Rchr
J-GLOBAL ID：201901011543276763   Update date: Oct. 23, 2024

Akazawa Satoru

アカザワ サトル | Akazawa Satoru
Affiliation and department：
Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University Department of Endocrinology and Metabolism, Unit of Translational Medicine

About Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University Department of Endocrinology and Metabolism, Unit of Translational Medicine


Job title： Assistant Professor
Research field  (1)： Internal medicine - General
Research keywords  (4)： Autoimmunity ,  endocrinology ,  Diabetes ,  Type 1 diabetes
Research theme for competitive and other funds  (5)：
  • 2022 - 2026 Investigation for development of a Biomarker on antigen specific T cells in type 1 diabetes
  • 2021 - 2024 膵島内環境における細胞代謝変化と自己免疫性糖尿病進展の関連性の検討
  • 2015 - 2016 Investigation for development of new strategy for type 1 diabetes targeting pioneer transcriptional factor IRF4/8
  • 2012 - 2015 Development of effector cell-targeted treatment for the inhibition of type 1 diabetes
  • 2011 - 2012 Development of new therapy for type 1 diabetes targeting for IRF-4 (interferon regulatory factor-4)
Papers (53)：
  • Tetsuro Niri, Shin-Ichi Inoue, Satoru Akazawa, Shinpei Nishikido, Masaki Miwa, Masakazu Kobayashi, Katsuyuki Yui, Minoru Okita, Atsushi Kawakami, Norio Abiru. Essential role of interferon-regulatory factor 4 in regulating diabetogenic CD4+ T and innate immune cells in autoimmune diabetes in NOD mice. Clinical and experimental immunology. 2024
  • Keiichiro Mine, Seiho Nagafuchi, Satoru Akazawa, Norio Abiru, Hitoe Mori, Hironori Kurisaki, Kazuya Shimoda, Yasunobu Yoshikai, Hirokazu Takahashi, Keizo Anzai. TYK2 signaling promotes the development of autoreactive CD8+ cytotoxic T lymphocytes and type 1 diabetes. Nature communications. 2024. 15. 1. 1337-1337
  • 錦戸 慎平, 赤澤 諭, 三輪 昌輝, 二里 哲朗, 阿比留 教生. 自己免疫性糖尿病における5-Aminolevulinic acidの有効性の検討. 日本先進糖尿病治療研究会雑誌. 2023. 17. 3. 149-149
  • Kantoku Nagakawa, Akihiko Soyama, Takanobu Hara, Hajime Matsushima, Hajime Imamura, Takayuki Tanaka, Michi Morita, Sakaya Kuba, Tomohiko Adachi, Masaaki Hidaka, et al. Living donor liver transplantation for a patient with acute liver failure following thyroid storm: a case report. Surgical case reports. 2023. 9. 1. 208-208
  • 錦戸 慎平, 赤澤 諭, 二里 哲朗, 三輪 昌輝, 阿比留 教生. 抗原特異的CD8+T細胞のIRF4ハプロ不全は膵島炎から糖尿病自然発症への進展を完全に抑制する. 日本先進糖尿病治療研究会雑誌. 2023. 17. 2. 108-108
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MISC (91)：
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Lectures and oral presentations  (10)：
  • The rule of interferons in the pathogenesis of autoimmune diabetes
    (The 58th Annual congress for Progress of Diabetology in Japan 2024)
  • Innate Immunity in type 1 diabetes - Interferons and Autoimmunity for Islets -
    (65th Annual congress of Japan Diabetes Society 2022)
  • STING deficiency promotes the development of autoimmune diabetes in NOD mice.
    (The 16th International Congress of Immunology of Diabetes Society 2018)
  • Anti-inflammatory effects of interferons inhibit progression of diabetes in NOD mice
    (ThymOz international conference 2018 2018)
  • The effect of STING deficiency on development of autoimmune diabetes in NOD mice
    (The 46th Annual Scientific Meeting of The Australian Society for Immunology 2017)
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Education (2)：
  • 2009 - The Nagasaki University Graduate School of Biomedical Sciences
  • 1999 - 2005 Shimane Medical University
Professional career (1)：
  • Ph.D. (Nagasaki University)
Work history (3)：
  • 2022/01 - 現在 Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University Department of Endocrinology and Metabolism, Unit of Translational Medicine
  • 2019/04 - 現在 Atomic Bomb Disease Institute, Nagasaki University Department of Global Health, Medicine and Welfare Assistant professor
  • 2016/04 - 2019/03 St. Vincent's Institute of medical Research Islet Biology Laboratory, The Immunology and Diabetes Unit Post-doctoral fellow
Awards (3)：
  • 2017/04 - Juvenile Diabetes Research Foundation (JDRF) Post-doctoral fellowship Defining a new role for granzyme A in maintaining immune tolerance.
  • 2016/04 - The Manpei Suzuki Diabetes Foundation Post-doctoral fellowship New approaches to inducing tolerance in autoantigen specific memory T cells
  • 2013/02 - The Japan Society of Experimental Diabetes and Obesity Young Investigator Award
Association Membership(s) (5)：
The Japan Endocrine Society ,  The Japan Society for Clinical Immunology ,  Japan Diabetes Society ,  The Japanese Society of Internal Medicine ,  Immunology of Diabetes Society
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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