Morita Kohtaro

Affiliation and department：

Research field (2)： Molecular biology , Laboratory animal science

Research keywords (6)： Zygote , Rat , Mouse , Experimental animals , Embryonic development , Epigenetics

Research theme for competitive and other funds (5)：

2023 - 2024 Identification of localised regions of histone modifications that regulate embryonic genome activation in rats.
2023 - 2024 Study on the mechanism of zyogtic genome activation using early rat embryos.
2021 - 2024 げっ歯類から中型動物までを対象とする高汎用性トランスジェニック作製技術の開発
2020 - 2023 Identification of the common mechanism of zygotic genome activation in humans using early rat embryos
2019 - 2020 ヒト初期胚の全能性獲得機構のモデル動物としてラットの活用を目的とした、ラット初期胚における胚性ゲノム活性化機構の解明及び正常発生に必要なエピジェネティックマーカーの探索

Papers (12)：

Keiji Mochida, Kohtaro Morita, Yoshio Sasaoka, Kento Morita, Hitoshi Endo, Ayumi Hasegawa, Masahide Asano, Atsuo Ogura. Superovulation with an anti-inhibin monoclonal antibody improves the reproductive performance of rat strains by increasing the pregnancy rate and the litter size. Scientific Reports. 2024. 14. 1
Kohtaro Morita, Arata Honda, Masahide Asano. A Simple and Efficient Method for Generating KO Rats Using In Vitro Fertilized Oocytes. Methods in Molecular Biology. 2023. 233-246
Kohtaro Morita, Yuki Hatanaka, Shunya Ihashi, Masahide Asano, Kei Miyamoto, Kazuya Matsumoto. Symmetrically dimethylated histone H3R2 promotes global transcription during minor zygotic genome activation in mouse pronuclei. Scientific Reports. 2021. 11. 1. 10146-10146
Tomomi Okuno, Wayne Yang Li, Yu Hatano, Atsushi Takasu, Yuko Sakamoto, Mari Yamamoto, Zenki Ikeda, Taiki Shindo, Matthias Plessner, Kohtaro Morita, et al. Zygotic Nuclear F-Actin Safeguards Embryonic Development. Cell reports. 2020. 31. 13. 107824-107824
Arata Honda, Ryoma Tachibana, Kazuya Hamada, Kohtaro Morita, Naoaki Mizuno, Kento Morita, Masahide Asano. Efficient derivation of knock-out and knock-in rats using embryos obtained by in vitro fertilization. Scientific Reports. 2019. 9. 1. 11571

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MISC (2)：

Lectures and oral presentations (107)：

Development of a chemically defined cryopreservation solution and freezing method for rat sperm.
(The 71st Annual Meeting of the Japanese Association for Laboratory Animal Science 2024)
Behavioral analysis of <i>Ghr</i> KO rats
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
Ghr欠損ラットの表現型解析
(第70回日本実験動物学会総会 2023)
NBRP-Ratにおける凍結保存精子からの個体復元法
(第16回ラットリソースリサーチ研究会 2023)
ラットの体外受精を利用した業務の効率化と利用者拡大
(第45回日本分子生物学会年会フォーラム 2022)

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Work history (2)：

2020/04 - 現在 Kyoto University Institute of Laboratory Animals, Graduate School of Medicine Program-Specific Research Associate (National BioResource Project for the Rat)
2018/04 - 2020/03 Kyoto University Institute of Laboratory Animals, Graduate School of Medicine Program-Specific Researcher (National BioResource Project for the Rat)

Association Membership(s) (3)：

Society for Reproduction and Development , The Molecular Biology Society of Japan , Japanese Association for Laboratory Aanimal Science

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