Rchr
J-GLOBAL ID：201901010462583487
Update date: Mar. 06, 2024
Leonardo Puppulin
Leonardo Puppulin
Affiliation and department：
Research field (4)：
Nanomaterials
, Biophysics
, Biomaterials
, Biomedical engineering
Research theme for competitive and other funds (3)：
- 2019 - 2022 Nanometer scale resolution imaging of pH and reactive oxygen species on the outer membrane surface for fast and effective cell discrimination in cancer tissues.
- 2016 - 2019 Development of new methods for measuring ion concentrations in interstitial fluid using optical spectroscopy
- 2011 - 2012 人工関節用の生体材料における顕微ラマン光分析の開発
Papers (44)：
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Shotaro Tsujioka, Ayumi Sumino, Yutaro Nagasawa, Takashi Sumikama, Holger Flechsig, Leonardo Puppulin, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, et al. Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy. Science advances. 2023. 9. 26. eadh1069
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Leonardo Puppulin, Junichiro Ishikawa, Ayumi Sumino, Arin Marchesi, Holger Flechsig, Kenichi Umeda, Noriyuki Kodera, Hiroshi Nishimasu, Mikihiro Shibata. Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy. ACS Nano. 2023
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Shin Morioka, Shoko Sato, Naoki Horikoshi, Tomoya Kujirai, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, Leonardo Puppulin, Ayumi Sumino, et al. High-Speed Atomic Force Microscopy Reveals Spontaneous Nucleosome Sliding of H2A.Z at the Subsecond Time Scale. Nano letters. 2023. 23. 5. 1696-1704
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Ayumi Sumino, Yimeng Zhao, Daichi Mukai, Takashi Sumikama, Leonardo Puppulin, Motoyuki Hattori, Mikihiro Shibata. Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel. 2023
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Shotaro Tsujioka, Ayumi Sumino, Yutaro Nagasawa, Takashi Sumikama, Holger Flechsig, Leonardo Puppulin, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, et al. Evolutionarily acquired activity-dependent transformation of the CaMKII holoenzyme. 2023
ｍore...
MISC (2)：
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Ayumi Sumino, Takashi Sumikama, Leonardo Puppulin, Mikihiro Shibata, Katsumasa Irie. Dissociation and inter-channel dimerization of voltage-sensor domains (VSD) of voltage-gated Na+ channel in the resting state. The Journal of Physiological Sciences. 2023. 73. 95
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KAWAGOE Yusuke, IBA Daisuke, NAKAMURA Morimasa, PUPPULIN Leonardo, PEZZOTTI Giuseppe, MORIWAKI Ichiro. S111023 Development of Compact Bending Fatigue Test Rig for Plastic Gears in Raman Spectroscopic Analysis. Mechanical Engineering Congress, Japan. 2013. 2013. "S111023-1"-"S111023-5"
Lectures and oral presentations (3)：
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Exploring the potential of HS-AFM for simultaneous topography and molecular recognition imaging
(NanoLSI Open Seminar 2022)
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Surface enhanced Raman spectroscopy probe for nanometer-scale measurement of pH and hydrogen peroxides on the outer membrane of cells
(The 97th Annual Meeting of the Physiological Society of Japan 2020)
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Highly localized pH sensing on the outer membrane of cells using surface enhanced Raman spectroscopy
(FAOPS congress in conjunction with the 96th annual meeting of physiological society of Japan 2019)
Work history (4)：
- 2019/03 - 現在 Kanazawa University WPI Nano LIfe Science Institute Assistant professor
- 2013/09 - 2019/02 Kyoto Prefectural University of Medicine Postdoctoral researcher
- 2011/09 - 2013/08 Kyoto Institute of Technology JSPS Post-doc fellow
- 2006/05 - 2007/09 CNR Italian Council of National Research Institute of Science and Technology for Ceramic materials (ISTEC/CNR) Researcher
Association Membership(s) (1)：
Physiological Society of Japan
