Kinoshita Manabu

2020 - 2023 ミトコンドリア機能と品質管理機構から捉える重症病態の分子病態研究

2017 - 2023 Compromised hostでの免疫不全の病態解析と高度侵襲対策

2020 - 2022 川崎病血管炎における好中球サブセット動態の解析と重症度予測への応用

2019 - 2022 Efficacy of Infusion with Hemoglobin Vesicles in Rabbits with Massive obstetric Hemorrhage

2019 - 2022 Treatment of trauma induced coagulopathy with H12-ADP-liposome

2019 - 2022 The effect of LPS preconditioning on the lethal mlaria infection

2018 - 2022 Enhanced cellular engraftment of adipose-derived mesenchymal stem cell therapy by Nanosheets.

2018 - 2022 Preventive effect of postoperative liver failure and promotion of liver regeneration after massive hepatectomy by LPS tolerance

2018 - 2021 Novel therapeutic strategy against drug-resistant bacterial sepsis in compromised hosts focusing on enhancing bactericidal activity of macrophages

2017 - 2020 Challenge to Optimize allocation of Pediatric Surgical Resources by using Remote Medical Platform

2017 - 2020 The therapeutic strategy for burn-induced immunosuppression: PPARgamma activation for control of innate immune response

2017 - 2020 Anti-tumor activity in LPS tolerance and development of new technology on clinical application of tolerance

2017 - 2020 Mechanism of augmented phagocytic activity in liver by pioglitazone treatment

2016 - 2019 Combination therapy using fibrinogen gamma-chain peptide-coated, ADP-encapsulated liposomes and hemoglobin vesicles for trauma-induced massive hemorrhage

2016 - 2019 The effect for C-reactive protein (CRP) for sever sepsis

2016 - 2019 The function of Kupffer cells in cholesterol metabolism

2016 - 2019 Development of a new biodegradable magnesium alloy for medical equipment

2015 - 2019 Transplantation of adipose-derived stem cell using the absorbable nanosheet.

2016 - 2018 Development of a next generation photothermal therapy using a light-absorbing drug that selectively accumulates in lesions for pediatric cancer

2015 - 2018 Development of Retained Surgical Gauze Detection System before Closing Surgical Incisions.

2015 - 2018 Photodynamic therapy using nanoparticle loaded with indocyanine green for experimental peritoneal dissemination of gastric cancer

2014 - 2018 Photo dynamic therapy for eradication of Helicobacter pylori

2014 - 2017 Blood purification for sepsis-induced immunoparalysis

2014 - 2017 Novel antioxidant therapy for radiation-induced injuries

2014 - 2017 The therapeutic strategy for burn-induced immunosuppression: Regulation of phagocytes function.

2014 - 2017 Infection control based on photodynamic effect and new treatment for pressure ulcer by promoting wound healing

2013 - 2017 A novel therapeutic approach to severe burns by microskin grafts combined with ultra-thin nanosheets

2013 - 2016 Resveratrol ameliorates high-fat-diet-induced fatty liver by increasing CD68 positive Kupffer cells.

2013 - 2016 The Novel Hemostatic and Tissue Protective Treatment Elucidating the Pathophysiology of Blast Lung Injury

2013 - 2016 Role of the macrophages in non-alcoholic steatohepatitis and impaired glucose tolerance

2013 - 2016 Management against surgical stress in compromised hosts

2012 - 2015 Photodynamic therapy using nanoparticle loaded with indocyanine green for experimental metastasis model of gastric cancer

2011 - 2013 Surgical stress induces immunosuppression and this condition contributes to tumor growth

2011 - 2012 Photodynamic diagnosis and treatment for local multiple-drug-resistant bacterial infection using photosensitizers that preferably accumulate into bacteria.

2011 - 2012 Bacterial pathogen Helicobacter pylori may augment gene expressions of TLR4 and TLR5 on cancer cells under coexistence with another gastric bacteria Proteus mirabilis

2010 - 2012 Mechanical analyses and treatment of immunodeficiency following burn injury