Rchr
J-GLOBAL ID：201901011358975817   Update date: Jan. 30, 2024

Ichinose Akitada

Ichinose Akitada
Affiliation and department：
山形大学医学部

About 山形大学医学部


Job title： 客員教授
Research field  (1)： Hematology and oncology
Research theme for competitive and other funds  (9)：
  • 2016 - 2019 Molecular pathology of autoimmune hemorrhaphilia XIII/13; analysis of anti-factor XIII autoantibodies and elucidation of the mechanism of their generation
  • 2015 - 2018 Molecular mechanism elucidation of alternative fibrin degradation pathway aiming for diagnosis and treatment of plasminogen deficiency
  • 2013 - 2016 The Pathogenesis of Autoimmune Hemorrhaphilia XIII/13: Analysis of Anti-FXIII/13 Autoantibodies and Elucidation of Their Generation Mechanisms
  • 2010 - 2012 Novel functions and Mechanisms of Coagulation Factor XIII/13 in the Platelet/Fibrin Clot Retraction Reaction
  • 2003 - 2006 Analyses on Mechanisms for Biosynthesis and Release of Human Coagulation Factor XIII at Molecular, Cellular, and Individual Levels.
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Papers (102)：
  • Tsukasa Osaki, Masayoshi Souri, Chikako Yokoyama, Yasuo Magari, Akitada Ichinose. Unmet Need for Reliable Immunological Detection Method for Anti-von Willebrand Factor Autoantibodies. Thrombosis and haemostasis. 2023. 123. 4. 478-481
  • Tsukasa Osaki, Chikako Yokoyama, Yasuo Magari, Masayoshi Souri, Akitada Ichinose. Novel immunochromatographic test for anti-factor XIII B subunit autoantibodies to diagnose autoimmune acquired factor XIII deficiency. Thrombosis and haemostasis. 2023
  • Tsukasa Osaki, Masayoshi Souri, Tatsuhiko Ozawa, Atsushi Muraguchi, Akitada Ichinose. Epitope analysis of human monoclonal antibodies from a patient with autoimmune factor XIII deficiency reveals their inhibitory mechanisms. FEBS Letters. 2023. 597. 9. 1275-1289
  • Masayoshi Souri, Chikako Yokoyama, Tsukasa Osaki, Akitada Ichinose. Antibodies against non-catalytic B subunit of factor XIII inhibit activation of factor XIII and fibrin crosslinking. Thrombosis and haemostasis. 2023
  • Masayoshi Souri, Tatsuhiko Ozawa, Tsukasa Osaki, Takatoshi Koyama, Atsushi Muraguchi, Akitada Ichinose. Cloning of human anti-factor XIII monoclonal antibody dissects mechanisms of polyclonal antibodies in a single patient. Journal of Thrombosis and Haemostasis. 2023. 21. 2. 255-268
ｍore...
MISC (5)：
  • M. Tsuda, J. Kiyasu, K. Sugio, D. Hidaka, M. Ikeda, E. Fujioka, M. Souri, T. Osaki, Y. Yufu, A. Ichinose. Spontaneous splenic rupture accompanied by hepatic arterial dissection in a patient with autoimmune haemorrhaphilia due to anti-factor XIII antibodies. Haemophilia. 2016. 22. 4. e314-e317
  • M. Souri, T. Osaki, A. Ichinose. Development of a novel assay method of coagulation factor XIII activity for the detection of its inhibitor in plasma. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015. 13. 190-190
  • Yoshiyuki Ogawa, Masahiro Mihara, Masayoshi Souri, Kunio Yanagisawa, Toshimasa Hayashi, Nobuhiko Kobayashi, Hiroaki Shimizu, Hirono Iriuchishima, Takuma Ishizaki, Hiroshi Handa, et al. Complete remission* achieved by steroid pulse therapy following rituximab treatment in a case with autoimmune haemorrhaphilia due to anti-factor XIII antibodies. Thrombosis and Haemostasis. 2014. 112. 4. 831-833
  • ICHINOSE Akitada. Factor XIII is a key molecule at the intersection of coagulation and fibrinolysis as well as inflammation and infection control. 2012. 95. 4. 362-370
  • ICHINOSE Akitada, SOURI Masayoshi. Reduced difference of α_2-plasmin inhibitor levels between plasma and serum in patients with severe factor XIII deficiency, including autoimmune hemorrhaphilia due to anti-factor XIII antibodies. 2012. 95. 1. 47-50
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