Rchr
J-GLOBAL ID：201901008317701957   Update date: Jun. 21, 2024

Oki Hiroya

オキ ヒロヤ | Oki Hiroya
Affiliation and department：
Osaka University Research Institute for Microbial Diseases

About Osaka University Research Institute for Microbial Diseases


Research field  (2)： Structural biochemistry ,  Bacteriology
Research keywords  (5)： X線結晶構造解析 ,  分泌タンパク質 ,  マイナーピリン ,  IV形線毛 ,  腸管系病原菌
Research theme for competitive and other funds  (4)：
  • 2020 - 2023 Genomic survey of enteric pathogens in India for developing anti-adhesion therapies
  • 2020 - 2023 腸管系病原菌が形成するIV型線毛を利用した分泌タンパク質の放出機構解明
  • 2019 - 2021 The mechanism of intestinal colonization by type IV pilus from Vibrio cholerae
  • 2017 - 2019 腸管毒素原性大腸菌(ETEC)の腸管定着機構の解明および定着阻害剤の開発
Papers (22)：
  • Sotaro Fujii, Riku Sakaguchi, Hiroya Oki, Kazuki Kawahara, Tadayasu Ohkubo, So Fujiyoshi, Yoshihiro Sambongi. Contribution of a surface salt bridge to the protein stability of deep-sea Shewanella benthica cytochrome c'. Journal of structural biology. 2023. 215. 4. 108031-108031
  • Ryo Masuda, Khine Phyu Phyu Thant, Kazuki Kawahara, Hiroya Oki, Tetsuya Kadonosono, Yuji Kobayashi, Takaki Koide. A yeast two-hybrid system to obtain triple-helical ligands from combinatorial random peptide libraries. bioRxiv. 2023. https://doi.org/10.1101/2023.11.14.567114
  • Ryujin Miyata, Chie Miyabe, Hiroya Oki, Daisuke Motooka, Shota Nakamura, Yoshishige Miyabe, Yuko Takenaka, Yasuko Fukuya, Kazuo Yudo, Naoko Ishiguro. Alteration of microbial composition in the skin and blood in vasculitis. Scientific reports. 2023. 13. 1. 15317-15317
  • Wakaki Kami, Takeshi Kinjo, Hiroe Hashioka, Wakako Arakaki, Kohei Uechi, Ami Takahashi, Hiroya Oki, Kentaro Tanaka, Daisuke Motooka, Shota Nakamura, et al. Impact of G29179T mutation on two commercial PCR assays for SARS-CoV-2 detection. Journal of Virological Methods. 2023. 314
  • Hiroya Oki, Kazuki Kawahara, Minato Iimori, Yuka Imoto, Haruka Nishiumi, Takahiro Maruno, Susumu Uchiyama, Yuki Muroga, Akihiro Yoshida, Takuya Yoshida, et al. Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor. Science Advances. 2022. 8. 41. eabo3013
ｍore...
MISC (5)：
Patents (1)：
  • 病原性細菌の定着を阻害するペプチド及びそれを含む定着阻害剤
Books (1)：
  • Structual basis of type IVb pilus-mediated bacterial adhesion to the intestinal epithelium
    Spring-8 SACLA Research Frontiers 2019
Lectures and oral presentations  (19)：
  • コレラ菌が形成する IVb 型線毛 TCP による定着因子 TcpF の認識機構
    (第55回ビブリオシンポジウム 2023)
  • Mechanism of the Colonization Factor via Type lvb Pilus Tcp from Vibrio Cholerae
    (ASM Microbe 2023,Houston 2023)
  • 腸管系病原菌が形成するIVb 型線毛を介した定着因子の分泌機構
    (第96回日本細菌学会総会 2023)
  • Structural Analysis based on X-ray crystallography and Cryo-EM
    (National Institute of Cholera and Enteric Diseases (NICED) Seminar 2023)
  • コレラ菌が形成するIVb型線毛TCPを介した定着因子の分泌機構
    (第45回分子生物学会 2022)
ｍore...
Education (2)：
  • 2015 - 2019 Osaka University Graduate School of Pharmaceutical Sciences
  • 2009 - 2015 Osaka University School of Pharmaceutical Sciences
Professional career (1)：
  • 博士(薬学) (大阪大学)
Work history (2)：
  • 2019/04 - 現在 Osaka University Research Institute for Microbial Diseases
  • 2017/04 - 2019/03 Osaka University Graduate School of Pharmaceutical Sciences
Awards (1)：
  • 2019/04 - 日本細菌学会 優秀発表賞
Association Membership(s) (4)：
PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  JAPANESE SOCIETY FOR BACTERIOLOGY ,  THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN
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