Rchr
J-GLOBAL ID:201901010975824218   Update date: Feb. 13, 2025

KATO Hisaya

カトウ ヒサヤ | KATO Hisaya
Affiliation and department:
Job title: Assistant Professor
Research field  (1): Internal medicine - General
Research keywords  (7): CRISPR ,  Genome editing ,  Mesenchymal stem cell ,  Progeroid syndrome ,  iPS cells ,  Werner syndrome ,  Aging
Research theme for competitive and other funds  (15):
  • 2024 - 2028 Accelerating Aging Effects of Mitochondrial Metabolic Abnormalities in Human Aging Models
  • 2024 - 2027 Multidisciplinary research aiming at improving the medical standards and better prognosis of progeroid syndromes
  • 2024 - 2027 Development of Innovative Treatment for Werner Syndrome
  • 2023 - 2026 Evidence creation and treatment development by accumulating long-term data based on the Werner Syndrome Registry
  • 2023 - 2026 Multifaceted Analysis of Progeroid Syndromes for Understanding the Pathophysiology of Aging and Diseases
Show all
Papers (47):
  • Kazuto Aono, Masaya Koshizaka, Mayumi Shoji, Hiyori Kaneko, Yukari Maeda, Hisaya Kato, Yoshiro Maezawa, Makoto Miyabayashi, Mai Ishikawa, Akiko Sekiguchi, et al. Less frequent skin ulcers among patients with Werner syndrome treated with pioglitazone: findings from the Japanese Werner Syndrome Registry. Aging. 2024. 16
  • Kazuto Aono, Yoshiro Maezawa, Hisaya Kato, Hiyori Kaneko, Yoshitaka Kubota, Toshibumi Taniguchi, Toshiyuki Oshitari, Sei-Ichiro Motegi, Hironori Nakagami, Akira Taniguchi, et al. Recommendations for cancer screening and surveillance in patients with Werner syndrome. Geriatrics & Gerontology International. 2024
  • Sudip Kumar Paul, Motohiko Oshima, Ashwini Patil, Masamitsu Sone, Hisaya Kato, Yoshiro Maezawa, Hiyori Kaneko, Masaki Fukuyo, Bahityar Rahmutulla, Yasuo Ouchi, et al. Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model. Nature communications. 2024. 15. 1. 4772-4772
  • 寺本 直弥, 前澤 善朗, 山口 彩乃, 金子 ひより, 南塚 拓也, 加藤 尚也, 井出 真太郎, 井出 佳奈, 北本 匠, 越坂 理也, et al. 腎糸球体ポドサイトの転写因子Tcf21は糖尿病状態においてポドサイトと内皮細胞のクロストークに関与し、糖尿病関連腎臓病に保護的となる. 日本内分泌学会雑誌. 2024. 100. 1. 317-317
  • 金子 ひより, 加藤 尚也, 船山 真一郎, 青野 和人, 宮林 諒, 佐藤 哲太, 山口 彩乃, 寺本 直弥, 南塚 拓也, 前田 祐香里, et al. 早老症ウェルナー症候群iPS細胞由来骨格筋細胞を用いたサルコペニア発症機序の解明. 糖尿病. 2024. 67. Suppl.1. S-217
more...
MISC (31):
  • 加藤 尚也, 船山 真一郎, 前澤 善朗, 横手 幸太郎. 【細胞老化-真の機能を深く理解する 疾患予防・治療に向けてセノリティクスの本質的な課題に挑む】(第6章)モデル動物・疾患と細胞老化 早老症を介した抗老化・若返り研究 老化モデルがジェロサイエンスの未来を切り拓く. 実験医学. 2024. 42. 20. 3267-3272
  • 北川柚香, 雨宮歩, 田原裕希恵, 緒方英之, 加藤尚也, 秋田新介, 前澤善朗, 越坂理也, 越坂理也, 三川信之. 遺伝性早老症ウェルナー症候群の下肢可動域制限と潰瘍形成の実態:横断観察研究. 日本フットケア・足病医学会年次学術集会プログラム・抄録集. 2023. 4th
  • 前澤 善朗, 寺本 直弥, 塚越 彩乃, 南塚 拓也, 加藤 尚也, 金子 ひより, 越坂 理也, 遠藤 裕介, 秋元 義弘, 横手 幸太郎. 糖尿病性腎臓病のポドサイトにおける転写因子Tcf21の役割. 糖尿病. 2022. 65. Suppl.1. S-149
  • 塚越 彩乃, 前澤 善朗, 遠藤 裕介, 寺本 直弥, 金子 ひより, 南塚 拓也, 加藤 尚也, 越坂 理也, 横手 幸太郎. 糖尿病性腎臓病の間質線維化における加齢、細胞老化の役割の解明. 糖尿病. 2022. 65. Suppl.1. S-150
  • 加藤 尚也, 越坂 理也, 石川 耕, 石橋 亮一, 石川 崇広, 前澤 善朗, 横手 幸太郎. 内臓脂肪減少に関するイプラグリフロジンおよびメトホルミン著効例の解析 無作為化比較試験PRIME-Vサブ解析. 糖尿病. 2019. 62. Suppl.1. S-303
more...
Patents (2):
  • METHOD FOR EVALUATING AGING
  • ANTISENSE OLIGOMER
Books (4):
  • Clinical and Basic Biology of Werner Syndrome, the Model Disease of Human Aging. In: Mori, N. (eds) Aging Mechanisms II .
    Springer, Singapore. 2022 ISBN:9789811679766
  • 早老症にみる細胞、個体の老化と寿命の延長 生物の寿命延長 老化・長寿命の基盤研究最前線
    エヌ・ティー・エス 2022 ISBN:9784860437732
  • 小象の元気!で行こう : 子ども達から高齢者まで身体の不思議を知って生活習慣病を防ぐ70話
    生活習慣病防止に取り組む市民と医療者の会 2021
  • 高齢者糖尿病 診療ガイドライン 2017
    南江堂 2017 ISBN:9784524252848
Lectures and oral presentations  (25):
  • A clinical trial of nicotinamide riboside for patients with Werner syndrome: EMPOWER
    (Third Meeting of the Anglo-Japanese Global Partnership Award Group 2025)
  • Aging research and therapeutic development based on the progeroid Werner syndrome
    (SPC (Science Pioneers Consortium) 2024 2024)
  • The role of GLP-1 receptor agonists in diabetes treatment
    (GLP-1 Web seminar 2024)
  • Translational Research in Werner Syndrome as a Model of Progeria: Including Implications for Diabetes Treatment
    (13th Clinical & Basic Research Forum 2024)
  • Innovative Treatments for Werner Syndrome Using NAD+ Precursors and Development of Nucleic Acid Therapeutics via Exon Skipping
    (The 66th Annual Meeting of the Japan Geriatrics Society 2024)
more...
Education (3):
  • 2015 - 2019 Chiba University Graduate School of Medical and Pharmaceutical Sciences, Ph.D. Program Graduate student
  • 2015 - 2016 Hiroshima University Department of Cellular and Molecular Biology, Graduate School of Biomedical and Health Sciences Visiting graduate student
  • 2005 - 2011 Chiba University School of Medicine Undergraduate student
Professional career (2):
  • Ph.D. (Chiba University Graduate School of Medical and Pharmaceutical Sciences)
  • M.D. (Chiba University School of Medicine)
Work history (3):
  • 2020/06 - 現在 Chiba University Department of Endocrinology, Hematology and Gerontology, Graduate School of Medicine Assistant Professor
  • 2019/04 - 2020/05 Chiba University Department of Endocrinology, Hematology and Gerontology, Graduate School of Medicine Assistant Professor
  • 2015/04 - 2019/03 Chiba University Department of Endocrinology, Hematology and Gerontology, Graduate School of Medicine Clinical Fellow
Committee career (1):
  • 2023/06 - 現在 The Japan Geriatrics Society Delegate
Awards (4):
  • 2024/12 - Science Pioneers Consortium & Taisho Pharmaceutical Co., Ltd. Young Investigator Taisho Award (YITA)
  • 2022/06 - The Japan Geriatrics Society The 4th Japan Geriatrics Society Young Investigator Award
  • 2022/01 - Japan Intractable Diseases (Nanbyo) Research Foundation FY2021 Medical Research Encouragement Grant
  • 2018/02 - The RECQ Organizing Committee & Japan Intractable Diseases (Nanbyo) Research Foundation Poster Award
Association Membership(s) (4):
The Japan Endocrine Society ,  The Japan Geriatrics Society ,  The Japan Diabetes Society ,  The Japanese Society of Internal Medicine
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