Rchr
J-GLOBAL ID：201901011831408232   Update date: Jul. 21, 2024

Ohashi Rie

オオハシ リエ | Ohashi Rie
Affiliation and department：
University of Toyama

About University of Toyama


Research field  (2)： Neuroscience - general ,  Cell biology
Research keywords  (8)： 長期記憶 ,  記憶 ,  神経細胞 ,  RNA顆粒 ,  RNA結合タンパク質 ,  樹状突起 ,  局所的翻訳 ,  mRNA輸送
Research theme for competitive and other funds  (6)：
  • 2023 - 2026 長期記憶形成における神経樹状突起内局所翻訳の制御機構
  • 2020 - 2023 樹状突起における局所翻訳が高次脳機能に果たす役割の解明
  • 2021 - 2023 mRNA輸送及び局所翻訳による長期記憶形成メカニズムの解明
  • 2019 - 2022 長期記憶形成時の脳内における局所翻訳の可視化とその制御
  • 2021 - mRNA輸送及び局所翻訳による長期記憶形成メカニズムの解明
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Papers (5)：
  • Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2024. 12
  • Tomoyo Horio, Yui Ishikura, Rie Ohashi, Nobuyuki Shiina. Regulation of RNG105/caprin1 dynamics by pathogenic cytoplasmic FUS and TDP-43 in neuronal RNA granules modulates synaptic loss. Heliyon. 2023. 9. 6. e17065
  • Rie Ohashi, Nobuyuki Shiina. Cataloguing and Selection of mRNAs Localized to Dendrites in Neurons and Regulated by RNA-Binding Proteins in RNA Granules. Biomolecules. 2020. 10. 2. 167
  • Kei Nakayama, Rie Ohashi, Yo Shinoda, Maya Yamazaki, Manabu Abe, Akihiro Fujikawa, Shuji Shigenobu, Akira Futatsugi, Masaharu Noda, Katsuhiko Mikoshiba, et al. RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation. eLife. 2017. 6. e29677
  • Rie Ohashi, Keizo Takao, Tsuyoshi Miyakawa, Nobuyuki Shiina. Comprehensive behavioral analysis of RNG105 (Caprin1) heterozygous mice: Reduced social interaction and attenuated response to novelty. Scientific reports. 2016. 6. 20775
MISC (2)：
  • 大橋りえ, 椎名伸之. 神経RNA顆粒が制御する局所翻訳と長期記憶形成. 生化学. 2022. 94. 4. 529-536
  • 椎名伸之, 中山啓, 大橋りえ. 長期記憶に不可欠な分子RNG105 - ニューロンでのタンパク質合成と長期記憶形成をつなぐ仕組み. academist Journal. 2017
Lectures and oral presentations  (13)：
  • Arf GEF mRNAの神経樹状突起局在制御がスパイン形成・成熟に与える影響
    (第46回日本分子生物学会年会 2023)
  • Arf GEF, GAPファミリーmRNAの神経樹状突起局在制御がシナプス形成に与える影響
    (第45回日本分子生物学会年会 2022)
  • RNA granule protein RNG105 (caprin1) regulates dendritic mRNA localization and contributes to synaptic potentiation
    (第42回日本分子生物学会年会 2019)
  • Dendritic localization of mRNAs for Arf GEFs and GAPs that are involved in spine formation/maturation and AMPAR surface expression in dendrites
    (日本神経科学会 Neuro2019 2019)
  • Dendritic localization of mRNAs for Arf GEFs and GAPs involved in spine formation in dendrites
    (第41回日本分子生物学会年会 2018)
ｍore...
Education (2)：
  • 2014 - 2019 The Graduate University for Advanced Studies School of Life Science Department of Basic Biology
  • 2010 - 2014 Tokyo University of Science Faculty of Science and Technology Applied Biological Science
Professional career (1)：
  • 博士(理学) (総合研究大学院大学)
Work history (6)：
  • 2021/01 - 現在 富山大学 協力研究員
  • 2021/01 - 2024/06 SOKENDAI Assistant Professor
  • 2021/01 - 2024/06 National Institutes of Natural Sciences National Institute for Basic Biology Assistant Professor
  • 2021/01 - 2024/06 National Institutes of Natural Sciences Exploratory Research Center on Life and Living Systems Assistant Professor
  • 2019/04 - 2020/12 日本学術振興会特別研究員 PD (富山大学)
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Awards (1)：
  • 2019/03 - 総合研究大学院大学 生命科学研究科長賞
Association Membership(s) (3)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPAN NEUROSCIENCE SOCIETY ,  Society for Neuroscience
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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