Sefan Asamitsu

アサミツセファン | Sefan Asamitsu

Affiliation and department：

Research field (5)： Chemical biology , Functional biochemistry , Developmental biology , Molecular biology , Neuroscience - general

Research keywords (4)：非コードゲノム科学 , 神経科学 , ケミカルバイオロジー , 核酸化学

Research theme for competitive and other funds (7)：

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Papers (31)：

Kazuya Matsuo, Sefan Asamitsu, Kohei Maeda, Hiroyoshi Suzuki, Kosuke Kawakubo, Ginji Komiya, Kenta Kudo, Yusuke Sakai, Karin Hori, Susumu Ikenoshita, et al. RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation. Cell. 2024
Deepak Karna, Lin Liang, Grinsun Sharma, Shankar Mandal, Sefan Asamitsu, Yusuke Kawamoto, Kaori Hashiya, Toshikazu Bando, Hiroshi Sugiyama, Hanbin Mao. Modulation of dynamic DNA G-quadruplex structures in the hTERT promoter region by ligands. Nucleic Acids Research. 2024
Kenta Kudo, Karin Hori, Sefan Asamitsu, Kohei Maeda, Yukari Aida, Mei Hokimoto, Kazuya Matsuo, Yasushi Yabuki, Norifumi Shioda. Structural polymorphism of the nucleic acids in pentanucleotide repeats associated with the neurological disorder CANVAS. Journal of Biological Chemistry. 2024. 300. 4. 107138-107138
Susumu Ikenoshita, Kazuya Matsuo, Yasushi Yabuki, Kosuke Kawakubo, Sefan Asamitsu, Karin Hori, Shingo Usuki, Yuki Hirose, Toshikazu Bando, Kimi Araki, et al. A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models. The Journal of clinical investigation. 2023
Kazuya Matsuo, Sefan Asamitsu, Kohei Maeda, Kosuke Kawakubo, Ginji Komiya, Kenta Kudo, Yusuke Sakai, Karin Hori, Susumu Ikenoshita, Shingo Usuki, et al. RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration. bioRxiv. 2023

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MISC (4)：

Patents (1)：

Books (3)：

Brain Science Dictionary
2022
Development of Selective DNA-Interacting Ligands - Understanding the Function of Non-canonical DNA Structures
Springer 2020
Annual Reports in Medicinal Chemistry
2020

Lectures and oral presentations (5)：

Roles of chromatin DNA higher-order structure in mammalian cell
(FIBER Webinar Universe☆Rising Stars 2024)
神経細胞におけるクロマチン核酸高次構造の役割
(日本ケミカルバイオロジー学会第18回年会 2024)
G-quadruplex RNA regulates neuronal function through the functional formation of stress granules
(FIBER Webinar Universe☆Rising Stars 2023)
神経細胞におけるグアニン四重鎖RNAのストレス顆粒形成に与える影響
(第414回発生研セミナー 2023)
神経細胞におけるグアニン四重鎖の役割
(FIBER 核酸化学ユニバースRising Stars 2022)

Education (3)：

Professional career (1)：

Work history (6)：

2023/04 - 現在理化学研究所生命医科学研究センター研究員
2020/04 - 2023/03 日本学術振興会特別研究員 PD
2019/04 - 2020/03 Kumamoto University Institute of Molecular Embryology and Genetics
2017/04 - 2019/03 日本学術振興会特別研究員(DC2)
2017/10 - 2017/11 Nanyang Technological University, visiting scholar (Prof. Anh Tuân Phan)

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Awards (2)：

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