2020 - 2023 Ultra-early detection of gastrointestinal cancer and establishment of on-site adaptive diagnostic methods toward standardization of laser ESD
2019 - 2021 Development of Computational Clinical Trial Mehtod for Laser Medicine
2016 - 2019 Development of infrared laser ionization techniques for high throughput mass spectrometry of membrane proteins
2015 - 2018 Construction of the carious detecter system using the laser
2013 - 2018 Rapid and high resolution molecular imaging with stigmatic imaging mass spectrometry
2013 - 2016 Development of infrared laser atmospheric pressure ionization techniques for high throughput mass spectrometry of membrane proteins
2012 - 2016 Development of selective therapeutic techniques by excitation of molecular vibration using mid-infrared lasers
2011 - 2013 Development of high-throughput measurement techniques of pharmacokinetics using stigmatic imaging mass spectrometry
2007 - 2011 Measurement of organic metabolism using low-energy photons
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Papers (146)：
Sochi J. Ogbonna, Katsuyoshi Masuda, Hisanao Hazama. The effect of fluence rate and wavelength on the formation of protoporphyrin IX photoproducts. Photochemical & Photobiological Sciences. 2024
Sota Kondo, Yutaka Tomioka, Naohiro Fujimoto, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Theoretical Study on the Mechanism of Dentin Hardness Measurement Using a Tooth Hardness Measuring Device with a Light-Emitting Diode. The Journal of Japan Society for Laser Surgery and Medicine. 2024. 45. 2. 127-135
Sota Kondo, Yutaka Tomioka, Naohiro Fujimoto, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Mechanism of dentin hardness measurements using a dentin hardness measuring device with a light-emitting diode. Journal of Biomedical Optics. 2024. 29. 02. 025002-1-025002-14
Sochi J. Ogbonna, William Y. York, Takahiro Nishimura, Hisanao Hazama, Hideo Fukuhara, Keiji Inoue, Kunio Awazu. Increased fluorescence observation intensity during the photodynamic diagnosis of deeply located tumors by fluorescence photoswitching of protoporphyrin IX. Journal of Biomedical Optics. 2023. 28. 5. 055001-1-055001-15
Sota Kondo, Hisanao Hazama, Yutaka Tomioka, Atsushi Mine, Satoshi Yamaguchi, Saeko Okumura, Hiroaki Tanimoto, Kenzo Yasuo, Kazushi Yoshikawa, Kazuyo Yamamoto, et al. Demonstration of an optical dentin hardness measuring device using bovine dentin with different demineralization times. Journal of Biomedical Optics. 2022. 27. 10. 105004-1-105004-13
Computational evaluation of the effect of interstitial PDT with 5-ALA for pretreatment planning (Conference Presentation)
(17th International Photodynamic Association World Congress 2019)
Evaluation of a novel photosensitizing drug having antitumor effect for advanced prostate cancer
(Optics InfoBase Conference Papers 2017)
Hemagglutinating virus of Japan envelope (HVJ-E) allows targeted and efficient delivery of photosensitizer for photodynamic therapy against advanced prostate cancer
(Optical Molecular Probes, Imaging and Drug Delivery, OMP 2015 2015)
Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs measured with a double integrating sphere and inverse monte carlo method
(Optics InfoBase Conference Papers 2013)
Development of selective laser treatment techniques using mid-infrared tunable nanosecond pulsed laser
(2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 2010)
2020/06 - International Phototherapy Association Best Paper Award 2019 of Laser Therapy Photodynamic therapy by lysosomal-targeted drug delivery using talaporfin sodium incorporated into inactivated virus particles
2018/02 - Michael T. Eismann, Editor-in-Chief of Optical Engineering Appreciation for serving as a reviewer awarded to Hisanao Hazama for Optical Engineering during the calendar year of 2017 Presented by Michael T. Eismann, Editor-in-Chief
2018/02 - International Phototherapy Association Prof. Ming Chien Kao Award 2017 of Laser Therapy Evaluation of endovenous laser ablation for varicose veins using a computer simulation model (Secondary publication)
2017/02 - International Phototherapy Association Prof. Ming Chien Kao Award 2016 of Laser Therapy Effective photodynamic therapy in drug-resistant prostate cancer cells utilizing a non-viral antitumor vector (a secondary publication)
2015/02 - International Phototherapy Association Good Paper Award 2014 of Laser Therapy Ex vivo efficacy evaluation of laser vaporization for treatment of benign prostatic hyperplasia using a 300-W high-power laser diode with a wavelength of 980 nm
2013/07 - Poster Award of 4th Asia Oceania Mass Spectrometry Conference and 10th Taiwan Society for Mass Spectrometry Annual Conference Imaging mass spectrometry of pharmaceutical drugs using a high mass resolution MALDI-SpiralTOF
