Rchr
J-GLOBAL ID：201901009220114565
Update date: Sep. 03, 2024
Shima Hiroki
Shima Hiroki
Research field (1)：
Molecular biology
Research theme for competitive and other funds (5)：
- 2020 - 2025 Development of anti-cancer strategy by exploiting BACH1 addiction
- 2020 - 2023 細胞内S-アデノシルメチオニン量変動適応機構の解析
- 2017 - 2020 Analysis of proteins involved in the MAT2A mRNA stability control
- 2016 - 2019 Screening of drug target proteins for diabetic nephropathy by identification of ChREBP complex from renal mesangial cells
- 2013 - 2015 Profiling of proteins associated with cell differentiation based on changes in relative abundance and post-translational modification.
Papers (66)：
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Kyoko Ochiai, Hiroki Shima, Toru Tamahara, Nao Sugie, Ryo Funayama, Keiko Nakayama, Tomohiro Kurosaki, Kazuhiko Igarashi. Accelerated plasma-cell differentiation in Bach2-deficient mouse B cells is caused by altered IRF4 functions. The EMBO journal. 2024
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Liang Liu, Mitsuyo Matsumoto, Miki Watanabe-Matsui, Tadashi Nakagawa, Yuko Nagasawa, Jingyao Pang, Bert K K Callens, Akihiko Muto, Kyoko Ochiai, Hirotaka Takekawa, et al. TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22. International journal of molecular sciences. 2024. 25. 8
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Suda A, Umaru BA, Yamamoto Y, Shima H, Saiki Y, Pan Y, Jin L, Sun J, Low YLC, Suzuki C, et al. Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth. Scientific reports. 2024
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Akira Sugawara, Hiroki Shimada, Yuri Otsubo, Takumi Kouketsu, Atsushi Yokoyama. Primary aldosteronism and obstructive sleep apnea: the strong ties between them. Hypertension research : official journal of the Japanese Society of Hypertension. 2023. 46. 7. 1712-1713
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Chie Suzuki, Tohru Fujiwara, Hiroki Shima, Koya Ono, Kei Saito, Hiroki Kato, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, et al. Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis. Molecular and cellular biology. 2022. 42. 12. e0014322
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MISC (9)：
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横山敦, 纐纈拓海, 尾坪優李, 沢津橋俊, 島弘季, 佐藤郁郎, 川村貞文, 鈴木貴, 五十嵐和彦, 菅原明. 核内受容体新規転写共役因子の探索. 日本アンドロロジー学会総会記事. 2022. 41st
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横山敦, 纐纈拓海, 尾坪優李, 沢津橋俊, 島弘季, 佐藤郁郎, 川村貞文, 鈴木貴, 五十嵐和彦, 菅原明. アンドロゲン受容体新規転写共役因子の探索. 日本アンドロロジー学会総会記事. 2022. 41st
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Karthigeyan Dhanasekaran, Sujata Kumari, Ramachandran Boopathi, Hiroki Shima, Amrutha Swaminathan, Mahesh Bachu, Udaykumar Ranga, Kazuhiko Igarashi, Tapas K. Kundu. Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes. FEBS JOURNAL. 2016. 283. 6. 968-985
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島弘季, 安藤亮, 玉原亨, 五十嵐和彦. ビッグデータから読み解く生命現象 単一タンパク質の徹底的リン酸化解析と機能特定:転写因子Bach2を例に. 生化学. 2016. 88. 1. 31-35-35
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李ショウ, 白木琢磨, 島弘季, 五十嵐和彦. Bach1の細胞分裂期におけるヒアルロン酸受容体と共役して分裂軸を制御するメカニズムの解明. 日本分子生物学会年会プログラム・要旨集(Web). 2013. 36th
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Professional career (1)：
- PhD (Hiroshima University)
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