Rchr
J-GLOBAL ID：201901011476700717
Update date: Dec. 04, 2024
Hamashima Yoshitaka
ハマシマ ヨシタカ | Hamashima Yoshitaka
Affiliation and department：
Homepage URL (1)：
http://w3pharm.u-shizuoka-ken.ac.jp/lsocus/
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (17)：
- 2022 - 2025 チオカルボニル化合物の光触媒特性の解明と環境調和型分子変換法の開発
- 2021 - 2024 会合型多機能性触媒の創製と光反応の不斉制御
- 2020 - 2023 Basic study for developing NASH therapeutic drugs by using a small molecule derived from the cellular slime mold serving as a lead compound
- 2019 - 2022 Selective Fluorofunctionalization with Dianionic Catalysts
- 2016 - 2019 A novel approach to chirality control in the synthesis of organofluorine compounds
- 2014 - 2016 不斉ハロ環化反応による高機能性キラル合成素子の開発
- 2014 - 2016 Asymmetric C-H oxidation with a designed self-assembling catalyst
- 2012 - 2014 不斉ハロラクトン化反応と生物活性天然物の効率的合成
- 2011 - 2014 Synthetic study on biological active natural products by means of Ugi reaction
- 2010 - 2012 SAR studies for epigenetic research based on natural product synthesis
- 2008 - 2009 二重活性化を目指した触媒設計と分子変換反応の開発
- 2007 - 2007 基質との相互作用を引き金とする二成分活性化を目指した不斉触媒の開発研究
- 2006 - 2007 光学活性フッ素含有化合物の多面的合成研究
- 2004 - 2007 細胞の増殖と死を制御する分子の創製と機能解析
- 2004 - 2005 遷移金属エノラートの生成を鍵とする触媒的不斉フッ素化の開発と医薬化学的応用
- 2003 - 2004 Construction of focused library and the development of protein tyrosine phosphatase inhibitor
- 2002 - 2003 酸性条件下で発生させた遷移金属エノラートを鍵とする触媒的不斉反応の開発
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Papers (127)：
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Kaichi Sato, Hiromichi Egami, Yoshitaka Hamashima. Thiobenzoic Acid-Catalyzed Cα-H Cross Coupling of Benzyl Alcohols with α-Ketoacid Derivatives. Organic Letters. 2024. 26. 25. 5285-5289
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Kenji Yamashita, Fumiya Kawahara, Yoshitaka Hamashima. Benzylic C(sp3)-H Alkoxylation through Visible-Light-Driven Oxidative Radical-Polar Crossover. Asian Journal of Organic Chemistry. 2024
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Chino Igarashi, Tomoya Mayumi, Hiromichi Egami, Yoshitaka Hamashima. Asymmetric Fluorocyclization of Difluoroalkenes with Concomitant Formation of a Trifluoromethyl Group. Organic Letters. 2024. 26. 8. 1723-1727
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Makoto Inai, Hiroto Sagara, Yoshinori Ueno, Hitoshi Ouchi, Fumihiko Yoshimura, Tomohiro Asakawa, Yoshitaka Hamashima, Toshiyuki Kan. Total Synthesis of (+)-Silybin A. Chemical & pharmaceutical bulletin. 2024. 72. 6. 570-573
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Eiji Sugiyama, Yuki Nishiya, Kenji Yamashita, Ryo Hirokawa, Yoshiteru Iinuma, Takashi Nirasawa, Hajime Mizuno, Yoshitaka Hamashima, Kenichiro Todoroki. Charged chiral derivatization for enantioselective imaging of D-,L-2-hydroxyglutaric acid using ion mobility spectrometry/mass spectrometry. Chemical communications (Cambridge, England). 2023
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MISC (100)：
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廣川遼, 市川守, 久永達成, 川戸勇士, 滝田良, 滝田良, 渡邉康平, 山下賢二, 濱島義隆. Asymmetric bromocyclization reactions enabled by Lewis/Bronsted base concerted catalysis of chiral bisphosphine oxide. 日本薬学会年会要旨集(Web). 2023. 143rd
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廣川遼, 市川守, 久永達成, 川戸勇士, 滝田良, 滝田良, 渡邉康平, 山下賢二, 濱島義隆. キラルビスホスフィンオキシドのLewis/Bronsted塩基協奏触媒作用に基づく不斉ブロモ環化反応. 有機合成シンポジウム講演予稿集. 2022. 121st
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廣川遼, 市川守, 久永達成, 川戸勇士, 滝田良, 渡邉康平, 山下賢二, 濱島義隆. Parallel kinetic resolution via bromocyclization reaction based on novel catalysis of phosphine oxide. 複素環化学討論会講演要旨集. 2021. 50th
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Satoshi Hirano, Hiroyuki Koide, Takahumi Ide, Yoshitaka Hamashima, Naoto Oku, Tomohiro Asai. Design of multi-functionalized liposomes for adsorbing and neutralizing target molecules in vivo. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2019. 258
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Ayaka Masuda, Hiroyuki Koide, Hiromichi Egami, Yoshitaka Hamashima, Naoto Oku, Tomohiro Asai. Development of polymer nanoparticles adsorbing alpha-glucosidase for diabetes treatment. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2019. 258
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Professional career (1)：
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