Ohki Shinya

オオキシンヤ | Ohki Shinya

Affiliation and department：
Research theme for competitive and other funds (10)：

2021 - 2026 Studies on molecular mechanism of effector-mediated establishment of host specificity in plant pathogens and their application
2020 - 2023 揺らいだ分子構造の植物病原菌エフェクターDN3の機能発現機構
2021 - 2022 エフェクターに基づく植物病原菌の宿主特異性成立の分子基盤
2018 - 2021 The pathogenic calcification mechanism in the dental pulp through AGEs/RAGE signal pathway elucidated by the imaging mass spectroscopy
2017 - 2020 Structuer-function relationship of CoDN3, an effector of Colletotrichum orbiculare

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Papers (60)：

Naohiko Iguchi, Noriyoshi Isozumi, Yoshikazu Hattori, Tomohiro Imamura, Masatomo So, Hitoki Nanaura, Takao Kiriyama, Nobuyuki Eura, Minako Yamaoka, Mari Nakanishi, et al. Zinc finger domains bind low-complexity domain polymers. 2023
Jing Gu, Noriyoshi Isozumi, Bin Gao, Shinya Ohki, Shunyi Zhu. Mutation-driven evolution of antibacterial function in an ancestral antifungal scaffold: Significance for peptide engineering. Frontiers in Microbiology. 2022. 13
Maiki Tamura, Chiharu Tatsushiro, Eugene Hayato Morita, Shinya Ohki. Structural and functional studies of LaIT2, an antimicrobial and insecticidal peptide from Liocheles australasiae. Toxicon. 2022. 214. 8-17
Tomohiro Imamura, Noriyoshi Isozumi, Yasuki Higashimura, Hironori Koga, Tenta Segawa, Natsumi Desaka, Hiroki Takagi, Kenji Matsumoto, Shinya Ohki, Masashi Mori. Red-Beet Betalain Pigments Inhibit Amyloid-β Aggregation and Toxicity in Amyloid-β Expressing Caenorhabditis elegans. Plant Foods for Human Nutrition. 2022. 77. 1. 90-97
Shunyi Zhu, Bin Gao, Yoshitaka Umetsu, Steve Peigneur, Ping Li, Shinya Ohki, Jan Tytgat. Adaptively evolved human oral actinomyces-sourced defensins show therapeutic potential. EMBO Molecular Medicine. 2021

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MISC (16)：

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Books (4)：

基礎から学ぶ構造生物学第5章「基本的な2次構造を持つタンパク質」
共立出版 2008
Advances in Experimental Medicine and Biology vol.592 (Regulatory Mechanisms of Striated Muscle Contraction) Structural Basis for Calcium Regulated Relaxation of Striated Muscle at Interaction Sites of Troponin with Actin and Tropomyosin
Springer (Eds. S.Ebashi & I.Ohtsuki) 2007
Recent Developments in Stable-Isotope-Aided Mathods for Protein NMR Spectroscopy in Modern Magnetic Resonance (Ed. G.A.Webb)
Springer 2006
「ライフサイエンス系の機器分析」第5章NMR
三共出版 2004

Lectures and oral presentations (27)：

Structure and dynamics of LaIT2, a toxic peptide, from Japanese scorpion, Liocheles australasiae
(60th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan (NMRSJ 2021) 2021)
CoDN3, an Effector of Colletotrichum Orbiculare, Is an IDP (Intrinsically Disordered Protein) That Binds to Calmodulin in a Ca2+ Dependent Manner
(2020)
Structural Modeling Of LaIT2 As A Peptide Toxin In The Venom Of Japanese Scorpion Liocheles australasiae, With Cross Validation Experiments Using Polyclonal Antibodies For LaIT2 And C-LaIT2
(2020)
Solution NMR structure of LaIT2, an antimicrobial peptide of Yaeyama scorpion (Liocheles australasiae)
(2020)
ヤエヤマサソリ由来殺虫性毒素LaIT2のC末端ドメインの大腸菌大量発現系構築と精製方法の確立
(日本生化学会北陸支部第38回大会 2020)

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Professional career (1)：

Association Membership(s) (4)：

日本プロテインホスファターゼ研究会 , 日本核磁気共鳴学会 , 日本タンパク質科学会 , The biophysical society of Japan

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