Research theme for competitive and other funds (5)：
2022 - 2025 Pathophysiology research of pre-eclampsia by epitranscriptome analysis using human placental stem cells
2023 - 2025 Study of an AI program medical device that predicts the onset of labor by monitoring biological information using a wearable healthcare device
2020 - 2022 TGFβ-SMADを介した胎盤m6A修飾解析による妊娠合併症の病態解明
2018 - 2020 Fuction of m6A RNA modifications in human placenta.
2014 - 2017 Identification of diet contents regulating RNA methylation and those effects on fetal growth
Papers (27)：
Ichiro Takeuchi, Kanako Tanase-Nakao, Ayame Ogawa, Tohru Sugawara, Osuke Migita, Makoto Kashima, Touko Yamazaki, Akihiro Iguchi, Yasuhiro Naiki, Toru Uchiyama, et al. Congenital anaemia associated with loss-of-function variants in DNA polymerase epsilon 1. Journal of medical genetics. 2023
Kosuke Taniguchi, Fuyuki Hasegawa, Yuka Okazaki, Asuka Hori, Hiroko Ogata-Kawata, Saki Aoto, Osuke Migita, Tomoko Kawai, Kazuhiko Nakabayashi, Kohji Okamura, et al. Re-evaluation of whole exome sequencing, including intronic region, in combination with genetic intolerance score for detecting foetal structural anomalies in X-linked disorders. 2023
Kyoko Oshina, Yoshimasa Kamei, Asuka Hori, Fuyuki Hasegawa, Kosuke Taniguchi, Ohsuke Migita, Atsuo Itakura, Kenichiro Hata. A novel FLNA variant in a fetus with skeletal dysplasia. Human genome variation. 2022. 9. 1. 45-45
Yukari Kobayashi, Yuki Ito, Kosuke Taniguchi, Kana Harada, Michihiro Yamamura, Taisuke Sato, Ken Takahashi, Hiroshi Kawame, Kenichiro Hata, Osamu Samura, et al. Novel missense COL2A1 variant in a fetus with achondrogenesis type II. Human genome variation. 2022. 9. 1. 40-40
Yuka Okazaki, Kosuke Taniguchi, Yoshitaka Miyamoto, Shiori Kinoshita, Kazuhiko Nakabayashi, Kayoko Kaneko, Hiromi Hamada, Toyomi Satoh, Atsuko Murashima, Kenichiro Hata. Glucocorticoids increase the risk of preterm premature rupture of membranes possibly by inducing ITGA8 gene expression in the amnion. Placenta. 2022. 128. 73-82
谷口 公介. ヒト胎盤におけるepitranscriptomeの特性分析 5'-untranslated regionのN6-メチルアデノシンによる修飾は胎児の成長と子癇前症に関連している(Epitranscriptomic Profiling in Human Placenta: N6-methyladenosine Modification at the 5'-untranslated Region is Related to Fetal Growth and Preeclampsia). 京都府立医科大学雑誌. 2020. 129. 6. 456-457
Epitranscriptomic profiling in human placenta
(Human Genetics Asia 2023)
A new genetic diagnostic method including introns for undiagnosed fetal structural anomalies by whole exome sequencing
(2022)
計画無痛分娩について考える
(日本産科麻酔科学会 2016)
Education (2)：
2014 - 2018 Graduate School of Medical Science Kyoto Prefectural University of Medicine Department of Obstetrics and Gynecology
2002 - 2008 Kyoto Prefectural University of Medicine
Professional career (1)：
PhD (Kyoto Prefectural University of Medicine)
Work history (7)：
2023/06 - 現在 National Center for Child Health and Development
2023/04 - 現在 Gunma University
2020/04 - 2023/03 National Center for Child Health and Development Maternal Fetal Biology
2018/04 - 2020/03 National Research Institute for Child Health and Development medical genome center reseacher
2014/04 - 2018/03 National Research Institute for Child Health and Development Department of Maternal-Fetal Biology
2011/04 - 2014/03 National Research Institute for Child Health and Development Center of Maternal-Fetal, Neonatal and Reproductive Medicine.
2010/04 - 2011/03 Kyoto Prefectural University of Medicine Department of Obstetrics and Gynecology,
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Awards (1)：
2017/08 - International Federation of Placental Association Elsevier New Investigator Travel Awards The placental epitranscriptome: post-transcriptional m6A modification at 5' UTR may relate fetal growth
Association Membership(s) (3)：
JAPAN SOCIETY OF PERINATAL AND NEONATAL MEDICINE
, THE JAPAN SOCIETY OF HUMAN GENETICS
, JAPAN SOCIETY OF OBSTETRICS AND GYNECOLOGY
