HAYASHI Ryuhei

ハヤシリュウヘイ | HAYASHI Ryuhei

Affiliation and department：
Homepage URL (1)： http://www.stemed.med.osaka-u.ac.jp/index-e.html

Research field (3)： Cell biology , Medical biochemistry , Ophthalmology

Research keywords (5)： Eye/Cornea , Regenerative medicine , Epithelial Stem Cells , Organoid , Pluripotent stem cells

Research theme for competitive and other funds (9)：

2022 - 2025 Naive型多能性幹細胞の多分化能修復による分化指向性と眼関連細胞発生機序の解明
2020 - 2023 Elucidation of the mechanism of whole eye development and its reproduction in vitro by regulating scaffold environment using pluripotent stem cells
2019 - 2022 Mechanism of tissue interaction in human eye development.
2017 - 2020 Elucidation of the mechanism of corneal epithelial development using SEAM as human eye development model
2013 - 2018 Elucidation of the pathophysiology and therapeutic development of mechano-stress associated eye diseases such as glaucoma using iPS cells

Show all

Papers (65)：

Masahiro Kitao, Ryuhei Hayashi, Kimihito Nomi, Reiko Kobayashi, Tomohiko Katayama, Hiroshi Takayanagi, Akiko Oguchi, Yasuhiro Murakawa, Kohji Nishida. Identification of BST2 as a conjunctival epithelial stem/progenitor cell marker. iScience. 2023. 26. 7. 107016-107016
Tsutomu Imaizumi, Ryuhei Hayashi, Yuji Kudo, Xiaoqin Li, Kaito Yamaguchi, Shun Shibata, Toru Okubo, Tsuyoshi Ishi, Yoichi Honma, Kohji Nishida. Ocular instillation of conditioned medium from mesenchymal stem cells is effective for dry eye syndrome by improving corneal barrier function. Scientific Reports. 2023
Yu Yoshinaga, Takeshi Soma, Shohei Azuma, Kazuichi Maruyama, Yoshiko Hashikawa, Tomohiko Katayama, Yuzuru Sasamoto, Hiroshi Takayanagi, Naoki Hosen, Takashi Shiina, et al. Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets. Stem Cell Reports. 2022. 17. 7. 1714-1729
Toru Okubo, Ryuhei Hayashi, Yuji Kudo, Yuki Ishikawa, Andrew J. Quantock. Fabrication of three-dimensional lacrimal gland-like tissue organoids from human pluripotent stem cells. 2022
Ryuhei Hayashi, Toru Okubo, Yuji Kudo, Yuki Ishikawa, Tsutomu Imaizumi, Kenji Suzuki, Shun Shibata, Tomohiko Katayama, Sung-Joon Park, Robert D Young, et al. Generation of 3D lacrimal gland organoids from human pluripotent stem cells. Nature. 2022

ｍore...

MISC (28)：

今泉務, 今泉務, 林竜平, 林竜平, 工藤裕司, 工藤裕司, 李小琴, 李小琴, 柴田峻, 柴田峻, et al. 脂肪組織由来間葉系幹細胞の分泌因子によるドライアイ治療薬開発に向けた基礎的検討. 日本再生医療学会総会(Web). 2022. 21st
今泉務, 林竜平, 工藤裕司, 今泉務, 林竜平, 工藤裕司, 李小琴, 柴田峻, 柴田峻, 大久保徹, et al. 間葉系幹細胞由来分泌因子よるドライアイ治療薬開発に向けた基礎的検討. 日本眼薬理学会プログラム・講演抄録集. 2021. 41st
片山朋彦, 林竜平, 大久保徹, 大久保徹, 柴田峻, 柴田峻, 高柳泰, 安川裕子, 山手百合香, 小林由紀, et al. ヒトES,iPS細胞からの角膜上皮細胞の誘導. 日本再生医療学会総会(Web). 2020. 19th
柴田峻, 柴田峻, 林竜平, 工藤裕司, 工藤裕司, 大久保徹, 大久保徹, 今泉務, 今泉務, 片山朋彦, et al. Cell-type-specific adhesion to laminin isoforms and cell competition enable purification of iPS cell-derived corneal epithelium. 日本結合組織学会学術大会抄録集. 2020. 52nd
柴田峻, 柴田峻, 林竜平, 工藤裕司, 工藤裕司, 大久保徹, 大久保徹, 片山朋彦, 石川幸, 小林由紀, et al. iPS角膜上皮シート作製工程の効率化検討-FACSを用いない角膜上皮細胞単離法の開発-. 日本再生医療学会総会(Web). 2019. 18th

ｍore...

Professional career (1)：

Ph.D (Tohoku University)

Association Membership(s) (6)：

日本眼薬理学会 , ARVO , JAPANESE OPHTHALMOLOGICAL SOCIETY , JAPAN CORNEA SOCIETY , International Society for Stem Cell Research , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page