2023 - 2026 Exploring Novel Anti-Aging and Rejuvenation Mechanisms Through Human Aging Models
2022 - 2025 Unveiling the risk factors of ageing to promote healthy longevity
2022 - 2024 Deciphering the pathogenesis of Werner syndrome using a non-human primate model and patient-specific iPS cells
2022 - 2024 Development of Innovative Treatment for Werner Syndrome
2022 - 2024 Elucidation of the relationship between aberrant nucleic acid metabolism and accelerated aging in Werner syndrome
2021 - 2024 Nationwide study to improve the quality of medical care and patient QOL through the accumulation of evidence on progeroid syndromes
2020 - 2023 Elucidating the Role of Pericyte Aging in Vascular Complications of Diabetes Mellitus
2021 - 2022 Effects of a newly discovered mitochondrial toxin on aging and its universality as an aging biomarker
2020 - 2022 Deciphering the aging mechanism directed by exosomes in the adult progeria Werner syndrome
2019 - 2021 The effects of mechanical stress on cellular senescence in adult progeria Werner syndrome
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Papers (34):
He-Ling Wang, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, et al. Meeting summary of The NYO3 5th NO-Age/AD meeting and the 1st Norway-UK joint meeting on ageing and dementia: recent progress on the mechanisms and interventional strategies. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024
Hiyori Kaneko, Yoshiro Maezawa, Ayano Tsukagoshi-Yamaguchi, Masaya Koshizaka, Aki Takada-Watanabe, Rito Nakamura, Shinichiro Funayama, Kazuto Aono, Naoya Teramoto, Daisuke Sawada, et al. Sex differences in symptom presentation and their impact on diagnostic accuracy in Werner syndrome. Geriatrics & gerontology international. 2023
Daisuke Sawada, Hisaya Kato, Hiyori Kaneko, Daisuke Kinoshita, Shinichiro Funayama, Takuya Minamizuka, Atsushi Takasaki, Katsushi Igarashi, Masaya Koshizaka, Aki Takada-Watanabe, et al. Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome. Aging. 2023. 15
Clinical and Basic Biology of Werner Syndrome, the Model Disease of Human Aging. In: Mori, N. (eds) Aging Mechanisms II .
Springer, Singapore. 2022 ISBN:9789811679766
2015 - 2019 Chiba University Graduate School of Medical and Pharmaceutical Sciences, Ph.D. Program Graduate student
2015 - 2016 Hiroshima University Graduate School of Biomedical and Health Sciences Department of Cellular and Molecular Biology Visiting graduate student
2005 - 2011 Chiba University School of Medicine Undergraduate student
Professional career (2):
Ph.D. (Chiba University Graduate School of Medical and Pharmaceutical Sciences)
M.D. (Chiba University School of Medicine)
Work history (3):
2020/06 - 現在 Chiba University Department of Endocrinology, Hematology and Gerontology, Graduate School of Medicine Assistant Professor
2019/04 - 2020/05 Chiba University Department of Endocrinology, Hematology and Gerontology, Graduate School of Medicine Assistant Professor
2015/04 - 2019/03 Chiba University Department of Endocrinology, Hematology and Gerontology, Graduate School of Medicine Clinical Fellow
Committee career (1):
2023/06 - 現在 The Japan Geriatrics Society Delegate
Awards (2):
2022/06 - The Japan Geriatrics Society 4th Young Investigator Award, The Japan Geriatrics Society
2018/02 - The RECQ Organizing Committee & Japan Intractable Diseases (Nanbyo) Research Foundation Poster Award
Association Membership(s) (4):
The Japan Endocrine Society
, The Japan Geriatrics Society
, The Japan Diabetes Society
, The Japanese Society of Internal Medicine