Iwasaki Takashi

イワサキタカシ | Iwasaki Takashi

Affiliation and department：
Job title： Associate professor

Research field (1)： Bioorganic chemistry

Research keywords (7)： Genome editing , Protein engineering , Cell-penetrating peptide , 細胞内輸送 , Drug delivery , Mammalian cell , Plant cell

Research theme for competitive and other funds (12)：

2024 - 2027 イヌ膀胱腫瘍に対する光増感剤修飾抗HER2ナノボディを用いた光線力学療法の開発
2024 - 2027 Development of rapid crop breeding system "Protein-driven breeding"
2021 - 2025 Development of precise genome editing technology without genetic transformation or tissue culture in conifer species.
2020 - 2023 ヒスチジン立体配置に基づいた細胞膜透過性タンパク質ファミリーの探索と機能解析
2017 - 2020 Analysis for cell-penetrating mechanism of histidine-rich peptide/proteins

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Papers (36)：

Toshikuni Awazu, Kanato Sakamoto, Yuka Minagi, Masumi Ohnishi, Tomohiro Bito, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano. The small GTPase RAB-18 is involved in regulating development/diapause by recruiting the intestinal cholesterol transporter NCR-1 onto the apical side in Caenorhabditis elegans. Biochemical and Biophysical Research Communications. 2024. 734. 150609-150609
Soei Watari, Hiroshi Inaba, Qianru H Lv, Muneyoshi Ichikawa, Takashi Iwasaki, Bingxun Wang, Hisashi Tadakuma, Akira Kakugo, Kazunori Matsuura. Optical Control of Microtubule Accumulation and Dispersion by Tau-Derived Peptide-Fused Photo-Responsive Protein. 2024
Masahiro Ono, Kenjiro Matsushita, Sho Maega, Naoto Asano, Yohei Matsunaga, Tomohiro Bito, Takashi Iwasaki, Tsuyoshi Kawano. The G protein-coupled receptor neuropeptide receptor-15 modulates larval development via the transforming growth factor-β DAF-7 protein in Caenorhabditis elegans. Biochemical and Biophysical Research Communications. 2023. 660. 28-34
Kentarou Sakamoto, Kohsuke Uchiyama, Takashi Iwasaki, Hiroshi Inaba, Kazunori Matsuura. An artificial viral capsid decorated with a DNA aptamer internalizing into lymphoma cells. Journal of Materials Chemistry B. 2023
Risako Une, Natsumi Kageyama, Masahiro Ono, Yohei Matsunaga, Takashi Iwasaki, Tsuyoshi Kawano. The FMRFamide-like peptide FLP-1 modulates larval development by regulating the production and secretion of the insulin-like peptide DAF-28 in Caenorhabditis elegans. Bioscience, Biotechnology, and Biochemistry. 2022. in press

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MISC (60)：

田中淑乃, 七里吉彦, 大村昂誠, 遠藤圭太, 河野強, 岩崎崇. Non-transgenic plant genome editing methods using cell-penetrating peptides. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
岩崎崇. 新規細胞膜透過ペプチドを利用したエクソソームノックダウン法の開発. 医科学応用研究財団研究報告(CD-ROM). 2022. 39
末岐優里菜, 稲葉央, 岩崎崇, KABIR Arif Md. Rashedul, 角五彰, 佐田和己, 松浦和則. Stabilization of microtubules by encapsulation of tetrameric fluorescent proteins using Tau-derived peptides. 日本化学会春季年会講演予稿集(Web). 2021. 101st
岩崎崇, 岩崎崇, 金山葉瑠, 下田麻由, 河野強, 河野強. Pathogenic mechanism of Histidine-rich protein 2 produced by Plasmodium falciparum. 日本農芸化学会大会講演要旨集(Web). 2021. 2021
皆木友花, 粟津利邦, 松浦雅実, 松永洋平, 岩崎崇, 岩崎崇, 河野強, 河野強. Molecular mechanism of Rab-18, a small G-protein, in C. elegans larval development. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th

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Patents (6)：

植物細胞に遺伝子を導入するための複合体
タンパク質を内包した人工微小管
細胞膜透過ペプチドを利用した遺伝子組換えに頼らない植物ゲノム編集技術
新規細胞膜透過ペプチド
抗微生物ペプチドを固定化した素材

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Books (3)：

新しい細胞ペプチド『ポリヒスチジン』の発見と応用研究
情報技術協会 2017
抗菌ペプチドの機能解明と技術利用
CMC出版 2017
最新昆虫病理学
講談社 2014

Lectures and oral presentations (5)：

細胞膜透過ペプチド:ポリヒスチジンを利用した医療・農業応用研究
(日本ビタミン学会第1回次世代シンポジウム 2023)
Discovery and applied studies of polyhistidine peptides
(第59回ペプチド討論会 2022)
Development of Cell-Penetrating Peptides as Molecular Delivery Carriers for Human Health and Plant Breeding
(AFELiSA 2018 2018)
細胞膜透過ペプチド:ポリヒスチジンを利用した動物・植物細胞に対する分子輸送
(日本農薬学会第43回大会 2018)
細胞膜透過ペプチド『ポリヒスチジン』の発見と動物・植物細胞に対する応用研究
(日本農芸化学会中四国支部第26回若手研究者シンポジウム 2017)

Education (2)：

2005 - 2009 University of Tsukuba
2001 - 2005 Hiroshima University Faculty of Science Department of Biological Science

Work history (4)：

2016/10 - 現在 Tottori University Faculty of Agriculture
2010/04 - 2016/09 Tottori University Faculty of Agriculture
2009/04 - 2010/03 日本学術振興会特別研究員PD
2007/04 - 2009/03 日本学術振興会特別研究員DC1

Awards (11)：

2024/01 - 鳥取大学学長表彰
2023/03 - 2022 B.B.B. paper award In vitro transcytosis of Helicobacter pylori histidine-rich protein through gastric epithelial-like cells and the blood-brain barrier
2022/07 - Japanese Peptide Society Japanese Peptide Society Award for Young Investigator
2022/03 - 2021 B.B.B. paper award Direct protein delivery into intact plant cells using polyhistidine peptides
2014/09 - 日本農芸化学会中四国支部奨励賞

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Association Membership(s) (4)：

JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , Japanese Society for Plant Biotechnology , The Japanese Peptide Society , JAPAN SOCIETY FOR BIOSCIENCE

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