Nishio Hidenori

ニシオヒデノリ | Nishio Hidenori

Affiliation and department：

Research field (1)： Urology

Research keywords (2)：エピゲノム , 精子形成

Research theme for competitive and other funds (22)：

2023 - 2028 1細胞RNA-sequenceを用いた停留精巣における精子幹細胞ニッチの遺伝子発現解析
2023 - 2027 Establishment of biomarkers of immature Sertoli cells involved in differentiation of spermatogenic stem cells and its applications for reproductive medicine
2023 - 2026 空間トランスクリプトーム解析による血液精巣関門の成立の解明と男性不妊治療への応用
2023 - 2026 幼若期の甲状腺ホルモンによる精子形成機序の解明と男性不妊症の新規治療への応用
2023 - 2026 Pip遺伝子を導入した培養口腔粘膜組織を用いる新規尿道下裂修復術の開発

2022 - 2025 機能的な構造を有する腎・尿路再生への選択的細胞抽出法を応用した基礎的研究

2022 - 2025 精子形成障害におけるエピゲノム因子の解明による男性不妊症に対する新規治療薬の確立

2021 - 2024 Comprehensive research on the roles of thyroid function involved in differentiation and proliferation of spermatogonial stem cells

2020 - 2024 Comprehensive analyses of time-specific mechanisms of spermatogonial stem cell development and novel strategy for reproductive medicine

2019 - 2023 腎前駆細胞の選択的抽出により機能的な構造を有する腎を再生するための基礎研究

2018 - 2023 精巣形成不全症候群における精子幹細胞の機能異常の同定と分化機構の解明

2018 - 2022 The elucidation of the mechanism of Kdm5a, the histone-modifying enzyme, aimed at epigenetic drug discovery for testicular dysfunction

2017 - 2020 Comprehensive elucidation of differentiation and maturation of Sertoli cells and application to reproductive medicine

2017 - 2020 The elucidation of the genetic pathway of hypospadias and development of a new surgical method using a gene transferred cell sheet

2016 - 2019 Gene expression analysis of human spermatogonial stem cell niche using single cell RNA-sequence

2015 - 2018 Elucidation of selective renal progenitor differentiation and renal regeneration mechanism using cell sorting system

2015 - 2018 The elucidation of the mechanism of Kdm5a, the histone demethylase, in the testicular function

2014 - 2017 Elucidation of characteristic alterations of spermatogonial stem cells in testicular cancer and application to genome-based drug discovery using novel cell line

2013 - 2016 Elucidation of the epigenetic regulatory network during cell differentiation of spermatogonial stem cells

2013 - 2016 The development of newly daiagnotic tool and treatment for male infertility in terms of spermatogonial stem cell activity

2012 - 2015 Elucidation of epigenetic transcriptional regulation in germ cell differentiation

2010 - 2014 Feasibility of abnormal development of spermatogonial stem cells in impaired spermatogenesis; detection of disease genes and functional analyses

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Papers (174)：

Hidenori Nishio, Kentaro Mizuno, Daisuke Matsumoto, Hideyuki Kamisawa, Satoshi Kurokawa, Akihiro Nakane, Shoichiro Iwatsuki, Tetsuji Maruyama, Takahiro Yasui, Yutaro Hayashi. Evaluation of the scrotal thermal environment and the testicular sizes in prepubertal hemiscrotal agenesis without cryptorchidism. IJU case reports. 2024. 7. 5. 404-407
Hidenori Nishio, Kentaro Mizuno, Daisuke Matsumoto, Keiichi Tozawa, Takahiro Yasui, Yutaro Hayashi. Combination of robot-assisted laparoscopic pyeloplasty for lower moiety ureteropelvic junction obstruction in a partial duplex system and percutaneous endoscopic surgery for renal calculi reusing the port for robotic pyeloplasty. IJU case reports. 2023. 6. 6. 390-393
Hidenori Nishio. Response to Comment: Surgical management of prepubertal testicular tumors: A 30-year study in our institution. International journal of urology : official journal of the Japanese Urological Association. 2023. 30. 8. 689-689
Hidenori Nishio, Kentaro Mizuno, Taiki Kato, Hideyuki Kamisawa, Satoshi Kurokawa, Akihiro Nakane, Tetsuji Maruyama, Noriyasu Kawai, Takahiro Yasui, Yutaro Hayashi. Surgical management of prepubertal testicular tumors: A 30-year study in our institution. International journal of urology : official journal of the Japanese Urological Association. 2023. 30. 6. 521-525
Hidenori Nishio, Kentaro Mizuno, Daisuke Matsumoto, Takahiro Yasui, Yutaro Hayashi. Ureterocele prolapse eliciting unusual patient behavior to control intermittent voiding. Urology case reports. 2023. 46. 102295-102295

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MISC (87)：

加藤大貴, 水野健太郎, 西尾英紀, 安井孝周, 林祐太郎. 思春期停留精巣モデルラットにおける血液精巣関門構成タンパクClaudin11の局在と精細胞の分化との関連. 日本小児泌尿器科学会雑誌. 2019. 28. 2. 149-149
加藤大貴, 濱本周造, 岡田淳志, 安井孝周, 水野健太郎, 西尾英紀, 林祐太郎. 急性胃腸炎罹患後に尿管結石嵌頓による腎後性腎不全を発症した幼児の1例. 泌尿器科紀要. 2019. 65. 6. 233-233
水野健太郎, 西尾英紀, 林祐太郎, 加藤大貴, 黒川覚史, 戸澤啓一, 安井孝周. 腹腔鏡・ロボット支援腎盂形成術:エキスパートの技術ロボット支援腎盂形成術のポイントと注意点. 日本泌尿器科学会総会. 2019. 107回. EP10-3
西尾英紀, 水野健太郎, 林祐太郎, 加藤大貴, 中根明宏, 丸山哲史, 戸澤啓一, 安井孝周. 小児泌尿器科医療における腹腔鏡手術・ロボット手術膀胱尿管逆流に対するロボット支援逆流防止術. 日本泌尿器科学会総会. 2019. 107回. SY30-3
加藤大貴, 水野健太郎, 西尾英紀, 中根明宏, 丸山哲史, 安井孝周, 林祐太郎. 思春期の停留精巣モデルラットにおける血液精巣関門関連タンパクの発現解析. 日本泌尿器科学会総会. 2019. 107回. AOP-076

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