Seki Yuta

Affiliation and department：

Research field (1)： Laboratory animal science

Research keywords (6)：不動毛 , 内耳有毛細胞 , 実験動物学 , 進行性難聴 , 遺伝性難聴 , モデルマウス

Research theme for competitive and other funds (7)：

2020 - 2023 ミオシン6のミスセンス変異ヘテロ型で生じる進行性難聴の遺伝子治療
2018 - 2020 Mechanisms of stereocilia formation defined by myosin vi isoform highly expressed in the inner ear
2015 - 2018 Identification of genetic risk factors and phenotypic rescue of deaf mutant mice based on technological innovations of the forward genetics approach
2015 - 2018 Identification of the functional genomic polymorphisms affecting mouse progressive hearing loss
2015 - 2017 Exploring the function of an inner ear-specific myosin VI isoform

Show all

Papers (18)：

Xuehan Hou, Shumpei P Yasuda, Midori Yamaguchi, Sari Suzuki, Yuta Seki, Takafumi Ouchi, Ting Mao, Ornjira Prakhongcheep, Hiroshi Shitara, Yoshiaki Kikkawa. Impacts of an age-related hearing loss allele of cadherin 23 on severity of hearing loss in ICR and NOD/Shi mice. Biochemical and biophysical research communications. 2023. 674. 147-153
Shumpei P. Yasuda, Yuki Miyasaka, Xuehan Hou, Yo Obara, Hiroshi Shitara, Yuta Seki, Kunie Matsuoka, Ai Takahashi, Eri Wakai, Hiroshi Hibino, et al. Two Loci Contribute to Age-Related Hearing Loss Resistance in the Japanese Wild-Derived Inbred MSM/Ms Mice. Biomedicines. 2022. 10. 9. 2221-2221
Yuta Seki, Hiroshi Shitara, Rie Ishii, Takafumi Ouchi, Shumpei P Yasuda, Yoshiaki Kikkawa. Myosin VI Haploinsufficiency Reduced Hearing Ability in Mice. Neuroscience. 2021. 478. 100-111
Shumpei P Yasuda, Yuta Seki, Sari Suzuki, Yasuhiro Ohshiba, Xuehan Hou, Kunie Matsuoka, Kenta Wada, Hiroshi Shitara, Yuki Miyasaka, Yoshiaki Kikkawa. c.753A>G genome editing of a Cdh23ahl allele delays age-related hearing loss and degeneration of cochlear hair cells in C57BL/6J mice. Hearing research. 2020. 389. 107926-107926
Matsuoka K, Wada K, Miyasaka Y, Yasuda SP, Seki Y, Nishito Y, Yonekawa H, Taya C, Shitara H, Kikkawa Y. OHC-TRECK: A Novel System Using a Mouse Model for Investigation of the Molecular Mechanisms Associated with Outer Hair Cell Death in the Inner Ear. Scientific reports. 2019. 9. 1. 5285

ｍore...

MISC (7)：

関優太, 吉川欣亮. 難聴の遺伝的要因と発症メカニズム-Genetic factors and pathogenic mechanisms of hearing loss-第1土曜特集五感を科学する : 感覚器研究の最前線 ; 聴覚. 医学のあゆみ. 2022. 282. 6. 648-656
吉川欣亮, 関優太, 安田俊平. ミオシンVIハプロ不全に起因する加齢性難聴. バイオサイエンスとインダストリー. 2022. 80. 4
宮坂勇輝, 宮坂勇輝, 設楽浩志, 鈴木沙理, 関優太, 多屋長治, 高田豊行, 城石俊彦, 木南凌, 米川博通, et al. Ush1gヘテロマウスの聴覚障害はCdh23の1塩基置換により回復する. 日本実験動物学会総会講演要旨集. 2016. 63rd. 121
Yuta Seki, Sari Suzuki, Yuki Miyasaka, Kunie Matsuoka, Yoshiaki Kikkawa. Mechanisms underlying hearing impairment associated with heterozygosity of the Myosin VI mutant allele in mice. GENES & GENETIC SYSTEMS. 2014. 89. 6. 334-334
Yuta Seki, Nanako Ikehara, Masaru Fujita, Yoshio Nagura, Mai Kotani, Kou Nomura, Masako Kanno, Takashi Amano, Kenta Wada, Michinari Yokohama, et al. Genome-wide identification of QTL in a cross between Shiba and Saanen goat. GENES & GENETIC SYSTEMS. 2010. 85. 6. 427-427

ｍore...

Education (1)：

Professional career (1)：

Work history (1)：

Association Membership(s) (2)：

日本耳科学会 , 日本実験動物学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page