Hattori Kazuki

Affiliation and department：

Research field (4)： Pharmaceuticals - health and biochemistry , Cell biology , Molecular biology , Biomedical engineering

Research keywords (6)： intestinal organoid , マイクロ流体技術 , Cell signaling , adipocyte , MAPK , Extracellular Vesicle

Research theme for competitive and other funds (17)：

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Papers (22)：

Koki Kunitake, Tadahaya Mizuno, Kazuki Hattori, Chitose Oneyama, Mako Kamiya, Sadao Ota, Yasuteru Urano, Ryosuke Kojima. Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis and release regulators. Nature Communications. 2024
Ruri Maekawa, Kazuki Hattori, Hiromi Kirisako, Yuichiro Iwamoto, Fumiko Kawasaki, Takeshi Yoneshiro, Juro Sakai, Sadao Ota. Large-scale generation of uniform sub-100 μm adipocyte spheroids in hydrogel microcapsules using a flow-focusing microfluidic device. bioRxiv. 2024
Minato Yamashita, Miu Tamamitsu, Hiromi Kirisako, Yuki Goda, Xiaoyao Chen, Kazuki Hattori, Sadao Ota. High-throughput 3D imaging flow cytometry of suspended adherent 3D cell cultures. Small Methods. 2023
Yoshiyuki Tsuyama, Bin Xu, Kazuki Hattori, Seugho Baek, Yusuke Yoshioka, Ryosuke Kojima, Younghak Cho, Thomas Laurell, Soyoun Kim, Sadao Ota, et al. A 50 μm acoustic resonator microchannel enables focusing 100 nm polystyrene beads and sub-micron bioparticles. Sensors and Actuators B: Chemical. 2023. 376. 132918-132918
Kazuki Hattori, Yuki Goda, Minato Yamashita, Yusuke Yoshioka, Ryosuke Kojima, Sadao Ota. Droplet Array-Based Platform for Parallel Optical Analysis of Dynamic Extracellular Vesicle Secretion from Single Cells. Analytical Chemistry. 2022. 94. 32. 11209-11215

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MISC (3)：

Hattori, K, Goda, Y, Yamashita, M, Yoshioka, Y, Kojima, R, Ota, S. Droplet Array-Based Platform for Time-Lapse Quantification of Extracellular Vesicle Release from Single Cells. Proceedings of Micro Total Analysis Systems 2022. 2022
Yamashita, M, Hattori, K, Kirisako, H, Chen, X, Ugawa, M, Ota, S. High-Throughput Parallel Optofluidic 3d-Imaging of Adherent Cells in Adherent State. Proceedings of Micro Total Analysis Systems 2022. 2022
Hattori, K, Goda, Y, Yoshioka, Y, Kojima, R, Ota, S. Single-Cell Temporal Quantification Platform of Secreted Extracellular Vesicle. Proceedings of Micro Total Analysis Systems. 2021

Patents (1)：

Books (4)：

Analysis of heterogeneous cellular responses using sub-millimeter compartmentalized units
2024
液滴アレイを用いた、細胞外小胞放出ダイナミクスの大量1細胞計測
化学とマイクロ・ナノシステム学会誌, Vol. 23, No. 1 2024
細胞死 -Cell Death- その分子機構, 生理機能, 病態制御
化学同人 2019
生体の科学
医学書院 2015

Lectures and oral presentations (22)：

マイクロ液滴を用いた、1細胞分泌ダイナミクスの計測
(第15回「光塾」 2024)
三次元培養モデルの大量・並列解析による、in vivoの再現
(第46回日本分子生物学会年会 2023)
摂動から細胞応答を1細胞・多細胞・個体モデルで繋ぐ
(第96回日本生化学会大会 2023)
Organoid-based screening for modulators of the cellular composition of intestinal epithelia
(55th Annual Meeting of the Japanese Society of Developmental Biologists 2022)
Single-Cell Temporal Quantification Platform of Secreted Extracellular Vesicle
(Micro Total Analysis Systems 2021 2021)

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Education (3)：

Work history (7)：

2020/11 - 現在 The University of Tokyo Research Center for Advanced Science and Technology Research Associate (Project Assistant Professor)
2020/08 - 2020/10 The University of Tokyo Research Center for Advanced Science and Technology Project Researcher
2018/09 - 2020/06 Brigham & Women's Hospital / Harvard Medical School Division of Engineering in Medicine, Department of Medicine Research Fellow, Collaborator
2018/05 - 2020/06 Massachusetts Institute of Technology David H. Koch Institute for Integrative Cancer Research Postdoctoral Fellow, Research Affiliate
2015/04 - 2018/03 The University of Tokyo Graduate School of Pharmaceutical Sciences Research Associate (Assistant Professor)

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Awards (7)：

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Association Membership(s) (4)：

化学とマイクロ・ナノシステム学会 , 日本分子生物学会 , 日本肥満学会 , 日本生化学会

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