Rchr
J-GLOBAL ID：201901010072437137
Update date: May. 28, 2024
Tsuchiya Takaho
ツチヤ タカホ | Tsuchiya Takaho
Affiliation and department：
Job title：
Assistant Professor
Research field (2)：
Biological, health, and medical informatics
, Systems genomics
Research keywords (7)：
情報生命科学
, Systems Biology
, Bioinformatics
, スパースモデリング
, Spatial transcriptome
, Epigenome
, Multi-omics
Research theme for competitive and other funds (5)：
- 2020 - 2023 1細胞空間トランスクリプトームによる細胞内と細胞間の統合ネットワーク推定手法開発
- 2020 - 2022 2型糖尿病の代謝アダプテーション
- 2019 - 2021 集団ゲノムデータに基づき変異を避けることによる遺伝子治療用gRNA設計法の確立
- 2019 - 2020 集団ゲノムデータに基づき変異を避けることによる遺伝子治療用gRNA設計手法の確立
- 2014 - 2017 シグナル伝達の時間パターンから解明するリガンド選択的な遺伝子発現機構
Papers (16)：
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Ruochong Wang, Futaba Kato, Rio Yasui Watson, Aaron M Beedle, Jarrod A Call, Yugo Tsunoda, Takeshi Noda, Takaho Tsuchiya, Makoto Kashima, Ayuna Hattori, et al. The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation. Life Science Alliance. 2024. 7. 5. e202302016-e202302016
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Hideki Maehara, Toshiya Kokaji, Atsushi Hatano, Yutaka Suzuki, Masaki Matsumoto, Keiichi I. Nakayama, Riku Egami, Takaho Tsuchiya, Haruka Ozaki, Keigo Morita, et al. DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle. Scientific Reports. 2023. 13. 1
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Saeko Tahara, Takaho Tsuchiya, Hirotaka Matsumoto, Haruka Ozaki. Transcription factor-binding k-mer analysis clarifies the cell type dependency of binding specificities and cis-regulatory SNPs in humans. BMC genomics. 2023. 24. 1. 597-597
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Takaho Tsuchiya, Hiroki Hori, Haruka Ozaki. CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells. Bioinformatics. 2022. 38. 21. 4868-4877
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Toshiya Kokaji, Miki Eto, Atsushi Hatano, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno, Masashi Fujii, Ken-ichi Hironaka, Yuki Ito, Riku Egami, et al. In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states. Scientific Reports. 2022. 12. 1
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MISC (8)：
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Saeko Tahara, Takaho Tsuchiya, Hirotaka Matsumoto, Haruka Ozaki. MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans. bioRxiv. 2022
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土屋貴穂. Gene therapy based on genome editing technology and population genomics. BIO Clinica. 2021. Vol.36. 5. 448-452
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Takaho Tsuchiya. Perspective of gene therapy based on genome editing technology and population genomics. Precision Medicine. 2021. Vol.4. 2. 167-171
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Takaho Tsuchiya. Genome editing technology and population genomics for gene therapy. Medical Science Digest. 2020. Vol.46. 12. 766-770
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Takaho Tsuchiya. Perspective of gene therapy and precision medicine based on population genomics. Precision Medicine. 2020. Vol.3. 10. 630-634
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Lectures and oral presentations (21)：
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Predicting SNPs' effects on transcriptional factor binding and cell-type specificity using a crowd of ChIP-seq data
(日本人類遺伝学会第67回大会)
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MOCCS-DB: ヒト転写因子認識配列の多様性データベース
(トーゴーの日シンポジウム2022)
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MOCCS-DB: ヒト転写因子認識配列の多様性データベース
(トーゴーの日シンポジウム)
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MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans
(2022年日本バイオインフォマティクス学会年会・第11回生命医薬情報学連合大会(IIBMP2022))
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MOCCSプロファイルで明らかにする、転写因子認識配列の細胞型特異性とヒト一塩基多型が 転写因子結合へ与える影響
(2022年日本バイオインフォマティクス学会年会・第11回生命医薬情報学連合大会(IIBMP2022))
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Education (3)：
- 2014 - 2017 University of Tokyo Faculty of Science Department of Biological Sciences
- 2012 - 2014 University of Tokyo Faculty of Science Department of Biophysics & Biochemistry
- 2007 - 2012 Kyoto University Faculty of Science
Professional career (1)：
- Ph.D. (The University of Tokyo)
Work history (4)：
- 2019/05 - 現在 University of Tsukuba Center for Artificial Intelligence Research
- 2019/05 - 現在 University of Tsukuba Department of Bioinformatics, Faculty Assistant Professor
- 2017/04 - 2019/03 Astellas Pharma Inc. Associate
- 2014/04 - 2017/03 Japan Society for the Promotion of Science Research Fellow (DC1)
Awards (3)：
- 2021/09 - 第10回 生命医薬情報学連合大会(IIBMP2021)Poster Award
- 2020/09 - 第9回 生命医薬情報学連合大会(IIBMP2020)Poster Award
- 2014/09 - 15th International Conference on Systems Biology Student Bursary Award
Association Membership(s) (2)：
JAPANESE SOCIETY FOR BIOINFORMATICS
, Japanese Society for Quantitative Biology
