Hirai Shinichiro

ヒライシンイチロウ | Hirai Shinichiro

Affiliation and department：
Job title： Chief

Research field (1)： Hygiene and public health (laboratory)

Research keywords (3)： Foodborne infectious disease , Molecular epidemiology , Bacterial Infection

Research theme for competitive and other funds (6)：

2024 - 2027 Elucidating the pathogenicity of Stx2f non-producing E. albertii using phylogenetic classification, and assessing its epidemiological situation
2023 - 2026 Research on accelerating food poisoning investigations to detect wide-area food poisoning outbreaks early, and establishment of investigations based on genome analysis
2020 - 2024 Study on establishing identification methods for E. albertii using phylogenetic classification and elucidating infection routes
2020 - 2023 Research on accelerating and refining food poisoning investigations for the early detection of wide-area food poisoning outbreaks
2016 - 2017 Clarification of the distribution of highly pathogenic strains of enterohemorrhagic Escherichia coli O157 in various regions of Japan

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Papers (32)：

Hachisu Y, Tamura K, Murakami K, Fujita J, Watanabe H, Tanabe Y, Kuronuma K, Kubota T, Oshima K, Maruyama T, et al. Invasive Haemophilus influenzae disease among adults in Japan during 2014-2018. Infection. 2023. 51. 2. 355-364
Hirai S*, Yokoyama E, Ando N, Seto J, Hazama K, Enomoto K, Izumiya H, Akeda Y, Ohnishi M. Another advantage of multi-locus variable-number tandem repeat analysis that can putatively subdivide enterohemorrhagic Escherichia coli O157 strains into clades by maximum a posteriori estimation. PLOS ONE. 2023. 18. 3. e0283684
Shirai T, Akagawa M, Makino M, Ishii M, Arai A, Nagasawa N, Sada M, Kimura R, Okayama K, Ishioka I, et al. Molecular evolutionary analyses of the Pseudomonas-derived cephalosporinase gene. Microorganisms. 2023. 11. 3. 635
Miyata T, Taniguchi I, Nakamura K, Gotoh Y, Yoshimura D, Itoh T, Hirai S, Yokoyama E, Ohnishi M, Iyoda S, et al. Alteration of a Shiga toxin-encoding phage associated with a change in toxin production level and disease severity in Escherichia coli. Microbial Genomics. 2023. 9. 2. mgen000935
Hirai S*, YokoyamaE, Shiwa Y, Ishige T, Ando N, Shimizu T, Murakami S. Clarification of relationship between single-nucleotide polymorphism panels of Shiga toxin-producing Escherichia coli O157:H7/H- strains. The Journal of Veterinary Medical Science. 2022. 84. 10. 1399-1405

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MISC (5)：

Kikuchi T, Hirai S, Yokoyama E. Improvement of screening of food poisoning bacteria using multiplex real-time PCR. Annual Report on Chiba Prefectural Institute of Public Health. 2018. 65. 55-61
Hirai S, Yokoyama E, Wakui T, Konishi N, Obata H, Akase S, Harada S, Kobayashi K, Mori K, Monma C, et al. Food-borne outbreak due to consumption of enterohaemorrhagic Escherichia coli O157-contaminated yukari-seasoned cucumber in Chiba and Tokyo Prefectures. Infectious Agents Surveillance Report. 2017. 38. 5. 92-94
Ikeda K, Ohbayashi H, Yamashita Y, Shiota M, Miyoshi Y, Mihira H, Mori M, Tsurumi T, Kikuchi T, Yokoyama E, et al. A case of infant botulism with acute respiratory failure and flaccid paralysis due to Clostridium butyricum infection. Infectious Agents Surveillance Report. 2016. 37. 3. 55-56
Hirai S, Matsuda T, Wakui T, Kobayashi Y, Hasegawa H, Yasuda M, Shin R. Enterohaemorrhagic Escherichia coli O157 outbreak associated with a soba restaurant. Infectious Agents Surveillance Report. 2015. 36. 5. 77-78
Kojima Y, Hirai Y, Matsuba T, Ishii K, Hirai S, Yokoyama E, Tomita A, Obata H, Kawamura M, Takahashi M, et al. Multiple infection cases by enterohaemorrhagic Escherichia coli among participants in a Beijing sightseeing Tour. Infectious Agents Surveillance Report. 2013. 34. 5. 137-139

Books (4)：

The 50-year history of Daido Life Welfare Foundation
Daido Life Welfare Foundation 2024
Modern Media
Eiken Chemical Co., Ltd. 2020
Handbook of MLVA for Enterohemorrhagic Escherichia coli (O157, O26, O111), 1st Edition
National Council of Local Public Health Laboratories 2017
Manual for the Detection of Pathogen
National Institute of Infectious Diseases 2017

Lectures and oral presentations (4)：

Symposium: Trial and error process for submitting a research paper for the first time
(The 33rd Annual Meeting of Bacterial Research Society for Kanto-Koshin-Sei Branch, The National Council of Local Institute of Public Health 2022)
Symposium: Relationship between phylogenetic groups and pathogenicity in enterohemorrhagic Escherichia coli
(The 101th Annual Meeting of Japanese Society for Bacteriology Kanto Brach 2018)
Workshop: Early determination of enterohemorrhagic Escherichia coli O157 outbreaks using MLVA"
(The 89th Annual Meeting of the Japanese Society for Bacteriology 2016)
Symposium: Influence of regulations on eating raw beef on the occurrence of enterohemorrhagic Escherichia coli infection
(The 25th Annual meeting of the Japanese veterinary Medical association (Held in Chiba) 2014)

Education (4)：

2012 - 2015 Chiba University Graduate School of Pharmaceutical Sciences Doctor Course
2007 - 2007 University of Shizuoka Graduate School of Pharmaceutical Sciences Doctor Course
2005 - 2007 University of Shizuoka Graduate School of Pharmaceutical Sciences Master Course
2001 - 2005 Niigata University of Pharmacy and Applied Life Sciences Faculty of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences

Professional career (1)：

Pharmaceutical Science (Chiba University)

Work history (6)：

2023/07 - 現在 National Institute of Infectious Diseases Center for Emergency Preparedness and Response
2020/04 - 2023/06 National Institute of Infectious Diseases Center for Emergency Preparedness and Response
2019/04 - 2020/03 National Institute of Infectious Diseases Center for Surveillance, Immunization, and Epidemiologic Research
2018/04 - 2019/03 Chiba Prefectural Isumi Public Health Center
2011/04 - 2018/03 Chiba Prefectural Institute of Public Health Division of Bacteriology

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Association Membership(s) (4)：

Japanese Society for Infection Prevention and Contro , The Japanese Association for Infectious Diseases , Japanese Society of Food Microbiology , Japanese Society for Bacteriology

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