Rchr
J-GLOBAL ID：201901011306564460
Update date: Jan. 30, 2024
Nakashima Ken-ichi
ナカシマ ケンイチ | Nakashima Ken-ichi
Affiliation and department：
Homepage URL (1)：
http://www.phar.agu.ac.jp/lab/med_res/top.html
Research field (2)：
Environmental and pharmaceutical development resources
, Pharmaceuticals - chemistry and drug development
Research keywords (5)：
生薬学
, 天然物化学
, 植物内生真菌
, ケミカルバイオロジー
, 核内受容体
Research theme for competitive and other funds (5)：
- 2021 - 2025 mRNAシーケンスを用いたエンドファイト由来機能性物質の効率的な探索
- 2019 - 2022 Development of natural products based on regulation of biological clock system
- 2018 - 2021 Elucidation of the ecology of plant endophytic fungi by natural product chemistry and approaches to their utilization as useful resources
- 2014 - 2017 Application of naturally occurring retinoid X receptor agonists to lifestyle-related diseases and inflammatory diseases
- 2011 - 2013 Metagenomic approach to identify agents to restore anti-pseudomonas drugs against multidrug resistant Pseudomonas aeruginosa (MDRP): use of MDRP mutants lacking multidrug efflux pumps.
Papers (40)：
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Ken-ichi Nakashima, Marina Okamura, Imari Matsumoto, Nanae Kameda, Tomoe Tsuboi, Eiji Yamaguchi, Akichika Itoh, Makoto Inoue. Regulation of adipogenesis through retinoid X receptor and/or peroxisome proliferator-activated receptor by designed lignans based on natural products in 3T3-L1 cells. Journal of Natural Medicines. 2023. 77. 2. 315-326
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Ken-ichi Nakashima, Yuka Higuchi, Junko Tomida, Yoshiaki Kawamura, Makoto Inoue. Two new ɑ-pyrone derivatives from the endophytic Diaporthe sp. ECN371. Journal of Natural Medicines. 2022. 76. 2. 462-467
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Genki Kiyama, Ken-ichi Nakashima, Kazumasa Shimada, Naoko Murono, Wataru Kakihana, Hideki Imai, Makoto Inoue, Takao Hirai. Transmembrane G protein-coupled receptor 5 signaling stimulates fibroblast growth factor 21 expression concomitant with up-regulation of the transcription factor nuclear receptor Nr4a1. Biomedicine & Pharmacotherapy. 2021. 142. 112078-112078
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Ken-ichi Nakashima, Junko Tomida, Yoshiaki Kawamura, Makoto Inoue. A New Chromone Derivative from Endophytic Fungus Xylaria sp. ECN212. HETEROCYCLES. 2021. 102. 5. 955-955
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Ken-ichi Nakashima, Junko Tomida, Tomoe Tsuboi, Yoshiaki Kawamura, Makoto Inoue. Muyocopronones A and B: azaphilones from the endophytic fungus Muyocopron laterale. Beilstein Journal of Organic Chemistry. 2020. 16. 2100-2107
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Patents (2)：
Professional career (1)：
Work history (3)：
- 2020/10 - 現在 Aichi Gakuin University School of Pharmacy
- 2017/04 - 2020/09 Aichi Gakuin University School of Pharmacy
- 2012/04 - 2017/03 Aichi Gakuin University School of Pharmacy
Awards (2)：
- 2022/09 - 日本生薬学会 学術奨励賞
- 2020/02 - 日本生薬学会 JNM論文賞
Association Membership(s) (2)：
THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF PHARMACOGNOSY
