Rchr
J-GLOBAL ID：201901012145277381
Update date: Jul. 11, 2024
Sugiura Daisuke
スギウラ ダイスケ | Sugiura Daisuke
Affiliation and department：
Research field (1)：
Immunology
Research keywords (3)：
免疫補助受容体
, T細胞
, 免疫学
Research theme for competitive and other funds (2)：
- 2021 - 2024 シスPD-L1/CD80結合が自己免疫応答に与える影響の解明
- 2006 - 2008 MUC1 DNAワクチンによる大腸癌の治療・転移の抑制
Papers (22)：
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Retno Murwanti, Kaori Denda-Nagai, Daisuke Sugiura, Kaoru Mogushi, Sandra J. Gendler, Tatsuro Irimura. Prevention of Inflammation-Driven Colon Carcinogenesis in Human MUC1 Transgenic Mice by Vaccination with MUC1 DNA and Dendritic Cells. Cancers. 2023
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Takumi Maruhashi, Daisuke Sugiura, Il-mi Okazaki, Kenji Shimizu, Takeo K. Maeda, Jun Ikubo, Harunori Yoshikawa, Katsumi Maenaka, Naozumi Ishimaru, Hidetaka Kosako, et al. Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity. Immunity. 2022
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Daisuke Sugiura, Il-Mi Okazaki, Takeo K Maeda, Takumi Maruhashi, Kenji Shimizu, Rieko Arakaki, Tatsuya Takemoto, Naozumi Ishimaru, Taku Okazaki. PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity. Nature immunology. 2022. 23. 3. 399-410
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Daisuke Sugiura, Kenji Shimizu, Takumi Maruhashi, Il-Mi Okazaki, Taku Okazaki. T cell-intrinsic and -extrinsic regulation of PD-1 function. International immunology. 2021. 33. 12. 693-698
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Kenji Shimizu, Daisuke Sugiura, Il-Mi Okazaki, Takumi Maruhashi, Tatsuya Takemoto, Taku Okazaki. PD-1 preferentially inhibits the activation of low-affinity T cells. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 35
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MISC (7)：
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杉浦大祐, 岡崎 拓. PD-1の機能制限解除による自己免疫疾患の治療. 実験医学. 2022. 40. 13. 2172-2175
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杉浦 大祐, 岡崎 拓. 至適なT細胞応答のためのPD-1機能制限機構. 臨床免疫・アレルギー科. 2020. 73. 3. 348-354
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杉浦大祐, 岡崎拓. 抑制性免疫補助受容体PD-1が有益な免疫応答を抑制しないメカニズム. 感染・炎症・免疫. 2020. 50. 1. 56-57
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T. Kajihara, D. Sugiura, T. Maruhashi, I. -M Okazaki, T. Okazaki. Inhibition of T cell activation by human LAG-3. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 710-710
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T. Maruhashi, I. -M Okazaki, D. Sugiura, T. Okazaki. Context-dependent inhibition of antigen-specific T cell activation by LAG-3. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 710-710
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Education (2)：
- - 2009 The University of Tokyo Graduate School of Pharmaceutical Sciences
- - 2004 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1)：
Work history (6)：
Awards (2)：
- 2019 - 日本免疫学会研究奨励賞
- 2019 - 徳島大学若手研究者学長表彰
Association Membership(s) (1)：
THE JAPANESE SOCIETY FOR IMMUNOLOGY
