Junichi Takino

Affiliation and department：

Research field (1)： Molecular biology

Research theme for competitive and other funds (6)：

2021 - 2025 生活習慣病の新規概念「毒性終末糖化産物(Toxic AGEs)原因説」の確立
2018 - 2021 The effects of HNRNPM in pancreatic cancer under the hypovascular environment
2016 - 2020 Generation and accumulation of intracellular toxic advanced glycation end-products due to modern dietary habits and elucidation of relevant cytotoxic mechanisms
2013 - 2016 Association between characteristics of current diet and onset/deterioration of non-alcoholic fatty liver disease
2010 - 2012 1nvolvement of hyperglycemiaand dietary AGEs inthe prevention of life style-related disease

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Papers (43)：

Shouhei Miyazaki, Jun-ichi Takino, Kentaro Nagamine, Takamitsu Hori. RasGRP2 Attenuates Oxygen Deprivation-Induced Autophagy in Vascular Endothelial Cells. Biological and Pharmaceutical Bulletin. 2023. 46. 11. 1512-1516
Masayoshi Takeuchi, Akiko Sakasai-Sakai, Takanobu Takata, Jun-ichi Takino, Yoshiki Koriyama. Effects of Toxic AGEs (TAGE) on Human Health. Cells. 2022. 11. 14. 2178-2178
Jun-Ichi Takino, Shouhei Miyazaki, Kentaro Nagamine, Takamitsu Hori. The Role of RASGRP2 in Vascular Endothelial Cells-A Mini Review. International journal of molecular sciences. 2021. 22. 20
Masayoshi Takeuchi, Akiko Sakasai-Sakai, Takanobu Takata, Jun-ichi Takino, Yoshiki Koriyama, Chigusa Kikuchi, Ayako Furukawa, Kentaro Nagamine, Takamitsu Hori, Tamihide Matsunaga. Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage. Biomolecules. 2021. 11. 3. 387-387
竹内正義, 逆井亜紀子[坂井], 高田尊信, 瀧野純一, 郡山恵樹, 菊池千草, 古川絢子, 長嶺憲太郎, 堀隆光, 松永民秀. 細胞内Toxic AGEs(TAGE)の生成・蓄積は各種細胞障害のトリガーとなる. 日本薬学会年会要旨集. 2021. 141年会. 28P02-235

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MISC (47)：

宮崎翔平, 瀧野純一, 長嶺憲太郎, 堀隆光. RasGRP2 in vascular endothelial cells attenuates HIF-1α-mediated autophagy under hypoxic environment. 日本薬学会年会要旨集(Web). 2024. 144th
瀧野純一, 宮崎翔平, 長嶺憲太郎, 堀隆光. Effect of RASGRP2 on TAGE-induced vascular endothelial dysfunction. 日本薬学会年会要旨集(Web). 2024. 144th
宮崎翔平, 瀧野純一, 長嶺憲太郎, 堀隆光. Effects of RasGRP2 on vascular permeability and HIF degradation system in hypoxic environment. 日本薬学会年会要旨集(Web). 2023. 143rd
高橋のどか, 瀧野純一, 宮崎翔平, 長嶺憲太郎, 堀隆光. Suppression of inflammation-related genes by RASGRP2 in the vascular endothelial cells. 日本薬学会年会要旨集(Web). 2022. 142nd
竹内正義, 逆井(坂井)亜紀子, 高田尊信, 瀧野純一, 郡山恵樹, 古川絢子, 那須隆斗, 菊池千草, 長嶺憲太郎, 堀隆光, et al. Toxic AGEs (TAGE) as a new concept in the lifestyle-related diseases. 日本薬学会年会要旨集(Web). 2022. 142nd

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