Sato Hiromi
Affiliation and department：
Chiba University Lab of Clinical Pharmacology & Pharmacometrics, Graduate School of Pharmaceutical Sciences

About Chiba University Lab of Clinical Pharmacology & Pharmacometrics, Graduate School of Pharmaceutical Sciences


Job title： Associate professor
Research field  (2)： Pharmacology ,  Clinical pharmacy
Research keywords  (17)： cancer drug resistance ,  brain cancer ,  tumor microenvironment ,  astrocyte ,  metabolic flux analysis ,  connexin ,  gap junction ,  metabolome ,  sex differences ,  aging ,  drug-drug interaction ,  modeling and simulation ,  MBMA ,  diabetes mellitus ,  CVR ,  adipose inflammation ,  drug absorption
Research theme for competitive and other funds  (16)：
  • 2023 - 2026 2型糖尿病および慢性心不全に共通する病態解明と治療応用の可能性への助成
  • 2021 - 2024 Significance of ketone body metabolic shift in diabetes and long-term prognosis prediction
  • 2022 - 2023 小腸素過程の相互作用を考慮した薬物吸収の包括的予測モデルの開発
  • 2019 - 2022 薬物相互作用・生理機能変化を踏まえた医薬品の投与最適化の評価・予測手法の開発
  • 2019 - 2021 cGAS-STING 経路のがん進展への関与および治療標的の可能性
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Papers (99)：
  • Hiromi Sato, Ayana Ishikawa, Hideki Yoshioka, Ryota Jin, Yamato Sano, Akihiro Hisaka. Model-based meta-analysis of HbA1c reduction across SGLT2 inhibitors using dose adjusted by urinary glucose excretion. Scientific Reports. 2024
  • Ryota Jin, Hideki Yoshioka, Hiromi Sato, Akihiro Hisaka. Data-driven disease progression model of Parkinson's disease and effect of sex and genetic variants. CPT: pharmacometrics & systems pharmacology. 2024. 13. 4. 649-659
  • Manisha Bhateria, Isha Taneja, Kajal Karsauliya, Ashish Kumar Sonker, Yukihiro Shibata, Hiromi Sato, Sheelendra Pratap Singh, Akihiro Hisaka. Predicting the in vivo developmental toxicity of fenarimol from in vitro toxicity data using PBTK modelling-facilitated reverse dosimetry approach. Toxicology and applied pharmacology. 2024. 484. 116879-116879
  • Yukako Soejima, Hideki Yoshioka, Sayuri Guro, Hiromi Sato, Hiroto Hatakeyama, Yasunori Sato, Yoshihide Fujimoto, Naohiko Anzai, Akihiro Hisaka. Exercise training outcomes in patients with chronic heart failure with reduced ejection fraction depend on patient background. Frontiers in cardiovascular medicine. 2024. 11. 1330235-1330235
  • Sato H, Marutani R, Takaoka R, Mori-Fegan D, Wang X, Maeda K, Kusuhara H, Suzuki H, Yoshioka H, Hisaka A. Model-based meta-analysis of ethnic differences and their variabilities in clearance of oral drugs classified by clearance mechanism. CPT: Pharmacometrics & Systems Pharmacology. 2023. 12. 8. 1132-1142
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MISC (61)：
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Books (3)：
  • 性差医学・医療の進歩と臨床展開Vol.9:薬物動態と薬力学における性差
    医学のあゆみ 2018
  • 薬物代謝の違いを考慮した処方とは? -男女で効果に違いはあるか?-
    ハートレビュー,メディカルレビュー社 2014
  • Chapter 10: Connexin 43 Enhances the Cisplatin-Induced Cytotoxicity in Mesothelioma Cells
    2012
Lectures and oral presentations  (192)：
  • Systematic Prediction of Drug Interactions Integrating In Vivo and In Vitro Information Considering Contributions by Multiple Molecular Species of CYP and Transporter
    (2020)
  • メタボローム特性とがん薬物抵抗性の連関
    (第34回日本薬物動態学会年会 2019)
  • Simultaneous In Vitro Evaluation of Efflux by P-glycoprotein and Metabolism by CYP3A Using CYP3A4-CPR-HAC/Caco-2 Cells
    (第34回日本薬物動態学会年会 2019)
  • Quantitative evaluation of reduced hepatic clearance in elderly people based on meta-analysis of population pharmacokinetic analyses
    (第34回日本薬物動態学会年会 2019)
  • Significance of involvement of multiple molecular species in drug interactions by CYP inhibition.
    (第34回日本薬物動態学会年会 2019)
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Education (3)：
  • 2006 - 2008 Chiba University Graduate School of Pharmaceutical Sciences Ph.D. (Pharmaceutical Sciences)
  • 2004 - 2006 Chiba University Graduate School of Pharmaceutical Sciences Master of Sciences (Medical Pharmacy)
  • 2000 - 2004 Chiba University Faculty of Pharmaceutical Sciences
Professional career (1)：
  • 博士(薬学) (千葉大学)
Work history (4)：
  • 2023/10 - 現在 Chiba University Graduate School of Pharmaceutical Sciences Associate professor
  • 2018/03 - 2023/09 Chiba University Graduate School of Pharmaceutical Sciences Lecturer
  • 2008/04 - 2018/02 Chiba University Graduate School of Pharmaceutical Sciences Assistant professor
  • 2011/04 - 2011/06 The University of British Columbia The Life Sciences Institute(Acceptance: Prof. Christian C. Naus) Visiting scientist
Committee career (9)：
  • 2022/12 - 現在 日本臨床薬理学会 評議員
  • 2022/07 - 現在 日本毒性学会 評議員
  • 2022/03 - 現在 日本性差医学・医療学会 評議員
  • 2013 - 現在 日本薬学会 薬理系薬学部会 若手世話人
  • 2012 - 現在 日本薬理学会 学術評議員
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Awards (6)：
  • 2022/10 - DMPK award 1st place
  • 2022/03 - 日本薬学会 令和3年度日本薬学会 薬理系薬学部会奨励賞 がん治療抵抗性におけるgap junctionの関与
  • 2019/06 - 12th Research Award of Japan Reserch Foundation Clinical Pharmacology
  • 2017/01 - 日本性差医学・医療学会 第10回日本性差医学・医療学会 優秀ポスター賞 NBDレセプト情報オープンデータにみる薬剤提供実態の男女差
  • 2015/03 - 千葉東洋医学シンポジウム 第40回千葉東洋医学シンポジウム 優秀発表賞 更年期障害患者における桂枝茯苓丸治療効果に関するエストロゲン受容体遺伝子多型の関与
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Association Membership(s) (8)：
THE JAPANESE SOCIETY OF TOXICOLOGY ,  American Association for Cancer Research ,  日本性差医学・医療学会 ,  THE JAPANESE SOCIETY OF CLINICAL PHARMACOLOGY AND THERAPEUTICS ,  THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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