Rchr
J-GLOBAL ID：201901012847446840   Update date: May. 30, 2024

Hirota Toru

Hirota Toru
Affiliation and department：
Japanese Foundation for Cancer Research

About Japanese Foundation for Cancer Research


Homepage URL  (1)： https://www.jfcr.or.jp/tci/exppathol/
Research field  (2)： Genetics ,  Tumor biology
Research theme for competitive and other funds  (26)：
  • 2022 - 2027 Plastic regulation of chromosome dynamics in cancer
  • 2022 - 2026 RNAと染色体骨格タンパク質群による液-液相分離現象が促すM期染色体制御
  • 2022 - 2026 Pathological relevance of chromosomal instaiblity in cancers
  • 2019 - 2023 Analysis of a novel regulatory system of mitosis through nucleolar dynamics
  • 2018 - 2022 Regulation of the Chromosomal Passenger Complex identifies pathology of chromosomal instability in cancers
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Papers (84)：
  • Kosuke Sako, Ayako Furukawa, Ryu-Suke Nozawa, Jun-Ichi Kurita, Yoshifumi Nishimura, Toru Hirota. Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres. The Journal of cell biology. 2024. 223. 9
  • Masatoshi Hara, Mariko Ariyoshi, Tomoki Sano, Ryu-Suke Nozawa, Soya Shinkai, Shuichi Onami, Isabelle Jansen, Toru Hirota, Tatsuo Fukagawa. Centromere/kinetochore is assembled through CENP-C oligomerization. Molecular Cell. 2023. 83. 13. 2188-2205.e13
  • Norihisa Shindo, Kazuki Kumada, Kenji Iemura, Jun Yasuda, Haruna Fujimori, Mai Mochizuki, Keiichi Tamai, Kozo Tanaka, Toru Hirota. Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1. Cell reports. 2022. 41. 9. 111723-111723
  • Tetsuya Negoto, Minji Jo, Izuma Nakayama, Motohiro Morioka, Kengo Takeuchi, Hiroshi Kawachi, Toru Hirota. Profiling chromosomal-level variations in gastric malignancies. Cancer science. 2022. 113. 11. 3864-3876
  • Kenichi Miyata, Yoshinori Imai, Satoshi Hori, Mika Nishio, Tze Mun Loo, Ryo Okada, Liying Yang, Tomoyoshi Nakadai, Reo Maruyama, Risa Fujii, et al. Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 35
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MISC (179)：
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Patents (2)：
Professional career (1)：
  • 医学博士 (新潟大学)
Work history (4)：
  • 2005/10 - 現在 Japanese Foundation for Cancer Research
  • 2004/04 - 2005/09 JSPS Postdoctral Fellowship for Research Abroad.
  • 2001/04 - 2004/03 JSPS Research Fellow (PD)
  • 1996/04 - 2000/09 Niigata University Graduate School of Medical Science
Awards (2)：
  • 2006/10 - Japanese Cancer Association The Young Investigator Awards
  • 2006/08 - Niigata University Yujinkinen Gakujutsu Shorei Prize
Association Membership(s) (2)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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