Harayama Takeshi

Affiliation and department：

Research field (2)： Cell biology , Molecular biology

Research keywords (5)： Genetics , Genome editing , Enzymology , Mass spectrometry , Lipids

Research theme for competitive and other funds (2)：

2014 - 2017 Analysis of biological function regulated by membrane phospholipid diversity
2012 - 2017 Biology of diversity and asymmetry of membrane lipids

Papers (28)：

Fumie Hamano, Kazuaki Matoba, Tomomi Hashidate-Yoshida, Tomoyuki Suzuki, Kiyotake Miura, Daisuke Hishikawa, Takeshi Harayama, Koichi Yuki, Yoshihiro Kita, Nobuo N. Noda, et al. Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA. The FASEB Journal. 2021. 35. 6
J. Thomas Hannich, Ursula Loizides-Mangold, Flore Sinturel, Takeshi Harayama, Bart Vandereycken, Camille Saini, Pauline Gosselin, Marie-Claude Brulhart-Meynet, Maud Robert, Stephanie Chanon, et al. Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients. Acta Physiologica. 2021
Takeshi Harayama, Takao Shimizu. Roles of polyunsaturated fatty acids, from mediators to membranes. Journal of Lipid Research. 2020. 61. 8. 1150-1160
Morstein J, Hill RZ, Novak AJE, Feng S, Norman DD, Donthamsetti PC, Frank JA, Harayama T, Williams BM, Parrill AL, et al. Optical control of sphingosine-1-phosphate formation and function. Nature chemical biology. 2019
Feng S, Harayama T, Chang D, Hannich JT, Winssinger N, Riezman H. Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures. Chemical science. 2019. 10. 8. 2253-2258

ｍore...

MISC (3)：

Noemi Jiménez-Rojo, Suihan Feng, Johannes Morstein, Stefanie D. Pritzl, Takeshi Harayama, Antonino Asaro, Nynke A. Vepřek, Christopher J. Arp, Martin Reynders, Alexander J. E. Novak, et al. Optical Control of Membrane Fluidity Modulates Protein Secretion. 2022
Establishment of a highly efficient gene disruption strategy to analyze and manipulate lipid co-regulatory networks. 2020
Takeshi Harayama. Membrane Biology: Transmembrane Helices Need to Fit the Surrounding Fat. CURRENT BIOLOGY. 2020. 30. 3. R122-R124

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