J-GLOBAL ID:201901011820277110   Update date: Jul. 12, 2022

Deguchi Tatsuya

デグチ タツヤ | Deguchi Tatsuya
Affiliation and department:
Research field  (1): Tumor biology
Research keywords  (5): Immunotherapy ,  Veterinary Medicine ,  Mitochondria ,  Cancer stem-like cells ,  Radiation Oncology
Research theme for competitive and other funds  (3):
  • 2020 - 2022 イヌ腫瘍に対するミトコンドリア代謝阻害薬の放射線増感効果に関する臨床研究
  • 2019 - 2021 イヌ腫瘍の免疫抑制機構阻害剤の放射線増感効果における臨床研究
  • 2016 - 2017 犬の鼻腔腫瘍に対するテーラーメイド放射線治療に向けた癌幹細胞の性質の同定
Papers (16):
  • Naoya Maekawa, Satoru Konnai, Yumie Asano, Yamato Sajiki, Tatsuya Deguchi, Tomohiro Okagawa, Kei Watari, Hiroto Takeuchi, Satoshi Takagi, Kenji Hosoya, et al. Exploration of serum biomarkers in dogs with malignant melanoma receiving anti-PD-L1 therapy and potential of COX-2 inhibition for combination therapy. Scientific reports. 2022. 12. 1. 9265-9265
  • Koangyong Sung, Kenji Hosoya, Yusuke Murase, Tatsuya Deguchi, Sangho Kim, Takafumi Sunaga, Masahiro Okumura. Visualizing the cancer stem-like properties of canine tumour cells with low proteasome activity. Veterinary and comparative oncology. 2021
  • Tatsuya Deguchi, Kenji Hosoya, Shango Kim, Yusuke Murase, Kumiko Yamamoto, Tomoki Bo, Hironobu Yasui, Osamu Inanami, Mahiro Okumura. Metformin preferentially enhances the radio-sensitivity of cancer stem-like cells with highly mitochondrial respiration ability in HMPOS. Molecular therapy oncolytics. 2021. 22. 143-151
  • 大脇 稜, 出口 辰弥, 今内 覚, 前川 直也, 細谷 謙次, 金 尚昊, 須永 隆文, 奥村 正裕. イヌ腫瘍細胞株におけるProgrammed cell death-ligand 1の発現機序の解析. 日本獣医学会学術集会講演要旨集. 2021. 164回. [HSO-19]
  • Sangho Kim, Kenji Hosoya, Natsuki Fukayama, Tatsuya Deguchi, Masahiro Okumura. Safety and efficacy of a nonmyeloablative pretransplant conditioning regimen using total lymphoid irradiation with volumetric modulated arc therapy in healthy dogs: A pilot study. Veterinary medicine and science. 2021. 7. 4. 1120-1130
MISC (25):
Lectures and oral presentations  (16):
  • 強度変調回転照射法を用いて定位放射線治療を実施した犬の鼻腔腫瘍41例
    (令和3年度日本小動物獣医学会 北海道地区学会 2021)
  • 神経膠腫の脊髄への滴下転移に対して全脊髄照射を実施した犬の1例
    (第21回日本獣医がん学会 2019)
  • イヌ骨肉腫細胞株由来Cancer stem-like cellsのミトコンドリアの放射線反応性の解析
    (第72回日本酸化ストレス学会 学術集会 2019)
  • メトホルミンのイヌ骨肉腫細胞株由来のCancer stem-like cellsにおける放射線増感効果の解析
    (第21回癌治療増感研究シンポジウム 2019)
  • Metformin radio-sensitizes cancer stem-like cells but not no-stem cells in canine osteosarcoma cell line by AMPK/mTOR-independent mechanism.
    (2018 Veterinary Cancer Society (VCS) Annual Conference 2018)
Education (2):
  • 2015 - 2019 Hokkaido University Laboratory of Veterinary Surgery
  • 2007 - 2013 Azabu University Veterinary Medicine
Professional career (1):
  • Doctor of veterinary medicine (Hokkaido University)
Work history (2):
  • 2022/04 - 現在 Rakuno Gakuen University School of Veterinary Medicine
  • 2019/04 - 2022/03 Hokkaido University Veterinary Teaching Hospital, Graduate School of Veterinary Medicine Specially Appointed Assistant Professor
Awards (2):
  • 2021/10 - 日本小動物獣医学会(北海道) 北海道地区学会長賞 強度変調回転照射法を用いて定位放射線治療を実施した犬の鼻腔腫瘍 41 例
  • 2015/12 - Japanese Society of Veterinary Anesthesia and Surgery Outstanding performance award
Association Membership(s) (3):
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